Inthrathecal IgA synthesis in X-linked cerebral adrenoleukodystrophy

Journal of Child Neurology

Volumn 12, Issue 5, 1997, Pages 314-320

  Korenke, G Christoph ^a   Reiber, Hansotto ^a   Hunneman, Donald H ^a   Hanefeld, Folker ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; BETA INTERFERON; GADOLINIUM; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; LACTIC ACID; PROTEIN; STEROID; TRIOLEIN; VERY LONG CHAIN FATTY ACID;

ADOLESCENT; ADRENOLEUKODYSTROPHY; ADULT; ARTICLE; BLOOD CEREBROSPINAL FLUID BARRIER; CEREBROSPINAL FLUID; CEREBROSPINAL FLUID ANALYSIS; CHILD; CLINICAL ARTICLE; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; IMMUNOGLOBULIN PRODUCTION; ISOELECTRIC FOCUSING; LUMBAR PUNCTURE; NEPHELOMETRY; NEUROPSYCHOLOGICAL TEST; NUCLEAR MAGNETIC RESONANCE IMAGING; PHENOTYPE; PRIORITY JOURNAL; X CHROMOSOME LINKED DISORDER; BIOSYNTHESIS; CLASSIFICATION; CROSS-SECTIONAL STUDY; DISCRIMINANT ANALYSIS; DISEASE COURSE; GENETIC LINKAGE; IMMUNOLOGY; LONGITUDINAL STUDY; MALE; MIDDLE AGED; PRESCHOOL CHILD; X CHROMOSOME;

ADOLESCENT; ADRENOLEUKODYSTROPHY; ADULT; CHILD; CHILD, PRESCHOOL; CROSS-SECTIONAL STUDIES; DISCRIMINANT ANALYSIS; DISEASE PROGRESSION; HUMANS; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; LINKAGE (GENETICS); LONGITUDINAL STUDIES; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; PHENOTYPE; X CHROMOSOME;

EID: 0030612059     PISSN: 08830738     EISSN: None     Source Type: Journal    
DOI: 10.1177/088307389701200505     Document Type: Article

References (23)

1. Moser HW, Moser AB, Smith KD, et al: Adrenoleukodystrophy: Phenotypic variability and implications for therapy. J Inherited Metab Dis 1992;15:645-666.
2. Aubourg P, Adamsbaum C, Lavallard-Rousseau MC, et al: A two-year trial of oleic and erucic acids ("Lorenzo's oil") as treatment for adrenomyeloneuropathy. N Engl J Med 1993;329:745-752.
3. Fuchs S, Sarde CO, Wedemann H, et al: Missense mutations are frequent in the gene for X-chromosomal adrenoleukodystrophy (ALD). Hum Mol Genet 1994;3:1903-1905.
4. Braun A, Ambach H, Kammerer S, et al: Mutations in the gene for X-linked adrenoleukodystrophy in patients with different clinical phenotypes. Am J Hum Genet 1995;56:854-861.
5. Ligtenberg MJ, Kemp S, Sarde CO, et al: Spectrum of mutations in the gene encoding the adrenoleukodystrophy protein. Am J Hum Genet 1995;56:44-50.
6. Watkins PA, Gould SJ, Smith MA, et al: Altered expression of ALDP in X-linked adrenoleukodystrophy. Am J Hum. Genet 1995; 57:292-301.
7. Krasemann E, Meier V, Korenke GC, et al: Identification of mutations in the ALD-gene of 20 families with adrenoleukodystrophy/adrenomyeloneuropathy. Hum Genet 1996;97:194-197.
8. Schaumburg HH, Powers JM, Raine CS, et al: Adrenoleukodystrophy. A clinical and pathological study of 17 cases. Arch Neurol 1975;32:577-591.
9. Bernheimer H, Budka H, Muller P: Brain tissue immunoglobulins in adrenoleukodystrophy: A comparison with multiple sclerosis and systemic lupus erythematosus. Acta Neuropathol (Berl) 1983; 59:95-102.
10. Griffin DE, Moser HW, Mendoza Q, et al: Identification of the inflammatory cells in the central nervous system of patients with adrenoleukodystrophy. Ann Neurol 1985;18:660-664.
11. Phillips JP, Lockman LA, Shapiro EG, et al: CSF findings in adrenoleukodystrophy: Correlation between measures of cytokines, IgG production, and disease severity. Pediatr Neurol 1994;10:289-294.
12. Reiber H: Flow rate of cerebrospinal fluid CSF: A concept common to normal blood-CSF barrier function and to dysfunction in neurological diseases. J Neurol Sci 1994;22:189-203.
13. Reiber H: External quality assessment in clinical neurochemistry: Survey of analysis for cerebrospinal fluid (CSF) proteins based on CSF/serum quotients. Clin Chem 1995;41:256-263.
14. Reiber H: Die diagnostische Bedeutung neuroimmunologischer Reaktionsmuster im Liquor cerebrospinalis. Lab Med 1995;19: 444-462.
15. Tumani H, Nölker G, Reiber H: Relevance of cerebrospinal fluid variables for early diagnosis of neuroborreliosis. Neurology 1995; 45:1663-1670.
16. Anderson M, Alvarez-Cermeno J, Bernadi G, et al: Cerebrospinal fluid in the diagnosis of multiple sclerosis: A consensus report. J Neurol Neurosurg Psychiatry 1994;57:897-902.
17. Hunneman DH, Hanefeld F: Diagnose von peroxisomalen Erkrankungen - Erfahrungen mit einer empfindlichen massenfragmentographischen Bestimmung der sehr langkettigen Fettsäuren und der Phytansäure im Plasma. Monatsschr Kinderheilkd 1988;136:529.
18. Korenke G-C, Hunneman DH, Kohler J, et al: Glyceroltrioleate/glyceroltrierucate therapy in 16 patients with X-chromosomal adrenoleukodystrophy/adrenomyeloneuropathy: Effect on clinical, biochemical and neurophysiological parameters. Eur J Pediatr 1995;154:64-70.
19. Loes DJ, Hite S, Moser H, et al: Adrenoleukodystrophy: A scoring method for brain MR observations. AJNR Am J Neuroradiol 1994;15:1761-1766.
20. Reiber H, Lange P: Quantification of virus-specific antibodies in cerebrospinal fluid and serum: Sensitive and specific detection of antibody synthesis in brain. Clin Chem 1991;37:1153-1160.
21. Powers JM, Liu Y, Moser AB, Moser HW: The inflammatory myelinopathy of adreno-leukodystrophy: Cells, effector molecules, and pathogenetic implications. J Neuropathol Exp Neurol 1992;51:630-643.
22. Felgenhauer K, Reiber H: The diagnostic significance of antibody specificity indices in multiple sclerosis and herpes virus induced diseases of the nervous system. Clin Investig 1992;70:28-37.
23. Graef IT, Henze T, Reiber H: Polyspezifische Immunreaktion im ZNS bei Autoimmunerkrankungen mit ZNS-Beteiligung. Z Artzl Fortbild (Jena) 1994;88:587-591.