APOE ε4 allele frequency in Alzheimer's disease and vascular dementia in the Spanish population

Annals of the New York Academy of Sciences

Volumn 826, Issue , 1997, Pages 452-455

  Beyer, Katrin ^a   Lao, José Ignacio ^a   Fernández Novoa, Lucia ^a   Alvarez, Xosé Antón ^a   Sellers, Maria Angeles ^a   Cacabelos, Ramon ^a  

^a Centro de Investigacion Biomedica EuroEspes   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN E4; APOLIPOPROTEIN E;

AGED; ALLELE; ALZHEIMER DISEASE; COGNITION; CONFERENCE PAPER; CONTROLLED STUDY; EXON; GENE FREQUENCY; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MULTIINFARCT DEMENTIA; ONSET AGE; RISK FACTOR; SPAIN; ARTICLE; FEMALE; GENETICS; MALE; MIDDLE AGED;

AGED; AGED, 80 AND OVER; ALLELES; ALZHEIMER DISEASE; APOLIPOPROTEINS E; DEMENTIA, VASCULAR; FEMALE; GENE FREQUENCY; HUMANS; MALE; MIDDLE AGED; SPAIN;

EID: 0030610827     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1997.tb48502.x     Document Type: Conference Paper

References (7)

1. WEISGRABER, K. H. 1994. Apolipoprotein E: Structure-function relationship. Adv. Prot. Chem. 45: 249-320.
2. ST. CLAIR, D. et al. 1995. Apolipoprotein E allele ε4 is a risk factor for familial and sporadic presenile Alzheimer's disease in both homozygote and heterozygote carriers. J. Med. Genet. 32: 642-644.
3. CACABELOS, R. et al. 1996. Genetic testing in Alzheimer's disease: APOE genotyping and ethiopathogenic factors. Meth. Find. Exp. Clin. Pharmacol. 18(Suppl. A): 161-179.
4. BASUN, H. et al. 1995. Apolipoprotein E ε4 allele and disease progression in patients with late-onset Alzheimer's disease. Neurosci. Lett. 183: 32-34.
5. HALLMAN, D. M. et al. 1991. The apolipoprotein E polymorphism: A comparison of allele frequencies and effects in nine populations. Am. J. Hum. Genet. 49: 338-349.
6. SLOOTER, A. J. et al. 1996. APOE genotyping in differential diagnosis of Alzheimer's disease. Lancet 348: 334.
7. CACABELOS, R., B. RODRÍGUEZ, C. CARRERA, K. BEYER, J. I. LAO & M. A. SELLERS. Behavioral changes associated with different APOE genotypes in dementia. Alzheimer's Dis. Assoc. Dis. In press.