메뉴 건너뛰기




Volumn 29, Issue 1-2, 1997, Pages 235-260

Mitogenic actions of peroxisome proliferators: Involvement of protein kinase C and tumor necrosis factor α

Author keywords

[No Author keywords available]

Indexed keywords

2 ETHYLHEXANOL; BROXURIDINE; CYANIDE; KETONE BODY; LACTATE DEHYDROGENASE; LONG CHAIN FATTY ACID COENZYME A LIGASE; MITOGENIC AGENT; NAFENOPIN; OXYGEN; PEROXISOME PROLIFERATOR; PIRINIXIC ACID; PROTEIN KINASE C; TOMELUKAST; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA ANTIBODY; CARCINOGEN;

EID: 0030610416     PISSN: 03602532     EISSN: None     Source Type: Journal    
DOI: 10.3109/03602539709037584     Document Type: Conference Paper
Times cited : (7)

References (71)
  • 1
    • 0023522829 scopus 로고
    • The effect of peroxisome proliferators on microsomal, peroxisomal, and mitochondrial enzyme activities in the liver and kidney
    • J. M. Hawkins, W. E. Jones, F. W. Bonner, and G. G. Gibson, The effect of peroxisome proliferators on microsomal, peroxisomal, and mitochondrial enzyme activities in the liver and kidney, Drug Metab. Dispos., 18, 441-515 (1987).
    • (1987) Drug Metab. Dispos. , vol.18 , pp. 441-515
    • Hawkins, J.M.1    Jones, W.E.2    Bonner, F.W.3    Gibson, G.G.4
  • 2
    • 0021051308 scopus 로고
    • Carcinogenesis by hepatic peroxisome proliferators: Evaluation of the risk of hypolipidemic drugs and industrial plastciizers to humans
    • J. K. Reddy and N. D. Lalwani, Carcinogenesis by hepatic peroxisome proliferators: Evaluation of the risk of hypolipidemic drugs and industrial plastciizers to humans, Crit. Rev. Toxicol., 12, 1-58 (1983).
    • (1983) Crit. Rev. Toxicol. , vol.12 , pp. 1-58
    • Reddy, J.K.1    Lalwani, N.D.2
  • 3
    • 0025816839 scopus 로고
    • Hepatocellular DNA synthesis in rats given peroxisome proliferating agents: Comparison of WY-14,643 to clofibric acid, nafenopin and LY171883
    • P. I. Eacho, T. L. Lanier, and C. A. Brodhecker, Hepatocellular DNA synthesis in rats given peroxisome proliferating agents: Comparison of WY-14,643 to clofibric acid, nafenopin and LY171883, Carcinogenesis, 12, 1557-1561 (1991).
    • (1991) Carcinogenesis , vol.12 , pp. 1557-1561
    • Eacho, P.I.1    Lanier, T.L.2    Brodhecker, C.A.3
  • 4
    • 0024241608 scopus 로고
    • Relationship of hepatic peroxisome proliferation and replicative DNA synthesis to the hepatocarcinogenicity of the peroxisome proliferators di(2-ethylhexyl)phthalate and [4-chloro-6-(2,3-xylidino)-2-pyrimidinylthio]acetic acid (WY-14,643) in rats
    • D. S. Marsman, R. C. Cattley, J. G. Conway, and J. A. Popp, Relationship of hepatic peroxisome proliferation and replicative DNA synthesis to the hepatocarcinogenicity of the peroxisome proliferators di(2-ethylhexyl)phthalate and [4-chloro-6-(2,3-xylidino)-2-pyrimidinylthio]acetic acid (WY-14,643) in rats, Cancer Res., 48, 6739-6744 (1988).
    • (1988) Cancer Res. , vol.48 , pp. 6739-6744
    • Marsman, D.S.1    Cattley, R.C.2    Conway, J.G.3    Popp, J.A.4
  • 5
    • 0024430314 scopus 로고
    • Oxidative DNA damage caused by persistent peroxisome proliferation: Its role in hepatocarcinogenesis
    • J. K. Reddy and M. S. Roa, Oxidative DNA damage caused by persistent peroxisome proliferation: Its role in hepatocarcinogenesis, Mutat. Res., 214, 63-68 (1989).
    • (1989) Mutat. Res. , vol.214 , pp. 63-68
    • Reddy, J.K.1    Roa, M.S.2
  • 6
    • 0020483106 scopus 로고
    • Evidence that peroxisomal acyl-CoA synthetase is located at the cytoplasmic side of the peroxisomal membrane
    • G. P. Mannaerts, P. Van Velhoven, A. Van Broekhoven, G. Vandebroek, and L. J. Debeer, Evidence that peroxisomal acyl-CoA synthetase is located at the cytoplasmic side of the peroxisomal membrane, Biochem. J., 20, 17-23 (1982).
    • (1982) Biochem. J. , vol.20 , pp. 17-23
    • Mannaerts, G.P.1    Van Velhoven, P.2    Van Broekhoven, A.3    Vandebroek, G.4    Debeer, L.J.5
  • 7
    • 0024521714 scopus 로고
    • Relationship of oxidative damage to the hepatocarcinogenicity of the peroxisome proliferators di(2-ethylhexyl)phthalate and [4-chloro-6-(2,3-xylidino)-2-pyrimidinylthio]acetic acid (WY-14,643)
    • J. G. Conway, K. E. Tomaszewski, M. J. Olsen, R. C. Cattely, D. S. Marsman, and J. A. Popp, Relationship of oxidative damage to the hepatocarcinogenicity of the peroxisome proliferators di(2-ethylhexyl)phthalate and [4-chloro-6-(2,3-xylidino)-2-pyrimidinylthio]acetic acid (WY-14,643), Carcinogenesis, 10, 513-519 (1989).
    • (1989) Carcinogenesis , vol.10 , pp. 513-519
    • Conway, J.G.1    Tomaszewski, K.E.2    Olsen, M.J.3    Cattely, R.C.4    Marsman, D.S.5    Popp, J.A.6
  • 8
    • 0024323931 scopus 로고
    • Formation of 8-hydroxydeoxyguanosine in liver DNA of rats following long-term exposure to a peroxisome proliferator
    • H. Kasai, Y. Okada, S. Nishimura, M. S. Roa, and J. K. Reddy, Formation of 8-hydroxydeoxyguanosine in liver DNA of rats following long-term exposure to a peroxisome proliferator. Cancer Res., 49, 2603-2605 (1989).
    • (1989) Cancer Res. , vol.49 , pp. 2603-2605
    • Kasai, H.1    Okada, Y.2    Nishimura, S.3    Roa, M.S.4    Reddy, J.K.5
  • 9
    • 0342704171 scopus 로고
    • Production of 8-hydroxydeoxyguanosine in rodent liver by the administration of peroxisome proliferators
    • G. Gordon and B. Lake, eds., Taylor and Francis, London
    • A. Takagi, K. Sai, T. Umemura, R. Hasegawa, and Y. Kurokawa, Production of 8-hydroxydeoxyguanosine in rodent liver by the administration of peroxisome proliferators, in Peroxisomes: Biology and Importance in Toxicology and Medicine (G. Gordon and B. Lake, eds.), Taylor and Francis, London, 1983.
    • (1983) Peroxisomes: Biology and Importance in Toxicology and Medicine
    • Takagi, A.1    Sai, K.2    Umemura, T.3    Hasegawa, R.4    Kurokawa, Y.5
  • 10
    • 0028987876 scopus 로고
    • Mechanisms of hepatocarcinogenicity of peroxisome-proliferating drugs and cheimcals
    • B. G. Lake, Mechanisms of hepatocarcinogenicity of peroxisome-proliferating drugs and cheimcals, Annu. Rev. Pharmacol. Toxicol., 35, 483-507 (1995).
    • (1995) Annu. Rev. Pharmacol. Toxicol. , vol.35 , pp. 483-507
    • Lake, B.G.1
  • 11
    • 0001408791 scopus 로고
    • P. D. Boyer, ed., Academic Press, New York
    • P. Nicholls and G. R. Schonbaum, in Catalases (P. D. Boyer, ed.), Academic Press, New York, 1963, pp. 147-225.
    • (1963) Catalases , pp. 147-225
    • Nicholls, P.1    Schonbaum, G.R.2
  • 15
    • 0021139109 scopus 로고
    • Effect of di(2-ethylhexyl)phthalate on DNA repair and lipid peroxidation in rat hepatocytes and on metabolic cooperation in Chinese hamster V-79 cells
    • D. J. Kornburst, T. R. Barfknecht, P. Ingram, and J. D. Shelburne, Effect of di(2-ethylhexyl)phthalate on DNA repair and lipid peroxidation in rat hepatocytes and on metabolic cooperation in Chinese hamster V-79 cells, J. Toxicol. Environ. Health, 13, 99-116 (1984).
    • (1984) J. Toxicol. Environ. Health , vol.13 , pp. 99-116
    • Kornburst, D.J.1    Barfknecht, T.R.2    Ingram, P.3    Shelburne, J.D.4
  • 16
    • 0027304198 scopus 로고
    • Comparison of the acute and chronic mitogenic effects of the peroxisome proliferators methylclofenapate and clofibric acid in rat liver
    • N. C. Barrass, R. J. Price, B. G. Lake, and T. C. Orton, Comparison of the acute and chronic mitogenic effects of the peroxisome proliferators methylclofenapate and clofibric acid in rat liver, Carcinogenesis, 14, 1451-1456 (1993).
    • (1993) Carcinogenesis , vol.14 , pp. 1451-1456
    • Barrass, N.C.1    Price, R.J.2    Lake, B.G.3    Orton, T.C.4
  • 17
    • 0027092379 scopus 로고
    • Comparison of the effects of nafenopin on hepatic peroxisome proliferation and replicative DNA synthesis in the rat and Syrian hamster
    • R. J. Price, J. G. Evans, and B. G. Lake, Comparison of the effects of nafenopin on hepatic peroxisome proliferation and replicative DNA synthesis in the rat and Syrian hamster, Food Chem. Toxicol., 30, 937-944 (1992).
    • (1992) Food Chem. Toxicol. , vol.30 , pp. 937-944
    • Price, R.J.1    Evans, J.G.2    Lake, B.G.3
  • 18
    • 0025832995 scopus 로고
    • Age-related susceptibility to the carcinogenic effect of the peroxisome proliferator WY-14,643 in rat liver
    • R. C. Cattley, D. S. Marsman, and J. A. Popp, Age-related susceptibility to the carcinogenic effect of the peroxisome proliferator WY-14,643 in rat liver, Carcinogenesis, 12, 469-473 (1991).
    • (1991) Carcinogenesis , vol.12 , pp. 469-473
    • Cattley, R.C.1    Marsman, D.S.2    Popp, J.A.3
  • 19
    • 0026014061 scopus 로고
    • Increased susceptibility of aged rats to hepatocarcinogenesis by the peroxisome proliferator nafenopin and the possible involvement of altered liver foci occurring spontaneously
    • B. Kraupp-Grasl, W. Huber, H. Taper, and R. Schulte-Hermann, Increased susceptibility of aged rats to hepatocarcinogenesis by the peroxisome proliferator nafenopin and the possible involvement of altered liver foci occurring spontaneously, Cancer Res., 51, 666-671 (1991).
    • (1991) Cancer Res. , vol.51 , pp. 666-671
    • Kraupp-Grasl, B.1    Huber, W.2    Taper, H.3    Schulte-Hermann, R.4
  • 20
    • 0028173749 scopus 로고
    • Biological potential of basophilic hepatocellular foci and hepatic adenoma induced by the peroxisome proliferator, WY-14,643
    • D. S. Marsman and J. A. Popp, Biological potential of basophilic hepatocellular foci and hepatic adenoma induced by the peroxisome proliferator, WY-14,643, Carcinogenesis, 15, 111-117 (1994).
    • (1994) Carcinogenesis , vol.15 , pp. 111-117
    • Marsman, D.S.1    Popp, J.A.2
  • 21
    • 0025195341 scopus 로고
    • Oxygen-dependent hepatotoxicity to ethylhexanol in the perfused rat liver: Mitochondria as a site of action
    • B. J. Keller, H. Yamanaka, D. Liang, F. C. Kauffman, and R. G. Thurman, Oxygen-dependent hepatotoxicity to ethylhexanol in the perfused rat liver: Mitochondria as a site of action, J. Pharmacol. Exp. Ther., 252, 1355-1360 (1990).
    • (1990) J. Pharmacol. Exp. Ther. , vol.252 , pp. 1355-1360
    • Keller, B.J.1    Yamanaka, H.2    Liang, D.3    Kauffman, F.C.4    Thurman, R.G.5
  • 22
    • 0026697553 scopus 로고
    • Several nongenotoxic carcinogens uncouple mitochondrial oxidative phosphorylation
    • B. J. Keller, D. S. Marsman, J. A. Popp, and R. G. Thurman, Several nongenotoxic carcinogens uncouple mitochondrial oxidative phosphorylation, Biochim. Biophys. Acta, 1102, 237-244 (1992).
    • (1992) Biochim. Biophys. Acta , vol.1102 , pp. 237-244
    • Keller, B.J.1    Marsman, D.S.2    Popp, J.A.3    Thurman, R.G.4
  • 24
    • 0019992090 scopus 로고
    • Bleb formation in hepatocytes during drug metabolism caused by disturbance in thiol and calcium ion homeostasis
    • S. A. Jewell, G. Bellomo, T. Hjordis, S. Orrenius, and M. T. Smith, Bleb formation in hepatocytes during drug metabolism caused by disturbance in thiol and calcium ion homeostasis, Science, 217, 1257-1259 (1982).
    • (1982) Science , vol.217 , pp. 1257-1259
    • Jewell, S.A.1    Bellomo, G.2    Hjordis, T.3    Orrenius, S.4    Smith, M.T.5
  • 25
    • 0029875098 scopus 로고    scopus 로고
    • Paradoxical increase in peroxisomal cyanide-insensitive respiration following dietary exposure to WY-14,634 in the perfused liver
    • H. K. Bojes, P. J. Sausen, R. C. Cattley, B. J. Keller, and R. G. Thurman, Paradoxical increase in peroxisomal cyanide-insensitive respiration following dietary exposure to WY-14,634 in the perfused liver, Toxicol. Appl. Pharmacol., 137, 202-209 (1996).
    • (1996) Toxicol. Appl. Pharmacol. , vol.137 , pp. 202-209
    • Bojes, H.K.1    Sausen, P.J.2    Cattley, R.C.3    Keller, B.J.4    Thurman, R.G.5
  • 26
    • 0014589474 scopus 로고
    • Mixed function oxidation in perfused rat liver. The effect of aminopyrine on oxygen uptake
    • R. G. Thurman and R. Scholz, Mixed function oxidation in perfused rat liver. The effect of aminopyrine on oxygen uptake, Eur. J. Biochern., 10, 459-467 (1969).
    • (1969) Eur. J. Biochern. , vol.10 , pp. 459-467
    • Thurman, R.G.1    Scholz, R.2
  • 27
    • 0021227676 scopus 로고
    • The role of protein kinase C in cell surface signal transduction and tumor promotion
    • Y. Nishizuka, The role of protein kinase C in cell surface signal transduction and tumor promotion, Nature, 308, 693-698 (1984).
    • (1984) Nature , vol.308 , pp. 693-698
    • Nishizuka, Y.1
  • 28
    • 0023764824 scopus 로고
    • The molecular heterogeneity of protein kinase C and its implications for cellular regulation
    • Y. Nishizuka, The molecular heterogeneity of protein kinase C and its implications for cellular regulation, Nature, 334, 661-665 (1988).
    • (1988) Nature , vol.334 , pp. 661-665
    • Nishizuka, Y.1
  • 29
    • 0028241634 scopus 로고
    • Peroxisomal proliferators inhibit acyl CoA synthetase and stimulate protein kinase C in vivo
    • H. K. Bojes and R. G. Thurman, Peroxisomal proliferators inhibit acyl CoA synthetase and stimulate protein kinase C in vivo, Toxicol. Appl. Pharmacol., 126, 233-239 (1994).
    • (1994) Toxicol. Appl. Pharmacol. , vol.126 , pp. 233-239
    • Bojes, H.K.1    Thurman, R.G.2
  • 32
    • 0022355236 scopus 로고
    • Time and dose-response study of the effects on the rates of the plasticizer di(2-ethylhexyl)phthalate
    • F. E. Mitchell, S. C. Price, R. C. Hinton, P. Grasso, and J. W. Bridges, Time and dose-response study of the effects on the rates of the plasticizer di(2-ethylhexyl)phthalate, Toxol. Appl. Pharmacol., 81, 371-392 (1985).
    • (1985) Toxol. Appl. Pharmacol. , vol.81 , pp. 371-392
    • Mitchell, F.E.1    Price, S.C.2    Hinton, R.C.3    Grasso, P.4    Bridges, J.W.5
  • 34
    • 0025695105 scopus 로고
    • Changes in hepatic lipid metabolism associated with lipid accumulation and its reversal in rats given peroxisome proliferator LY171883
    • P. S. Foxworthy, D. N. Perry, D. M. Hoover, and P. I. Eacho, Changes in hepatic lipid metabolism associated with lipid accumulation and its reversal in rats given peroxisome proliferator LY171883, Toxicol. Appl, Pharmacol., 106, 375-383 (1990).
    • (1990) Toxicol. Appl, Pharmacol. , vol.106 , pp. 375-383
    • Foxworthy, P.S.1    Perry, D.N.2    Hoover, D.M.3    Eacho, P.I.4
  • 35
    • 0022541973 scopus 로고
    • Toxic effects of nonadecafluoro-n-decanoic acid in rats
    • M. E. George and M. E. Andersen, Toxic effects of nonadecafluoro-n-decanoic acid in rats, Toxicol. Appl. Pharmacol., 85, 169-180 (1986).
    • (1986) Toxicol. Appl. Pharmacol. , vol.85 , pp. 169-180
    • George, M.E.1    Andersen, M.E.2
  • 36
    • 0019333103 scopus 로고
    • Acyl-CoA synthetase in rat liver peroxisomes
    • S. K. Krisans, R. M. Mortensen, and P. B. Lazarow, Acyl-CoA synthetase in rat liver peroxisomes, J. Biol. Chem., 255, 9599-9607 (1980).
    • (1980) J. Biol. Chem. , vol.255 , pp. 9599-9607
    • Krisans, S.K.1    Mortensen, R.M.2    Lazarow, P.B.3
  • 37
    • 0030273562 scopus 로고    scopus 로고
    • Potent peroxisome proliferators inhibit β-oxidation in the isolated perfused rat liver
    • in press
    • H. K. Bojes and R. G. Thurman, Potent peroxisome proliferators inhibit β-oxidation in the isolated perfused rat liver, Toxicol. Appl. Pharmacol., in press (1996).
    • (1996) Toxicol. Appl. Pharmacol.
    • Bojes, H.K.1    Thurman, R.G.2
  • 38
    • 0019158343 scopus 로고
    • Disposition of clofibrate in rat. Acute and chronic adminstration
    • J. R. Baldwin, D. T. Witiak, and D. R. Feller, Disposition of clofibrate in rat. Acute and chronic adminstration, Biochem. Pharmacol., 29, 3143-3154 (1980).
    • (1980) Biochem. Pharmacol. , vol.29 , pp. 3143-3154
    • Baldwin, J.R.1    Witiak, D.T.2    Feller, D.R.3
  • 40
    • 0025132245 scopus 로고
    • Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators
    • I. Issemann and S. Green, Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators, Nature, 347, 645-650 (1990).
    • (1990) Nature , vol.347 , pp. 645-650
    • Issemann, I.1    Green, S.2
  • 41
    • 0026551309 scopus 로고
    • Fatty acids activate a chimera of the clofibric acid-activated receptor and the glucocorticoid receptor
    • M. Gottlicher, E. Wildmark, L. Qiao, and J. Gustafsson, Fatty acids activate a chimera of the clofibric acid-activated receptor and the glucocorticoid receptor, Proc. Natl. Acad. Sci. USA, 89, 4653-4657 (1992).
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 4653-4657
    • Gottlicher, M.1    Wildmark, E.2    Qiao, L.3    Gustafsson, J.4
  • 42
    • 0022344633 scopus 로고
    • Never growth factor and epidermal growth factor induce rapid transient changes in proto-oncogene transcription in PC12 cells
    • M. E. Greenberg, L. A. Greene, and E. B. Zeff, Never growth factor and epidermal growth factor induce rapid transient changes in proto-oncogene transcription in PC12 cells, J. Biol. Chem., 260, 14101-14110 (1985).
    • (1985) J. Biol. Chem. , vol.260 , pp. 14101-14110
    • Greenberg, M.E.1    Greene, L.A.2    Zeff, E.B.3
  • 43
    • 0021213870 scopus 로고
    • Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene
    • M. E. Greenberg and E. B. Ziff, Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene, Nature, 311, 433-438 (1984).
    • (1984) Nature , vol.311 , pp. 433-438
    • Greenberg, M.E.1    Ziff, E.B.2
  • 44
    • 0025059361 scopus 로고
    • Differential down-regulation of epidermal protein kinase C by 12-O-tetradecanoylphorbol-13-acetate and diacylglycerol: Association with epidermal hyperplasia and tumor promotion
    • L. A. Hansen, N. A. Monteiro-Riviere, and R. C. Smart, Differential down-regulation of epidermal protein kinase C by 12-O-tetradecanoylphorbol-13-acetate and diacylglycerol: Association with epidermal hyperplasia and tumor promotion, Cancer Res., 50, 5740-5745 (1990).
    • (1990) Cancer Res. , vol.50 , pp. 5740-5745
    • Hansen, L.A.1    Monteiro-Riviere, N.A.2    Smart, R.C.3
  • 45
    • 0027191040 scopus 로고
    • cDNA cloning, chromosomal mapping, and functional characterization of the human peroxisome proliferator activated receptor
    • T. Sher, H. F. Yi, O. W. McBride, and F. J. Gonzalez, cDNA cloning, chromosomal mapping, and functional characterization of the human peroxisome proliferator activated receptor, Biochemistry, 32, 98-5604 (1993).
    • (1993) Biochemistry , vol.32 , pp. 98-5604
    • Sher, T.1    Yi, H.F.2    McBride, O.W.3    Gonzalez, F.J.4
  • 46
    • 0028953133 scopus 로고
    • Identification and chacracterization of DNA elements implicated in the regulation of CYP4A1 transcription
    • T. C. Aldridge, J. D. Tugwood, and S. Green, Identification and chacracterization of DNA elements implicated in the regulation of CYP4A1 transcription, Biochem. J., 306, 473-479 (1995).
    • (1995) Biochem. J. , vol.306 , pp. 473-479
    • Aldridge, T.C.1    Tugwood, J.D.2    Green, S.3
  • 47
    • 0028869502 scopus 로고
    • Expression of the peroxisome proliferator-activated receptor gene is decreased in experimental alcoholic liver disease
    • Y.-J. Y. Wan, M. Morimoto, R. G. Thurman, H. K. Bojes, and S. French, Expression of the peroxisome proliferator-activated receptor gene is decreased in experimental alcoholic liver disease, Life Sci., 56, 307-317 (1994).
    • (1994) Life Sci. , vol.56 , pp. 307-317
    • Wan, Y.-J.Y.1    Morimoto, M.2    Thurman, R.G.3    Bojes, H.K.4    French, S.5
  • 48
    • 0028997684 scopus 로고
    • Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome prolifeators
    • J
    • S. S. Lee, T. Pineau, J. Drago, E. J. Lee, J, W, Owens, D. L. Kroetz, P. M. Fernandez-Salguero et al., Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome prolifeators, Mol. Cell Biol., 15, 3012-3022 (1995).
    • (1995) Mol. Cell Biol. , vol.15 , pp. 3012-3022
    • Lee, S.S.1    Pineau, T.2    Drago, J.3    Lee, E.J.4    Owens, W.5    Kroetz, D.L.6    Fernandez-Salguero, P.M.7
  • 49
    • 0027381581 scopus 로고
    • Lack of comitogenicity by the peroxisome proliferator hepatocarcinogens, WY-14,643 and clofibric acid
    • D. S. Marsman, C. L. Swanson-Pfeiffer, and J. A. Popp, Lack of comitogenicity by the peroxisome proliferator hepatocarcinogens, WY-14,643 and clofibric acid, Toxicol. Appl. Pharmacol., 122, 1-6 (1993).
    • (1993) Toxicol. Appl. Pharmacol. , vol.122 , pp. 1-6
    • Marsman, D.S.1    Swanson-Pfeiffer, C.L.2    Popp, J.A.3
  • 50
    • 0027511845 scopus 로고
    • Tumor necrosis factor-α is a direct hepatocyte mitogen in the rat
    • H. S. Beyer and A. Theologides, Tumor necrosis factor-α is a direct hepatocyte mitogen in the rat, Bichem. Mol. Biol. Int., 29, 1-4 (1993).
    • (1993) Bichem. Mol. Biol. Int. , vol.29 , pp. 1-4
    • Beyer, H.S.1    Theologides, A.2
  • 51
    • 0020645707 scopus 로고
    • +2 flux as an initial event in phagocytosis by rat Kupffer cells
    • +2 flux as an initial event in phagocytosis by rat Kupffer cells, Eur. J. Biochem., 131, 539-543 (1983).
    • (1983) Eur. J. Biochem. , vol.131 , pp. 539-543
    • Birmelin, M.1    Decker, K.2
  • 52
    • 0343338577 scopus 로고
    • Rapid activation of protein kinase C in isolated rat liver nuclei by prolactin, a known hepatic mitogen
    • A. R. Buckley, P. D. Crowe, and D. H. Russell, Rapid activation of protein kinase C in isolated rat liver nuclei by prolactin, a known hepatic mitogen, Proc. Natl. Acad. Sci. USA, 85, 8649-8653 (1988).
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 8649-8653
    • Buckley, A.R.1    Crowe, P.D.2    Russell, D.H.3
  • 53
    • 0025122144 scopus 로고
    • Liver regeneration: Molecular mechanisms of growth control
    • G. K. Michalopoulos, Liver regeneration: Molecular mechanisms of growth control, FASEB J., 4, 176-187 (1990).
    • (1990) FASEB J. , vol.4 , pp. 176-187
    • Michalopoulos, G.K.1
  • 54
    • 0030070481 scopus 로고    scopus 로고
    • Peroxisome proliferators activate Kupffer cells in vivo
    • H. K. Bojes and R. G. Thurman, Peroxisome proliferators activate Kupffer cells in vivo, Cancer Res., 56, 1-4 (1996).
    • (1996) Cancer Res. , vol.56 , pp. 1-4
    • Bojes, H.K.1    Thurman, R.G.2
  • 55
    • 0344717800 scopus 로고    scopus 로고
    • Rapid phagocytosis of particles of the peroxisome proliferator LY171883 activates Kupffer cells
    • M. L. Rose and R. G. Thurman, Rapid phagocytosis of particles of the peroxisome proliferator LY171883 activates Kupffer cells, Fundam. Appl. Toxicol., 30, 1060 (1996).
    • (1996) Fundam. Appl. Toxicol. , vol.30 , pp. 1060
    • Rose, M.L.1    Thurman, R.G.2
  • 56
    • 0025051058 scopus 로고
    • Biologically active products of stimulated liver macrophages (Kupffer cells)
    • K. Decker, Biologically active products of stimulated liver macrophages (Kupffer cells), Eur. J. Biochem., 192, 245-261 (1990).
    • (1990) Eur. J. Biochem. , vol.192 , pp. 245-261
    • Decker, K.1
  • 58
    • 0028235639 scopus 로고
    • Cholesteryl esters from oxidized low-density lipoproteins are in vivo rapidly hydrolyzed in rat Kupffer cells and transported to liver parenchymal cells and bile
    • M. N. Pieters, S. Esbach, D. Schouten, A. Brower, D. L. Knook, and T. J. von Berkel, Cholesteryl esters from oxidized low-density lipoproteins are in vivo rapidly hydrolyzed in rat Kupffer cells and transported to liver parenchymal cells and bile, Hepatology, 19, 1459-1467 (1994).
    • (1994) Hepatology , vol.19 , pp. 1459-1467
    • Pieters, M.N.1    Esbach, S.2    Schouten, D.3    Brower, A.4    Knook, D.L.5    Von Berkel, T.J.6
  • 59
    • 0028208243 scopus 로고
    • Suppression of liver cell apoptosis in vitro by the nongenotoxic hepatocarcinogen and peroxisome proliferator nafenopin
    • A. C. Bayly, R. A. Roberts, and C. Dive, Suppression of liver cell apoptosis in vitro by the nongenotoxic hepatocarcinogen and peroxisome proliferator nafenopin, J. Cell Biol., 125, 197-203 (1994).
    • (1994) J. Cell Biol. , vol.125 , pp. 197-203
    • Bayly, A.C.1    Roberts, R.A.2    Dive, C.3
  • 60
    • 0005432046 scopus 로고
    • Biochemistry of Arachidonic Acid Metabolism
    • W. E. M. Lands, ed., Matinus Nijhoff, Boston
    • L. W. Daniel, in Phopholipases (W. E. M. Lands, ed.), Biochemistry of Arachidonic Acid Metabolism, Matinus Nijhoff, Boston, 1985, pp. 175-193.
    • (1985) Phopholipases , pp. 175-193
    • Daniel, L.W.1
  • 61
    • 0028362173 scopus 로고
    • Increase in oxygen uptake due to arachidonic acid is oxygen dependent in the perfused liver
    • Y. Nakagawa, T. Matsumura, M. Goto, W. Qu, F. C. Kauffman, and R. G. Thurman, Increase in oxygen uptake due to arachidonic acid is oxygen dependent in the perfused liver, Am. J. Physiol., 266, G953-G959 (1994).
    • (1994) Am. J. Physiol. , vol.266
    • Nakagawa, Y.1    Matsumura, T.2    Goto, M.3    Qu, W.4    Kauffman, F.C.5    Thurman, R.G.6
  • 62
    • 15844417025 scopus 로고    scopus 로고
    • 2 consumption: Effect of alcohol treatment on cell-cell communication
    • 2 consumption: Effect of alcohol treatment on cell-cell communication, Am. J. Physiol., 270, G575-G580 (1996).
    • (1996) Am. J. Physiol. , vol.270
    • Qu, W.1    Zhong, Z.2    Goto, M.3    Thurman, R.G.4
  • 63
    • 0023954297 scopus 로고
    • Cahectin (tumor necrosis factor): A macrophage hormone governing cellular metabolism and inflammatory response
    • B. Beutler and A. Cerami, Cahectin (tumor necrosis factor): A macrophage hormone governing cellular metabolism and inflammatory response, Endocrine Rev., 9, 57-66 (1988).
    • (1988) Endocrine Rev. , vol.9 , pp. 57-66
    • Beutler, B.1    Cerami, A.2
  • 64
    • 0026801421 scopus 로고
    • Antibodies to tumor necrosis factor-α inhibit liver regeneration after partial hepatectomy
    • P. Akerman, P. Cote, S. Q. Yang, C. McClain, S. Nelson, G. J. Bagby, A. M. Diehl et al., Antibodies to tumor necrosis factor-α inhibit liver regeneration after partial hepatectomy, Am. J. Physiol., 263, G579-G585 (1992).
    • (1992) Am. J. Physiol. , vol.263
    • Akerman, P.1    Cote, P.2    Yang, S.Q.3    McClain, C.4    Nelson, S.5    Bagby, G.J.6    Diehl, A.M.7
  • 65
    • 0031417341 scopus 로고    scopus 로고
    • Antibodies to tumor necrosis factor α prevent increases in cell replication in liver due to the potent peroxisome proliferator, WY-14,643
    • in press
    • H. K. Bojes, D. R. Gemolec, P. Simeonova, A. Bruccoleri, R. Schoonhoven, M. I. Luster, and R. G. Thurman, Antibodies to tumor necrosis factor α prevent increases in cell replication in liver due to the potent peroxisome proliferator, WY-14,643, Carcinogenesis (1997) (in press).
    • (1997) Carcinogenesis
    • Bojes, H.K.1    Gemolec, D.R.2    Simeonova, P.3    Bruccoleri, A.4    Schoonhoven, R.5    Luster, M.I.6    Thurman, R.G.7
  • 66
    • 0025194735 scopus 로고
    • Depresses liver regeneration after partial hepatectomy of germ-free, athymic and lipopolysaccharide-resistant mice
    • R. P. Cornell, B. L. Lijequist, and K. F. Bartizal, Depresses liver regeneration after partial hepatectomy of germ-free, athymic and lipopolysaccharide-resistant mice, Hepatology, 11, 916-922 (1990).
    • (1990) Hepatology , vol.11 , pp. 916-922
    • Cornell, R.P.1    Lijequist, B.L.2    Bartizal, K.F.3
  • 67
    • 0021964534 scopus 로고
    • Induction of ornithine decarboxylase in liver and spleen of mice by interleuken 1-like factors produced from a macrophage line
    • Y. Endo, R. Suzuki, and K. Kumagi, Induction of ornithine decarboxylase in liver and spleen of mice by interleuken 1-like factors produced from a macrophage line, Biochem. Biophys. Acta, 838, 343-350 (1985).
    • (1985) Biochem. Biophys. Acta , vol.838 , pp. 343-350
    • Endo, Y.1    Suzuki, R.2    Kumagi, K.3
  • 68
    • 0025918191 scopus 로고
    • Apoptosis in cultured rat hepatocytes: The effects of tumor necrosis factor α and interferon γ
    • T. Shinagawa, K. Yoshioka, S. Kakumu, T. Wakita, T. Ishikawa, Y. Itoh, and M. Takayanagi, Apoptosis in cultured rat hepatocytes: The effects of tumor necrosis factor α and interferon γ, J. Pathol., 165, 247-253 (1991).
    • (1991) J. Pathol. , vol.165 , pp. 247-253
    • Shinagawa, T.1    Yoshioka, K.2    Kakumu, S.3    Wakita, T.4    Ishikawa, T.5    Itoh, Y.6    Takayanagi, M.7
  • 70
    • 0027994349 scopus 로고
    • The spingomyelin cycle and the second messenger function of ceramide
    • Y. A. Hannun, The spingomyelin cycle and the second messenger function of ceramide, J. Biol. Chem., 269, 3125-3128 (1994).
    • (1994) J. Biol. Chem. , vol.269 , pp. 3125-3128
    • Hannun, Y.A.1
  • 71
    • 0028333052 scopus 로고
    • Tumor necrosis facator receptor-mediated signaling pathways
    • R. A. Heller and M. Kronke, Tumor necrosis facator receptor-mediated signaling pathways, J. Cell. Biol., 126, 5-9 (1994).
    • (1994) J. Cell. Biol. , vol.126 , pp. 5-9
    • Heller, R.A.1    Kronke, M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.