Modulation of B12 Dosage and Response in Fetal Treatment of Methylmalonic Aciduria (MMA): Titration of Treatment Dose to Serum and Urine MMA

Fetal Diagnosis and Therapy

Volumn 12, Issue 1, 1997, Pages 21-23

  Evans, Mark I ^a,b,c   Duquette, Debra A ^a,b   Rinaldo, Piero ^e   Bawle, Erawati ^d   Rosenblatt, David S ^f   Whitty, Janice ^a   Quintero, Ruben A ^a   Johnson, Mark P ^a,b,c  

^a Departments of Obstetrics and Gynecology   (United States)

^b Center for Molecular Medicine and Genetics   (United States)

^c Veterans Affairs   (United States)

^d WAYNE STATE UNIVERSITY   (United States)

^e MCGILL UNIVERSITY   (Canada)

^f YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Fetal therapy; Methylmalonic aciduria; Prenatal diagnosis

Indexed keywords

CYANOCOBALAMIN; METHYLMALONIC ACID; 5 METHYLTETRAHYDROFOLIC ACID; COBAMAMIDE; COENZYME A; PROPIONIC ACID;

ADULT; AMNIOCENTESIS; ARTICLE; BLOOD; CASE REPORT; DISORDERS OF AMINO ACID AND PROTEIN METABOLISM; FEMALE; FETUS DISEASE; GESTATIONAL AGE; HUMAN; PREGNANCY; URINE; AMNION CELL; AMNION FLUID; BLOOD LEVEL; COMA; DEHYDRATION; DEVELOPMENTAL DISORDER; DOSE RESPONSE; FAILURE TO THRIVE; FETUS; KARYOTYPE; MALE; MATERNAL BLOOD; METHYLMALONIC ACIDURIA; PLACENTA; PRENATAL DIAGNOSIS; PRIORITY JOURNAL; TITRIMETRY; URINE LEVEL;

ADULT; AMINO ACID METABOLISM, INBORN ERRORS; AMNIOCENTESIS; FEMALE; FETAL DISEASES; GESTATIONAL AGE; HUMANS; METHYLMALONIC ACID; PREGNANCY; VITAMIN B 12;

EID: 0030610123     PISSN: 10153837     EISSN: 14219964     Source Type: Journal    
DOI: 10.1159/000264418     Document Type: Article

References (7)

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7. Rosenblatt DS, Cooper BA, Schmutz SM, et al: Prenatal vitamin Bn therapy of a fetus with methylmalonic deficiency. Lancet 1985;1: 1127.