p21(WAF1/CIP1) expression in non-melanoma skin tumors

Journal of Cutaneous Pathology

Volumn 24, Issue 4, 1997, Pages 223-227

  Ahmed, Nazim U ^a   Ueda, Masato ^a   Ichihashi, Masamitsu ^a  

^a KOBE UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P21; ANTIBODY; CDKN1A PROTEIN, HUMAN; COLORING AGENT; CYCLIN DEPENDENT KINASE INHIBITOR 1A; CYCLINE; ENZYME INHIBITOR; PROTEIN P53;

ACTINIC KERATOSIS; ARTICLE; BASAL CELL CARCINOMA; BOWEN DISEASE; CELL CYCLE; CELL PROLIFERATION; CELLULAR DISTRIBUTION; EPIDERMIS; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; KERATINOCYTE; KERATOACANTHOMA; PROTEIN EXPRESSION; SEBACEOUS GLAND; SEBORRHEIC KERATOSIS; SKIN TUMOR; SQUAMOUS CELL CARCINOMA; TUMOR GROWTH; BIOSYNTHESIS; CHEMISTRY; IMMUNOLOGY; KERATOSIS; MELANOMA; METABOLISM; PATHOLOGY; PRECANCER; SKIN;

ANTIBODIES; COLORING AGENTS; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLINS; ENZYME INHIBITORS; HUMANS; KERATOSIS; KERATOSIS, SEBORRHEIC; MELANOMA; PRECANCEROUS CONDITIONS; SKIN; SKIN NEOPLASMS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0030612154     PISSN: 03036987     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0560.1997.tb01585.x     Document Type: Article

References (19)

1. Xiong Y, Hannon GJ, Zhang H, Casso D, Kobayashi R, Beach D. p21 is a universal inhibitor of cyclin kinases. Nature 1993: 366: 701.
2. Harper JW, Adami GR, Wei N, Keyomarsi K, Elledge SJ. The p21-cdk-interacting protein cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell 1993: 70: 805.
3. Waga S, Hannon GJ, Beach D, Stillman B. The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA. Nature 1994: 369: 574.
4. El-Deiry WS, Harper JW, O'Connor PM, et al. WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis. Cancer Res 1994: 54: 1169.
5. Zhang W, Grasso L, McClain CD, et al. p53-independent induction of WAF1/CIP1 in human leukemia cells is correlated with growth arrest accompanying monocyte/macrophage differentiation. Cancer Res 1995: 55: 668.
6. Eastham JA, Hall SJ, Sehgal I, et al. In vivo gene therapy with p53 or p21 adenovirus for prostate cancer. Cancer Res 1995: 55: 5151.
7. Shiohara M, El-Deiry WS, Wada M, et al. Absence of WAF1 mutations in a variety of human malignancies. Blood 1994: 84: 3781.
8. Steinman RA, Hoffman B, Iro A, Guillouf C., Liebermann DA, El-Houseini ME. Induction of p21 (WAF-1/CIP1) during differentiation. Oncogene 1994: 9: 3389.
9. Weinberg WC, Azzoli CG, Chapman K, Levine AJ, Yuspa SH. p53-mediated transcriptional activity increases in differentiating epidermal keratinocytes in association with decreased p53 protein. Oncogene 1995: 10: 2271.
10. Missero C., Calautti E, Eckner R, et al. Involvement of the cell-cycle inhibitor Cip1/WAF1 and the E1A-associated p300 protein in terminal differentiation. Proc Natl Acad Sci USA 1995: 92: 5451.
11. Ziegler A, Jonason AS, Leffell DJ, et al. Sunburn and p53 in the onset of skin cancer. Nature 1994: 372: 773.
12. Bito T, Ueda M, Ahmed NU, Nagano T, Ichihashi M. Cyclin D and retinoblastoma gene product expression in actinic keratosis and cutaneous squamous cell carcinoma in relation to p53 expression. J Cutan Pathol 1995: 22: 427.
13. WAF1/CIP1 expression in normal and neoplastic tissues, Cancer Res 1995: 55: 2910.
14. WAF1/CIP1 in human brain tumors. Oncogene 1995: 11: 2021.
15. WAF1/CIP1 heterogeneous and unrelated to proliferation index in human ovarian carcinoma. Int J Cancer 1995: 63: 611.
16. Finlay CA, Hinds PW, Tan T, Eliyahu D, Oren M, Levine AJ. Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life. Mol Cell Biol 1988: 8: 531.
17. WAF1/CIP1 in psoriasis and after the application of irritants and tape stripping. J Invest Dermatol 1995: 105: 274.
18. Lever WF, Schaumburg-Lever G. Histopathology of the skin. 7th edn. Philadelphia: JB Lippincott, 1990: 632.
19. DiGiuseppe JA, Redson MS, Yeo CY, Kern SE, Hruban RH. p53-independent expression of the cyclin-dependent kinase inhibitor p21 in pancreatic carcinoma. Am J Pathol 1995: 147: 884.