Uptake of 169Yb complexes in normal and tumour cells: Influence of ligand and metabolic cell activity and stability of cellular association

Nuclear Medicine and Biology

Volumn 24, Issue 4, 1997, Pages 349-355

  Kampf, G ^a   Knop, G ^a   Franke, W G ^a   Bergmann, R ^b   Johannsen, B ^b  

^a UNIVERSITY HOSPITAL CARL GUSTAV CARUS   (Germany)

^b INSTITUTE OF ION BEAM PHYSICS AND MATERIALS RESEARCH   (Germany)

Author keywords

Biological transport; Label; Organometallic compounds; Tumour cells

Indexed keywords

PENTETATE YTTERBIUM YB 169; UNCLASSIFIED DRUG; YTTERBIUM 169 COMPLEX; LIGAND; RADIOISOTOPE; YTTERBIUM;

AGED; ANIMAL CELL; ARTICLE; CANCER CELL CULTURE; CELL CULTURE; CELL METABOLISM; CONTROLLED STUDY; DRUG UPTAKE; HUMAN; HUMAN CELL; ANIMAL; CELL LINE; HAMSTER; METABOLISM; NEOPLASM; TEMPERATURE;

ANIMALS; CELL LINE; CRICETINAE; HUMANS; LIGANDS; NEOPLASMS; RADIOISOTOPES; TEMPERATURE; YTTERBIUM;

EID: 0030611037     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-8051(97)00010-3     Document Type: Article

References (31)

1. rd World Congress of Nuclear Medicine and Biology, Vol. II, Paris, pp. 1772-1775.
2. rd World Congress of Nuclear Medicine and Biology, Vol. II, Paris, pp. 1768-1771.
3. Beyer G. J., Bergmann R., Kampf G., Mäding P., Rösch F. (1992) Simultaneous study of the biodistribution of radio-yttrium complexed with EDTMP and citrate ligands in tumour-bearing rats. Nucl. Med. Biol. 19, 201-203.
4. Bichel P. and Hanson H.H. (1972). The incorporation of 67Ga in normal and malignant cells and its dependence on growth rate. Br. J. Radiol 45, 182-184.
5. Brown D. H., Swartzendruber D. C., Carlton J. E., Byrd B. L., Hayes R. L. (1973) The isolation and characterization of gallium-binding granules from soft tissue tumors. Cancer Res. 33, 2063-2067.
6. 67Ga citrate. J. Nucl. Med. 10, 103-105.
7. 3-)-Zitratkomplexen für eine verbesserte Tumordarstellung. In: Radioaktive Isotope in Klinik und Forschung (Edited by Höfer R. and Bergmann H.), pp. 545-552. Gasteiner Internationales Symposium, 1984. Egermann, Wien.
8. Franke W. G., Schmiedel T., Grundmann A., Pöpel U., Pöpel Ute, Schomäcker K. and Gössel J.(1993) Erste klinische Erfahrungen bei der Tumordiagnostik mit radioaktiven Lanthanid-Komplexen. Nucl.-Med. 32, 188-193.
9. 18F]Fluoro-2-deoxy-D-glucose. Appl. Radiat. Isot. 47, 61-66.
10. Goeckeler W. F., Edwards B., Volkert W. A., Holmes R. A., Simon J. and Wilson D. (1987) Skeletal localization of Samarium-153 chelates: Potential therapeutic bone agents. J. Nucl. Med. 28, 495-504.
11. 67Ga in normal and malignant animal tissues. Cancer Res. 33, 3265-3272.
12. Hisada K. and Ando A. (1973) Radiolanthanides as promising tumor-scanning agents. J. Nucl. Med. 14, 615-617.
13. 111In for tumor localization. J. Nucl. Med. 10, 343.
14. 18F]-2-fluoro-2-deoxy-D-glucose in the isolated perfused rat heart. Isotopenpraxis 26, 4-6.
15. 186Re-HEDP as bone therapeutic radiopharmaceuticals. Nucl. Med. Biol. 14, 223-232.
16. King R. B. (Ed.) (1994) Encyclopedia of Inorganic Chemistry, Vol. 7, p. 1263. John Wiley & Sons, Chichester, UK.
17. King R. B. (Ed.) (1994) Encyclopedia of Inorganic Chemistry, Vol. 17, p. 3614. John Wiley & Sons, Chichester, UK.
18. Kriegel H. (1984) Biokinetics and metabolism of radiogallium. Nucl.-Med. 23, 53-57.
19. 18F] fluoroacetyl-D-glucosamine. Nucl. Med. Biol. 19, 747-752.
20. Kubota R., Yamada S., Kubota K., Ishiwata K., Tamahashi N. and Ido T. (1992) Intratumoral distribution of F-18-FDG in vivo: High accu-mulation in macrophages and granulation tissue studied by microauto-radiography. J. Nucl. Med. 33, 1972-1980.
21. Nassimbeni L. R., Wright M. R. W., Vanniekerk J. C. and McCallum P.A. (1979) Packing patterns in lanthanide-EDTA complexes-crystal and molecular structures of sodium triaqua(ethylenediaminetet-raacetato)dysprosate(III) pentahydrate and cesium diaqua(ethylenedia-minetetraacetato)ytterbate (III)trihydrate. Acta Crystallogr. B 35, 1341-1345.
22. 111In from labelled proteins and polymers. Nucl. Med. Biol. 21, 889-892.
23. Planas-Bohne F. and Duffield J. (1988) Factors influencing the uptake of iron and plutonium into cells. Int. J. Radiât. Biol. 53, 489-500.
24. Schomäcker K., Franke W.-G., Henke E., Fromm W. D., Maka G. and Beyer G. J. ( 1986) The influence of isotopic and nonisotopic carriers on the biodistribution and biokinetics of M3+-citrate complexes. Eur. J. Nud. Med. 11, 345-349.
25. Schomäcker K., Franke W.-G., Beyer G. J. and Münze R. (1986) Radiopharmacology of tumour-seeking trivalent metal complexes. In: Radioaktive Isotope in Klinik und Forschung (Edited by Höfer R. and Bergmann H.), pp. 397-401. Gasteiner Internationales Symposium. Egermann, Wien.
26. Schomäcker K., Franke W.-G., Gottschek A., Hartwig C., Richter K. and Beyer G. J. (1986) Physicochemical properties and biokinetics of tumoraffine metal (M)-ligand complexes In: Nuclear Medicine in Clinical Oncology (Edited by Winkler C.). Springer, Berlin, Heidelberg.
27. Schomäcker K., Franke W.-G., Mocker D., Münze R. and Beyer G. J. (1987) Zur Radiopharmakologie von M-Ligand-Komplexen. Radiobiol. Radiother. 28, 835-839.
28. Schomäcker K., Mocker D., Münze R. and Beyer G. J. (1988) Stabilities of lanthanide-protein-complexes. Appl. Radiât, Isot. 39, 261-264-
29. Schomäcker K., Franke W.-G., Jantsch K., Shukla S. K. and Limouris G. S. (1992) Der Einfluß von Ca-Diethylentriaminpentaacetat auf das Bioverhalten tumoraffiner Metallkomplexe. Nucl.-Med. 31, 242-248.
30. Singh A., Holmes R. A., Farhangi M., Volkert W. A., Williams A., Stringham L. M. and Ketring A. R. (1989) Human pharmacokinetics of samarium-153 EDTMP in metastatic cancer. J. Nucl. Med. 30, 1814-1818.
31. Tsan M. and Scheffel U. (1986) Mechanism of gallium-67 accumulation on tumours. J. Nucl. Med. 27, 1215-1219.