Radioligand binding and photoaftinity labelling studies show a direct interaction of phenothiazines at 5-HT3 receptors

Neuropharmacology

Volumn 36, Issue 4-5, 1997, Pages 665-670

  Lummis, S C R ^a   Baker, J ^a  

^a NONE

Author keywords

Chlorpromazine; GR65630; Ligand gated ion channel; m chlorophenylbiguanide; Radioligand binding

Indexed keywords

1 (3 CHLOROPHENYL)BIGUANIDE; 3 (5 METHYL 1H IMIDAZOL 4 YL) 1 (1 METHYL 1H INDOL 3 YL) 1 PROPANONE; CHLORPROMAZINE; FLUPHENAZINE; GRANISETRON; PERPHENAZINE; PHENOTHIAZINE DERIVATIVE; PROCHLORPERAZINE; RADIOLIGAND; SEROTONIN; SEROTONIN 3 AGONIST; SEROTONIN 3 ANTAGONIST; SEROTONIN 3 RECEPTOR; TRIFLUOPERAZINE; 1-(3-CHLOROPHENYL)BIGUANIDE; BIGUANIDE DERIVATIVE; IMIDAZOLE DERIVATIVE; INDOLE DERIVATIVE; SEROTONIN AGONIST; SEROTONIN ANTAGONIST; SEROTONIN RECEPTOR;

ANIMAL CELL; ARTICLE; CELL MEMBRANE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG BINDING SITE; DRUG MECHANISM; MOUSE; NEUROBLASTOMA CELL; NONHUMAN; PHOTOAFFINITY LABELING; PRIORITY JOURNAL; RECEPTOR BINDING; RECEPTOR DENSITY; AFFINITY LABELING; ANIMAL; BINDING COMPETITION; BRAIN TUMOR; CELL CULTURE; CHANNEL GATING; DRUG EFFECT; KINETICS; METABOLISM; NEUROBLASTOMA; PHOTOCHEMISTRY; RADIOASSAY;

AFFINITY LABELS; ANIMALS; BIGUANIDES; BINDING, COMPETITIVE; BRAIN NEOPLASMS; IMIDAZOLES; INDOLES; ION CHANNEL GATING; KINETICS; MICE; NEUROBLASTOMA; PHENOTHIAZINES; PHOTOCHEMISTRY; RADIOLIGAND ASSAY; RECEPTORS, SEROTONIN; SEROTONIN AGONISTS; SEROTONIN ANTAGONISTS; TUMOR CELLS, CULTURED;

EID: 0030610871     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(97)00054-3     Document Type: Article

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