Hyperplastic lesions of the larynx. Experience of the Barcelona Group

Acta Oto-Laryngologica, Supplement

Volumn , Issue 527, 1997, Pages 43-46

  Cardesa, Antonio ^a   Nadal, Alfons ^b   Jares, Pedro ^a   Mallofré, Carme ^a   Fernández, Pedro L ^a   Campo, Elías ^a   Traserra, José ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

^b Hospital Casa de Maternitat   (Spain)

Author keywords

cyclin D1; cytokeratins; DNA; flow cytometry; p21(WAF1 Cip1); p53

Indexed keywords

CYCLIN D1; CYCLIN DEPENDENT KINASE INHIBITOR; CYTOKERATIN; DNA; PROTEIN P21; PROTEIN P53; CYCLIN DEPENDENT KINASE; CYCLINE; KERATIN; ONCOPROTEIN; TUMOR MARKER;

ARTICLE; CELL CYCLE; DNA CONTENT; EPITHELIUM DYSPLASIA; EPITHELIUM HYPERPLASIA; FLOW CYTOMETRY; GENE OVEREXPRESSION; HUMAN; LARYNX MUCOSA; MALIGNANT TRANSFORMATION; MOLECULAR WEIGHT; PRIORITY JOURNAL; PROGNOSIS; SMOKING; SPAIN; SQUAMOUS CELL CARCINOMA; CELL TRANSFORMATION; CHEMISTRY; DRUG ANTAGONISM; EPITHELIUM; HYPERPLASIA; LARYNX DISORDER; LARYNX TUMOR; METABOLISM; PATHOLOGY; PRECANCER; TUMOR SUPPRESSOR GENE;

CARCINOMA, SQUAMOUS CELL; CELL TRANSFORMATION, NEOPLASTIC; CYCLIN D1; CYCLIN-DEPENDENT KINASES; CYCLINS; DNA, NEOPLASM; EPITHELIUM; GENES, P53; HUMANS; HYPERPLASIA; KERATINS; LARYNGEAL DISEASES; LARYNGEAL MUCOSA; LARYNGEAL NEOPLASMS; ONCOGENE PROTEINS; PRECANCEROUS CONDITIONS; TUMOR MARKERS, BIOLOGICAL;

EID: 0030611125     PISSN: 03655237     EISSN: None     Source Type: Journal    
DOI: 10.3109/00016489709124032     Document Type: Article

References (12)

1. Cuchi A, Bombi JA, Avellaneda R, Cardesa A, Traserra J. Precancerous lesions of the larynx: clinical and pathologic correlations and prognostic aspects. Head Neck 1994; 16: 545-9.
2. Mallofré C, Cardesa A, Campo E, et al. Expression of cytokeratins in squamous cell carcinomas of the larynx: Immunohistochemical analysis and correlation with prognostic factors. Pathol Res Pract 1993; 189: 275-82.
3. Kastan MB, Zhan Q, El-Deiry WS, et al. A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telanciectasia. Cell 1992; 71: 587-97.
4. Rodrigues NR, Rowan A, Smith MEF, et al. p53 mutations in colorectal cancer. Proc Natl Acad Sci USA 1990; 87: 7555-9.
5. Villuendas R, Piris MA, Algara P, et al. The expression of p53 protein in non-Hodgkin's lymphomas is not always dependent on p53 gene mutations. Blood 1993; 82: 3151-6.
6. Xu L, Chen Y.-T, Huvos AG, et al. Overexpression of p53 protein in squamous cell carcinomas of head and neck without apparent gene mutations. Diagn Mol Pathol 1994; 3: 83-92.
7. Nadal A, Campo E, Pinto J, et al. p53 expression in normal, dysplastic, and neoplastic laryngeal epithelium. Absence of a correlation with prognostic factors. J Pathol 1995; 175: 181-8.
8. Dolcetti R, Doglioni C, Maestro R, et al. p53 over-expression is an early event in the development of human squamous-cell carcinoma of the larynx: genetic and prognostic implications. Int J Cancer 1992; 52: 178-82.
9. Bennett WP, Colby TV, Travis WD, et al. p53 protein accumulates frequently in early bronchial neoplasia. Cancer Res 1993; 53: 4817-22.
10. Jares P, Fernández PL, Campo E, et al. PRAD-1/ Cyclin D1 gene amplification correlates with messenger RNA overexpression and tumor progression in human laryngeal carcinomas. Cancer Res 1994; 54: 4813-47.
11. WAF1. Cancer Res 1995; 55: 4536-9.
12. Fernández PL, Jares P, Nadal A, et al. p21 (WAF1) expression in laryngeal carcinomas: correlation with histological and clinical parameters. Mod Pathol 1996; 9: 101A.