Novel 99mTc aminobisthiolato/monothiolato '3 + 1' mixed ligand complexes: Structure-activity relationships and preliminary in vivo validation as brain blood flow imaging agents

Journal of Medicinal Chemistry

Volumn 40, Issue 16, 1997, Pages 2539-2546

  Pirmettis, Ioannis C ^a   Papadopoulos, Minas S ^a   Chiotellis, Efstratios ^a  

^a INSTITUTE OF NANOSCIENCE AND NANOTECHNOLOGY   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOHEPTONIC ACID; HEXAMETHYLPROPYLENE AMINE OXIME TECHNETIUM TC 99M; LIGAND; OXIME; RADIOPHARMACEUTICAL AGENT; SUGAR ACID; TECHNETIUM COMPLEX; TECHNETIUM TC 99M GLUCEPTATE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BINDING AFFINITY; BRAIN BLOOD FLOW; BRAIN CORTEX; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMAGE ANALYSIS; LIGAND BINDING; LIPOPHILICITY; NONHUMAN; RAT; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; STRUCTURE ACTIVITY RELATION; ANIMAL; BRAIN; BRAIN CIRCULATION; CHEMICAL STRUCTURE; MOLECULAR WEIGHT; MOUSE; PH; SCINTISCANNING; SYNTHESIS; VASCULARIZATION; X RAY CRYSTALLOGRAPHY;

ANIMALS; BRAIN; CEREBROVASCULAR CIRCULATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CRYSTALLOGRAPHY, X-RAY; HYDROGEN-ION CONCENTRATION; LIGANDS; MICE; MODELS, MOLECULAR; MOLECULAR WEIGHT; ORGANOTECHNETIUM COMPOUNDS; OXIMES; RADIOPHARMACEUTICALS; RATS; STRUCTURE-ACTIVITY RELATIONSHIP; SUGAR ACIDS; TECHNETIUM TC 99M EXAMETAZIME; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON;

EID: 0030611266     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm960273y     Document Type: Article

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