Sequence of mouse 17β-hydroxysteroid dehydrogenase type 3 cDNA and tissue distribution of the type 1 and type 3 isoform mRNAs

Journal of Steroid Biochemistry and Molecular Biology

Volumn 60, Issue 1-2, 1997, Pages 19-24

  Sha, J A ^a   Dudley, K ^b   Rajapaksha, W R A K J S ^a   O'Shaughnessy, P J ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; ISOENZYME; MESSENGER RNA; TESTOSTERONE 17BETA DEHYDROGENASE; 3(17) HYDROXYSTEROID DEHYDROGENASE; 3(17)-HYDROXYSTEROID DEHYDROGENASE; HYDROXYSTEROID DEHYDROGENASE;

AMINO ACID SEQUENCE; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ANALYSIS; FEMALE; HISTOCHEMISTRY; HUMAN; MALE; NONHUMAN; OVARY; POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY; SPECIES DIFFERENCE; TESTIS; TISSUE DISTRIBUTION; ANIMAL; DNA SEQUENCE; GENETICS; METABOLISM; METHODOLOGY; MOLECULAR GENETICS; MOUSE; NUCLEOTIDE SEQUENCE; PROTEIN SYNTHESIS; SPLEEN;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; FEMALE; HUMANS; HYDROXYSTEROID DEHYDROGENASES; ISOENZYMES; MALE; MICE; MOLECULAR SEQUENCE DATA; OVARY; POLYMERASE CHAIN REACTION; PROTEIN BIOSYNTHESIS; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY, AMINO ACID; SPLEEN; TESTIS; TISSUE DISTRIBUTION;

EID: 0030609848     PISSN: 09600760     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-0760(96)00165-3     Document Type: Article

References (16)

1. Martel C., Rheaume E., Takahashi M., Trudel C., Couet J., Luuthe V., Simard J. and Labrie F.: Distribution of 17β-hydroxysteroid dehydrogenase gene-expression and activity in rat and human tissues. J. Steroid Biochem. Molec. Biol 41 (1992) 597-603.
2. Ryan K. J. and Engel L.: The interconversion of estrone and estradiol by human tissue slices. Endocrinology 52 (1953) 287-291.
3. Peltoketo H., Isomma V., Maentausta O. and Vihko R.: Complete amino acid sequence of human placental 17β-hydroxysteroid dehydrogenase deduced from cDNA. FEBS Lett. 239 (1988) 73-77.
4. Wu L., Einstein M., Geissler W. M., Chan H. K., Elliston K. O. and Andersson S.: Expression cloning and characterization of human 17β-hydroxysteroid dehydrogenase type 2, a microsomal-enzyme possessing 20α-hydroxysteroid dehydrogenase activity. J. Biol. Chem. 268 (1993) 12964-12969.
5. Geissler W. M., Davis D. L., Wu L., Bradshaw K. D., Patel S., Mendonca B. B., Elliston K. O., Wilson J. D., Russell D. W. and Andersson S.: Male pseudohermaphroditism caused by mutations of testicular 17β-hydroxysteroid dehydrogenase-3. Nature Genet. 7 (1994) 34-39.
6. Adamski J., Normand T., Leenders F., Monte D., Begue A., Stehelin D., Jungblut P. W. and Delaunoit Y.: Molecular cloning of a novel widely expressed human 80 kDa 17β-hydroxy-steroid dehydrogenase-IV. Biochem. J. 311 (1995) 437-443.
7. Zhang Y., Dufort I., Soucy P., Labrie F. and Luu-The V.: Cloning and expression of human type V 17β-hydroxysteroid dehydrogenase. Endocr. Soc. (1995) Abstract P3-614.
8. Luu-The V., Labrie C., Simard J., Lachance Y., Zhao H.-F., Couet J., Leblanc G. and Labrie F.: Structure of two in tandem human 17β-hydroxysteroid dehydrogenase genes. Molec. Endocr. 4 (1990) 268-275.
9. Ghersevich S., Nokelainen P., Poutanen M., Orava M., Autio-Harmainen H., Rajaniemi H. and Vihko R.: Rat 17β-hydroxysteroid dehydrogenase type1: primary structure and regulation of enzyme expression in rat ovary by diethylstilbestrol and gonadotrpins in vitro. Endocrinology 135 (1994) 1477-1487.
10. Frohman M. A., Dush M. K. and Martin G. R.: Rapid production of full-length cDNAs from rare transcripts: amplification using a single gene-specific oligonucleotide primer. Proc. Natl. Acad. Sci. U.S.A. 85 (1988) 8998-9002.
11. Gubler U. and Hoffman B. J.: A simple and very efficient method for generating complimentary DNA libraries. Gene 25 (1983) 263-269.
12. Higuchi R. G. and Ochman H.: Production of single stranded DNA templates by exonuclease. Nucl. Acids Res. 17 (1989) 5865.
13. O'Shaughnessy P. J. and Murphy L.: Cytochrome P450 17α-hydroxylase protein and mRNA in the testis of the testicular feminized (Tfm) mouse. J. Molec. Endocr. 11 (1993) 77-82.
14. Sha J., Baker P. and O'Shaughnessy P. J.: Both reductive forms of 17β-hydroxysteroid dehydrogenase (types 1 and 3) are expressed during development in the mouse testis. Biochem. Biophys. Res. Commun. 222 (1996) 90-94.
15. Kyte J. and Doolittle R. F.: A simple method for displaying the hydropathic character of a protein. J. Molec. Biol. 157 (1982) 105-132.
16. Poutanen M., Miettinen M. and Vihko R.: Differential estrogen substrate specificities for transiently expressed human placental 17β-hydroxysteroid. Endocrinology 133 (1993) 2639-2644.