Influence of interleukin 1α on superoxide anion, platelet activating factor release and phospholipase A2 activity of naive and sensitized guinea-pig alveolar macrophages

British Journal of Pharmacology

Volumn 122, Issue 7, 1997, Pages 1345-1352

  Mugnai, Sabrina ^a   Ciuffi, Mario ^a   Maurizi, Manuela ^a   Bindi, Daniela ^a   Franchi Micheli, Sergio ^a   Zilletti, Lucilla ^a  

^a Dept Preclin Clin Pharmacol M ^*  (Italy)

Author keywords

Alveolar macrophages; Cytokines; Cytosolic phospholipase A2 activity; Platelet activating factor; Sensitization; Superoxide anion

Indexed keywords

4 BROMOPHENACYL BROMIDE; ARACHIDONYL TRIFLUOROMETHYL KETONE; CYTOCHROME C; FORMYLMETHIONYLLEUCYLPHENYLALANINE; INTERLEUKIN 1ALPHA; KETONE DERIVATIVE; METHYLPREDNISOLONE; PHOSPHOLIPASE A2; PROSTAGLANDIN E2; SUPEROXIDE; THROMBOCYTE ACTIVATING FACTOR; UNCLASSIFIED DRUG; CYTOKINE; INTERLEUKIN 1; OXYGEN; PHOSPHOLIPASE A;

ARTICLE; CELL STIMULATION; CONTROLLED STUDY; ENZYME ACTIVITY; GUINEA PIG; HUMAN CELL; HYDROLYSIS; LUNG ALVEOLUS MACROPHAGE; MALE; NONHUMAN; PRIORITY JOURNAL; PROSTAGLANDIN RELEASE; RADIOIMMUNOASSAY; SENSITIZATION; THROMBOCYTE AGGREGATION; ANIMAL; DRUG ANTAGONISM; DRUG EFFECT; METABOLISM;

ANIMALS; CYTOKINES; DINOPROSTONE; GUINEA PIGS; INTERLEUKIN-1; MACROPHAGES, ALVEOLAR; N-FORMYLMETHIONINE LEUCYL-PHENYLALANINE; OXYGEN; PHOSPHOLIPASES A; PLATELET ACTIVATING FACTOR; SUPEROXIDES;

EID: 0030609173     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0701521     Document Type: Article

References (51)

1. ADAMS, D.O. & HAMILTON, T.A. (1992). Macrophages as destructive cells in host defence. In Inflammation: Basic Principles and Clinical Correlates. ed. Gallin J.I., Goldstein I.M. & Snyderman R. pp. 637-662. New York: Raven Press Ltd.
2. 2 and cyclooxygenase-2. Eur. J. Biochem., 125-131.
3. BAZAN, N.G. (1995). A signal terminator. Nature, 374, 501-502.
4. BEUSENBERG, F.D., LEURS, R., VAN SCHAIK, A., VAN AMSTERDAM, J.G.C. & BONTA, I.L. (1991). Sensitisation enhances the adenylyl cyclase responsiveness in alveolar macrophages. Biochem. Pharmacol., 42, 485-490.
5. 2-activating protein, and release of linoleic acid from the murine T-helper cell line EL-4. J. Immunol., 148, 155-160.
6. BROMBERG, Y. & PICK, E. (1983). Unsaturated fatty acids as second messengers of superoxide generation by macrophages. Cell Immunol., 79, 240-252.
7. BRUNELLESCHI, S., PARENTI, A., CENI, E., GIOTTI, A. & FANTOZZI, R. (1992). Enhanced responsiveness of ovalbumin-sensitised guinea-pig alveolar macrophages to tachykinins. Br. J. Pharmacol., 107, 964-969.
8. BUSSOLINO, F., ARESE, M., SILVESTRO, L., SOLDI, R., BENFENATI, E., SANAVIO, F., AGLIETTA, M., BOSIA, A. & CAMUSSI, G. (1994). Involvement of a serine protease in the synthesis of platelet-activating factor by endothelial cells stimulated by tumor necrosis factor α or interleukin 1α. Eur. J. Immunol., 24, 3131-3139.
9. 2 formation in rat corticocerebral tissue in vitro. Biochem. Pharmacol., 52, 97-103.
10. 2+-dependent translocation domain with homology to PKC and GAP. Cell, 65, 1043-1051.
11. DALE, M.M. (1965). The applicability of anaphylactic tests in studies of antigen mixtures. Immunology, 8, 435-443.
12. DENNIS, E.A., ACKERMANN, E.J., DENNIS, R.A., DEEMS, R.A. & REYNOLDS, L.J. (1995). Multiple forms of phospholipase A2 in macrophages capable of arachidonic acid release for eicosanoid biosynthesis. Adv. Prostaglandin Thromboxane Leukotriene Res., 23, 75-80.
13. DINARELLO, C.A. (1991). Interleukin-1 and interleukin-1 antagonism. Blood, 77, 1627-1652.
14. 2. Br. J. Pharmacol., 88, 463-472.
15. DULARAY, B., ELSON, C.J., CLEMENTS-JEWERY, S., DAMAIS, C. & LANDO, D. (1990). Recombinant human interleukin-1β primes human polymorphonuclear leukocytes for stimulus-induced myeloperoxidase release. J. Leukoc. Biol., 41, 158-163.
16. 2 translocates to membrane fraction in human neutrophils activated by stimuli that phosphorylate mitogen-activated protein kinase. Biochemistry, 91, 3142-3146.
17. ELIAKIM, R., KARMELI, F., RAZIN, E. & RACHMILEWITZ, D. (1988). Role of platelet-activating factor in ulcerative colitis. Gastroenterology, 95, 1167-1172.
18. FITZGERALD, M.F., PARENTE, L. & WHITTLE, B.J.R. (1989). Release of PAF-acether and eicosanoids from guinea pig alveolar macrophages by fMLP: effect of cyclo-oxygenase and lipoxygenase inhibition. Eur. J. Pharmacol., 164, 539-546.
19. FULLER, R. W. (1992). Macrophages. In Asthma. Basic Mechanisms and Clinical Management. ed. Barnes, P.I., Rodger, I.W. & Thomson, N.C. pp. 99-109. New York: Academic Press.
20. GEORGILIS, K., SCHAEFER, C., DINARELLO, C.A. & KLEMPNER, M.S. (1987). Human recombinant interleukin 1β has no effect on intracellular calcium or on functional responses of human neutrophils. J. Immunol., 138, 3403-3407.
21. 2 enzymes: regulation and inhibition. Trends Pharmacol. Sci., 14, 92-98.
22. 2 by phosphorylation in rat mesangial cells. J. Clin. Invest., 93, 1224-1233.
23. HARRIS, C.A., DERBIN, K.S., HUNTE-MCDONOUGH, B., KRAUSS, M.R., CHEN, K.T., SMITH, D.M. & EPSTEIN, L.B. (1991). Manganese superoxide dismutase is induced by IFN-γ in multiple cell types. J. Immunol., 147, 149-154.
24. 2 inhibitors. Biochem. J., 264, 249-255.
25. 2 by guinea pig alveolar macrophages. J. Immunol., 151, 5613-5623.
26. 2 in rheumatoid synovial fibroblasts. Biochem. Biophys. Res. Commun., 184, 712-718.
27. KADIRI, C., CHERQUI, G., MASLIAH, J., RYBKINE, T., ETIENNE, J. & BÉRÉZIAT, G. (1990). Mechanism of N-formyl-methionyl-leucyl-phenylalanine- and platelet-activating factor-induced arachidonic acid release in guinea pig alveolar macrophages: involvement of a GTP-binding protein and role of protein kinase A and protein kinase C. Mol. Pharmacol., 38, 418-425.
28. 2. Agents Actions, 46, 65-76.
29. LANDS, W., KULMAER, R.S. & MARSHALL, P.J. (1984). Lipid peroxide actions in the regulation of prostaglandin biosynthesis. In Free Radicals in Biology. ed. Pregor, W.A. pp. 39-61. New York: Academic Press.
30. 2 in human fibroblasts. J. Biol. Chem., 267, 23451-23454.
31. LOWRY, O.H., ROSEBROUGH, N.J., FARR, A.L. & RANDALL, R.J. (1951). Protein measurement with Folin phenol reagent. J. Biol. Chem., 193, 265-275.
32. MASSEY, V. (1959). The microextimation of succinate and the extinction coefficient of cytochrome c. Biochem. Biophys. Acta, 34, 255-256.
33. 2(s); comparison of arachidonoyl-selective and nonselective enzymes. FASEB J., 7, 339-348.
34. M'RINI, C., PIPY, B., RAMI, J. & BESOMBES, J. (1994). Arachidonic acid metabolism in alveolar macrophages from actively sensitized guinea-pigs: effects of sensitization and specific allergen. Biochim. Biophys. Acta, 1213, 46-56.
35. 2 enzymes: regulation and physiological role. Biochem. Pharmacol., 48, 1-10.
36. MYRVIK, Q.N., LEAKE, E.S. & FARIS, B. (1961). Studies on pulmonary alveolar macrophages from the normal rabbit: a technique to procure them in a state of purity. J. Immunol., 86, 128-132.
37. POULTER, L.W., JANOSSY, G., POWER, C., SREENAN, S. & BURKE, C. (1994). Immunological/physiological relationships in asthma: potential regulation by lung macrophages. Immunol. Today, 15, 258-261.
38. RANKIN, J.A. (1989). The contribution of alveolar macrophages to hyperreactive airway disease. J. Allergy Clin. Immunol., 83, 722-729.
39. 2, blocks production of arachidonate and 12-hydroxyeicosatetraenoic acid by calcium ionophore-challenged platelets. J. Biol. Chem., 22, 15619-15624.
40. γ receptor-mediated superoxide generation in macrophages. J. Immunol., 138, 4353-4359.
41. SAMPLE, A.K. & CZUPRYNSKI, C.J. (1991). Priming and stimulation of bovine neutrophils by recombinant human interleukin-1 alpha and tumor necrosis factor alpha. J. Leukoc. Biol., 49, 107-115.
42. SANE, A.C., MENDENHALL, T. & BASS, D. (1996). Secretory phospholipase A2 activity is elevated in bronchoalveolar lavage fluid after ovalbumin sensitisation of guinea pigs. J. Leukoc. Biol., 60, 704-709.
43. 2 activity and protein synthesis is blocked by dexamethasone in rat mesangial cells. FEBS Letts, 333, 339-343.
44. SCHÜTZE, S., MACHLEIDT, T. & KRÖNKE, M. (1994). The role of diacylglycerol and ceramide in tumor necrosis factor and interleukin-1 signal transduction. J. Leukoc. Biol., 56, 533-541.
45. SMITH, H. (1989). Animal models of asthma. Pulmonary Pharmacol., 2, 59-74.
46. SMOLEN, J.E. & WEISSMANN, O. (1980). Effect of indomethacin, 5,8,11,14-eicosatetraynoic acid, and p-bromophenacylbromide on lysosomal enzyme release and superoxide anion generation by human polymorphonuclear leukocytes. Biochem. Pharmacol., 29, 533-538.
47. SNYDER, F. (1995). Platelet-activating factor and its analogs: metabolic pathways and related intracellular processes. Biochim. Biophys. Acta, 1254, 231-249.
48. 2. Biochemistry, 32, 5935-5940.
49. TAO, W., DOUGHERTY, R., JOHNSON, P. & PICKETT, W. (1993). Recombinant bovine GM-CSF primes superoxide production but not degranulation induced by recombinant bovine interleukin-1β in bovine neutrophils. J. Leukoc. Biol., 53, 679-684.
50. 2. J. Clin. Invest., 93, 571-577.
51. ZIMMERMAN, G.A., PRESCOTT, S.M. & MCINTYRE, T.M. (1992). Platelet-activating factor. A fluid-phase and cell-associated mediator of inflammation. In Inflammation: Basic Principles and Clinical Correlates. ed. Gallin, J.I., Goldstein, I.M. & Snyderman, R. New York: Raven Press Ltd.