Epidura bolus clonidine/morphine versus epidural patient-controlled bupivacaine/sufentanil: Quality of postoperative analgesia and cost- identification analysis

Anesthesia and Analgesia

Volumn 85, Issue 4, 1997, Pages 864-869

  Rockemann, Michael G ^a   Seeling, Wulf ^a   Duschek, Sonja ^a   Reinelt, Helmut ^a   Steffen, Peter ^a   Georgieff, Michael ^a  

^a UNIVERSITY OF ULM   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BUPIVACAINE; CLONIDINE; MORPHINE; SUFENTANIL; ANALGESIC AGENT;

ABDOMINAL SURGERY; ADULT; AGED; ARTERIAL PRESSURE; ARTICLE; BOLUS INJECTION; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; COST; COUGHING; DRUG MIXTURE; EPIDURAL DRUG ADMINISTRATION; FEMALE; HEART RATE; HUMAN; HYPOTENSION; MAJOR CLINICAL STUDY; MALE; PAIN; PATIENT CONTROLLED ANALGESIA; POSTOPERATIVE ANALGESIA; POSTOPERATIVE PAIN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; COMPARATIVE STUDY; ECONOMICS; EPIDURAL ANESTHESIA; HEALTH CARE COST; MIDDLE AGED;

ADULT; AGED; ANALGESIA, EPIDURAL; ANALGESIA, PATIENT-CONTROLLED; ANALGESICS; BUPIVACAINE; CLONIDINE; FEMALE; HEALTH CARE COSTS; HUMANS; MALE; MIDDLE AGED; MORPHINE; PAIN, POSTOPERATIVE; SUFENTANIL;

EID: 0030610752     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000539-199710000-00028     Document Type: Article

References (18)

1. Donovan BD. Patient attitudes to postoperative pain relief. Anaesth Intensive Care 1983;11:125-9.
2. Ballantyne JC, Carr DB, Chalmers TC, et al. Postoperative patient-controlled analgesia: meta-analyses of initial randomized control trials. J Clin Anesth 1993;5:182-93.
3. Rockemann MG, Seeling W, Schirmer U, et al. Epidural and intravenous patient-controlled analgesia after intraabdominal surgery: a comparison. Anaesth Intensivmed 1996;37:332-8.
4. Rockemann MG, Seeling W, Konietzko I, Georgieff M. Intravenöse und epidurale patientenkontrollierte Analgesie (PCA): Wirtschaftlichkeit [abstract]. Anaesthesiol Intensivmed Notfallmed Schmerzther 1997;32:S180.
5. Roerig SC, Lei S, Kitto K, et al. Spinal interactions between opioid and noradrenergic agonists in mice: multiplicativity involves delta and alpha-2 receptors. J Pharmacol Exp Ther 1992; 262:365-74.
6. Altman DG. Statistics and ethics in medical research. III. How large a sample? BMJ 1980;281:1336-8.
7. Mössner J. Epidemiology of chronic pancreatitis. In: Beger HG, Büchler M, Malfertheiner P, eds. Standards in pancreatic surgery. Berlin: Springer, 1993:263-71.
8. Büchler M, Weihe E, Friess H, et al. Changes in peptidergic innervation in chronic pancreatits. Pancreas 1992;7:183-92.
9. Patel SS, Dunn CJ, Bryson HM. Epidural clonidine: a review of its pharmacology and efficacy in the management of pain during labour and postoperative and intractable pain. CNS Drugs 1996;6:474-97.
10. Castro MI, Eisenach JC. Pharmacokinetics and dynamics of intravenous, intrathecal, and epidural clonidine in sheep. Anesthesiology 1989;71:418-25.
11. Wilkins AJ, Jenkins WJ, Steiner JA. Efficacy of clonidine in treatment of alcohol withdrawal state. Psychopharmacology 1983;81:78-80.
12. Rockemann MG, Seeling W, Brinkmann A, et al. Analgesic and hemodynamic effects of epidural clonidine, clonidine/ morphine and morphine after pancreatic surgery: a double blind study. Anesth Analg 1995;80:869-74.
13. Dahl JB, Rosenberg J, Hansen BL, et al. Differential analgesic effects of low-dose epidural morphine and morphine-bupivacaine at rest and during mobilization after major abdominal surgery. Anesth Analg 1992;74:362-5.
14. Germain H, Néron A, Lomssy A. Analgesic effect of epidural clonidine. In: Dubner R, Gebhart GF, Bond MR, eds. Proceedings of the Vth World Congress on Pain, Hamburg (Germany), 1987. New York: Elsevier, 1988:472-6.
15. Klimscha W, Chiari A, Krafft P, et al. Hemodynamic and analgesic effects of clonidine added repetitively to continuous epidural and spinal blocks. Anesth Analg 1995;80:322-7.
16. Colwell CW Jr, Morris BA. Patient-controlled analgesia compared with intramuscular injection of analgesics for the management of pain after an orthopedic procedure. J Bone Joint Surg Am 1995;77:726-33.
17. Smith CV, Rayburn WF, Karaiskakis PT, et al. Comparison of patient-controlled analgesia and epidural morphine for post-cesarean pain and recovery. J Reprod Med 1991;36:430-4.
18. Cohen SE, Subak LL, Brose WG, Halpern J. Analgesia after cesarean delivery: patient evaluations and costs of five opioid techniques. Reg Anesth 1991;16:141-9.