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Volumn 25, Issue 6, 1997, Pages 725-731

Purification and 1H NMR spectroscopic characterization of phase II metabolites of tolfenamic acid

Author keywords

[No Author keywords available]

Indexed keywords

DRUG METABOLITE; GLUCURONIDE; NONSTEROID ANTIINFLAMMATORY AGENT; TOLFENAMIC ACID; ANTHRANILIC ACID DERIVATIVE;

EID: 0030610832     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (10)

References (9)
  • 1
    • 0022592875 scopus 로고
    • Assay of tolfenamic acid and its metabolites by liquid chromatography on dynamically modified silica: Application in pharmacokinetics
    • S. H. Hansen and S. B. Pedersen: Assay of tolfenamic acid and its metabolites by liquid chromatography on dynamically modified silica: application in pharmacokinetics. J. Pharm. Biomed. Anal., 4, 69-82 (1986).
    • (1986) J. Pharm. Biomed. Anal. , vol.4 , pp. 69-82
    • Hansen, S.H.1    Pedersen, S.B.2
  • 3
    • 0031051131 scopus 로고    scopus 로고
    • Directly-coupled 800 MHz HPLC-NMR spectroscopy of urine and its application in the identification of the major phase II metabolites of tolfenamic acid
    • in press
    • U. G. Sidelmann, U. Braumann, M. Hofmann, M. Spraul, J. C. Lindon, J. K. Nicholson, and S. H. Hansen: Directly-coupled 800 MHz HPLC-NMR spectroscopy of urine and its application in the identification of the major phase II metabolites of tolfenamic acid. Anal. Chem., in press.
    • Anal. Chem.
    • Sidelmann, U.G.1    Braumann, U.2    Hofmann, M.3    Spraul, M.4    Lindon, J.C.5    Nicholson, J.K.6    Hansen, S.H.7
  • 4
    • 0023887138 scopus 로고
    • Solid phase extraction chromatography and NMR spectrometry (SPEC-NMR) for the rapid identification of drug metabolites in urine
    • I. D. Wilson and J. K. Nicholson. Solid phase extraction chromatography and NMR spectrometry (SPEC-NMR) for the rapid identification of drug metabolites in urine. J. Pharm. Biomed. Anal., 6, 151-165 (1988).
    • (1988) J. Pharm. Biomed. Anal. , vol.6 , pp. 151-165
    • Wilson, I.D.1    Nicholson, J.K.2
  • 5
    • 0023628652 scopus 로고
    • Solid-phase extraction and nuclear magnetic resonance spectrometry for the identification and isolation of drug metabolites in urine
    • I. D. Wilson and J. K. Nicholson: Solid-phase extraction and nuclear magnetic resonance spectrometry for the identification and isolation of drug metabolites in urine. Anal. Chem., 59, 2830-2832 (1987).
    • (1987) Anal. Chem. , vol.59 , pp. 2830-2832
    • Wilson, I.D.1    Nicholson, J.K.2
  • 7
    • 0017839704 scopus 로고
    • Metabolism of pentachlorophenol in vivo and in vitro
    • U. G. Ahlborg, K. Larsson, and T. Thunberg. Metabolism of pentachlorophenol in vivo and in vitro. Arch. Toxicol. 40, 45-53 (1978).
    • (1978) Arch. Toxicol. , vol.40 , pp. 45-53
    • Ahlborg, U.G.1    Larsson, K.2    Thunberg, T.3
  • 8
    • 0019779039 scopus 로고
    • Metabolism of dichlorophenyles by highly purified isozymes of rat liver cytochrome
    • L. S. Kaminsky, M. W. Kennedy, S. M. Adams, and F. P. Guengerich,: Metabolism of dichlorophenyles by highly purified isozymes of rat liver cytochrome. Biochem. 20, 7379-7384 (1981).
    • (1981) Biochem. , vol.20 , pp. 7379-7384
    • Kaminsky, L.S.1    Kennedy, M.W.2    Adams, S.M.3    Guengerich, F.P.4
  • 9
    • 0028867076 scopus 로고
    • Identification of the positional isomers of 2- Fluorobenzoic acid 1-O-acyl glucuronides by directly coupled HPLC-NMR
    • U. G. Sidelmann, C. Gavaghan, H. A. J. Carless, R. D. Farrant, J. C. Lindon, I. D. Wilson, and J. K. Nicholson: Identification of the positional isomers of 2-fluorobenzoic acid 1-O-acyl glucuronides by directly coupled HPLC-NMR. Anal. Chem. 67, 3401-3404 (1995).
    • (1995) Anal. Chem. , vol.67 , pp. 3401-3404
    • Sidelmann, U.G.1    Gavaghan, C.2    Carless, H.A.J.3    Farrant, R.D.4    Lindon, J.C.5    Wilson, I.D.6    Nicholson, J.K.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.