Conformational selectivity of HIVE-1 protease cleavage of X-pro peptide bonds and its implications

Journal of Biological Chemistry

Volumn 272, Issue 25, 1997, Pages 15603-15606

  Vance, Joseph E ^a   LeBlanc, Darryl A ^a   Wingfield, Paul ^b   London, Robert E ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^b NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEINASE; CARRIER PROTEIN; GAG PROTEIN; ISOMERASE; PEPTIDYLPROLYL ISOMERASE; PROLINE; RECOMBINANT PROTEIN; TYROSINE;

ARTICLE; CONFORMATIONAL TRANSITION; CRYSTALLOGRAPHY; DNA CLEAVAGE; ENZYME CONFORMATION; ENZYME SPECIFICITY; ENZYME SUBSTRATE; HUMAN IMMUNODEFICIENCY VIRUS 1; HYDROLYSIS; ISOMERISM; NONHUMAN; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN FOLDING; CONSENSUS SEQUENCE; HUMAN; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN BINDING; PROTEIN CONFORMATION; SPECTROFLUOROMETRY; STRUCTURE ACTIVITY RELATION;

AMINO ACID ISOMERASES; CARRIER PROTEINS; CONSENSUS SEQUENCE; GENE PRODUCTS, GAG; HIV PROTEASE; HUMANS; ISOMERISM; MAGNETIC RESONANCE SPECTROSCOPY; PEPTIDYLPROLYL ISOMERASE; PROLINE; PROTEIN BINDING; PROTEIN CONFORMATION; RECOMBINANT PROTEINS; SPECTROMETRY, FLUORESCENCE; STRUCTURE-ACTIVITY RELATIONSHIP; TYROSINE;

EID: 0030610548     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.25.15603     Document Type: Article

References (37)

1. Debouck, C., and Metcalf, B. W. (1990) Drug Dev. Res 21, 1-17
2. Lin, L. N., and Brandts, J. F. (1979) Biochemistry 18, 43-47
3. Lin, L. N., and Brandts, J. F. (1979) Biochemistry 18, 5037-5042
4. King, G. F., Middlehurst, C. R., and Kuchel, P. W. (1986) Biochemistry 25, 1054-1062
5. Vanhoof, G., Goossens, F., DeMeester, I., Hendriks, D., and Scharpe, S. (1995) FASEB J. 9, 736-744
6. Lin, L. N., and Brandts, J. F. (1983) Biochemistry 22(3), 553-559
7. Lin, L. N., and Brandts, J. F. (1983) Biochemistry 22, 4480-4485
8. Fischer, G., Heins, J., and Barth, A. (1983) Biochim. Biophys. Acta 742, 452-462
9. Fischer, G., Bang, H., Berger, E., and Schellenberger, A. (1984) Biochim. Biophys. Acta 791, 87-97
10. Fischer, G., Bang, H., and Mech, C. (1984) Biomed. Biochim. Acta 43, 1101-1111
11. Slee, D. H., Laslo, K. L., Elder, J. H., Ollmann, I. R., Gustchina, A., Kervinen, J., Zdanov, A., Wlodawer, A., and Wong, C.-H. (1995) J. Am. Chem. Soc. 117, 11867-11878
12. Baldwin, E. T., Bhat, T. N., Gulnik, S., Liu, B., Topol, I. A., Kiso, Y., Mimoto, T., Mitsuya H., and Erickson, J. W. (1995) Structure 3, 581-590
13. Charlton, P. A., Young, D. W., Birdsall, B., Feeney, J., and Roberts, G. C. K. (1979) J. Chem. Soc. Chem. Comm., 922-924
14. Luban, J., Bossolt, K. L., Franke, E. K., Kalpana, G. V., and Goff, S. P. (1993) Cell 73, 1067-1078
15. Thali, M., Bukovsky, A., Kondo, E., Rosenwirth, B., Walsh, C. T., Sodroski, J., and Gottlinger, H. G. (1994) Nature 372, 363-365
16. Franke, E. K., Yuan, H. E., and Luban, J. (1994) Nature 372, 359-362
17. Braaten, D., Franke, E. K., and Luban, J. (1996) J. Virol. 70, 3551-3560
18. London, R. E., Davis, D. G., Vavrek, R. J., Stewart, J. M., and Handschumacher, R. E. (1990) Biochemistry 29, 10298-10302
19. Morris, G. A., and Freeman, R. (1978) J. Magn. Reson. 29, 433-462
20. Perrin, C. L., and Engler, R. E. (1990) J. Magn. Reson. 90, 363-369
21. Kofron, J. L., Kuzmic, P., Kishore, V., Colon-Bonilla, E., and Rich, D. H. (1991) Biochemistry 30, 6127-6134
22. Matayoshi, E. D., Wang, G. T., Krafft, G. A., and Erickson, J. (1990) Science 247, 954-958
23. Moore, M. L., Bryan, W. M., Fakhoury, S. A., Magaard, V. W., Huffman, W. F., Dayton, B. D., Meek, T. D., Hyland, L., Dreyer, G. B., Metcalf, B. W., Strickler, J. E., Gorniak, J. G., and Debouck, C. (1989) Biochem. Biophys. Res. Commun. 159, 420-425
24. Broadhurst, A. V., Roberts, N. A., Ritchie, A. J., Handa, B. K., and Kay, C. (1991) Anal. Biochem. 193, 280-286
25. Wang, G. T., Matayoshi, E., Huffaker, H. J., and Krafft, G. A. (1990) Tetrahedron Lett. 31, 6493-6496
26. Geohegan, K. F., Spencer, R. W., Danley, D. E., Contillo, L. G., Jr., and Andrews, G. C. (1990) FEBS Lett. 262, 119-122
27. Sarubbi, E., Nolli, M. L., Andronico, F., Stella, S., Saddler, G., Selva, E., Siccardi, A., and Denaro, M. (1991) FEBS Lett. 279, 265-269
28. Krafft, G. A., and Wang, G. T. (1993) ACS Symp. Ser. 538, 183-195
29. Anjuere, F., Monsigny, M., LeLievre, Y., and Mayer, R. (1993) Biochem. J. 291, 869-873
30. Knight, M., Ito, Y., Chandrasekhar, B., Takahashi, K., and Mukherjee, A. B. (1995) in Modern Countercurrent Chromatography (Conway, W. D., ed) ACS Symposium Series, Vol. 593, pp. 111-118, American Chemical Society, Washington, D. C.
31. Tyagi, S. C., Simon, S. R., and Carter, C. A. (1994) Biochem. Cell Biol. 72, 175-181
32. Holzman, T. F., Kohlbrenner, W. E., Weigl, D., Rittenhouse, J., Kempf, D., and Erickson, J. (1991) J. Biol. Chem 266, 19217-19220
33. Kuzmic, P., Garcia Echeverria, C., and Rich, D. H. (1993) Biochem. Biophys. Res. Commun 194(1), 301-305
34. Tomasselli, A. G., Mildner, A. M., Rothroch, D. J., Sarcich, J. L., Lull, J., Leone, J., and Heinrikson, R. L. (1995) in Aspartic Proteinases: Structure, Functtion, Biology, and Biomedical Implications (Takahashi, K., ed) pp. 387-398, Plenum Press, New York
35. Petit, S. C., Moody, M. D., Wehbie, R. S., Kaplan, A. H., Nantermet, P. V., Klein, C. A., and Swanstrom, R. (1994) J. Virol. 68, 8017-8027
36. Rose, J. R., Salto, R., and Craik, C. S., (1993) J. Biol. Chem. 268, 11939-11945
37. Navia, M. A., Fitzgerald, P. M. D., McKeever, B. M., Leu, C.-T., Heimbach, J. C., Herber, W. K., Sigal, I. S., Darke, P. L., and Springer, J. P. (1989) Nature 337, 615-620