Molecular linkage of the human α1-antitrypsin and corticosteroid-binding globulin genes on chromosome 14q32.1

Mammalian Genome

Volumn 8, Issue 12, 1997, Pages 913-916

  Rollini, Pierre ^a   Fournier, R E K ^a  

^a Fred Hutchinson Cancer Research Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 1 ANTITRYPSIN; SERINE PROTEINASE INHIBITOR; TRANSCORTIN;

ARTICLE; CHROMOSOME 14; CHROMOSOME MAP; GENETICS; HUMAN; NUCLEOTIDE REPEAT; RESTRICTION FRAGMENT LENGTH POLYMORPHISM;

ALPHA 1-ANTITRYPSIN; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 14; HUMANS; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; REPETITIVE SEQUENCES, NUCLEIC ACID; SERPINS; TRANSCORTIN;

EID: 0030609166     PISSN: 09388990     EISSN: None     Source Type: Journal    
DOI: 10.1007/s003359900610     Document Type: Article

References (24)

1. Abbott CM, McMahon CJ, Kelsey GD, Parkar M, Whitehouse DB, Corney G, Povey S, Hopkinson DA, Mieli-Vergani G, Mowat A (1987) α-1 Antitrypsin-related gene (ATR) for prenatal diagnosis. Lancet I, 1425-1426
2. Bao J, Reed-Fourquet L, Sifers RN, Kidd VJ, Woo SLC (1988) Molecular structure and sequence homology of a gene related to α-1 antitrypsin in the human genome. Genomics 2, 165-173
3. Billingsley GD, Walter MA, Hammond GL, Cox DW (1993) Physical mapping of four serpin genes: α-1 antitrypsin, α-1 antichymotrypsin, corticosteroid-binding globulin, and protein C inhibitor, within a 280-kb region on chromosome 14q32.1. Am J Hum Genet 52, 343-353
4. Byth BC, Billingsley GD, Cox DW (1994) Physical and genetic mapping of the serpin gene cluster at 14q32.1: allelic association and a unique haplotype associated with α-1 antitrypsin deficiency. Am J Hum Genet 55, 126-133
5. Chai KX, Chen L-M, Chao J, Chao L (1993) Kallistatin: a novel human serine proteinase inhibitor. J Biol Chem 268, 24498-24505
6. Chai KX, Ward DC, Chao J, Chao L (1994) Molecular cloning, sequence analysis, and chromosomal localization of the human protease inhibitor 4 (kallistatin) gene (PI4). Genomics 23, 370-378
7. Cox DW, Woo SLC, Mansfield T (1985) DNA restriction fragments associated with α-1 antitrypsin indicate a single origin for deficiency allele PI Z. Nature 316, 79-81
8. Cox DW, Billingsley GD (1986) Restriction enzyme MaeIII for prenatal diagnosis of α-1 antitrypsin deficiency. Lancet 2, 741-742
9. Hafeez W, Ciliberto G, Perlmutter DH (1992) Constitutive and modulated expression of the human α-1 antitrypsin gene. J Clin Invest 89, 1214-1222
10. Herrmann R, Han T, Barcos MP, Lok MS, Henderson ES (1980) Malignant lymphoma of pre-T cell type terminating in acute myelocytic leukemia. A case report with enzymic and immunologic marker studies. Cancer 46, 1383-1388
11. Hofker MH, Nelen M, Klasen EC, Nukiwa T, Curiel D, Crystal RG, Frants RR (1988) Cloning and characterization of an a-1 antitrypsin like gene 12 kb downstream of the genuine α-1 antitrypsin gene. Biochem Biophys Res Commun 155, 634-642
12. Kelsey GD, Povey S, Bygrave AE, Lovell-Badge RH (1987) Species- and tissue-specific expression of human α-1 antitrypsin in transgenic mice. Genes Dev 1, 161-171
13. Kelsey GD, Parkar M, Povey S (1988) The human alpha-1-antitrypsin-related sequence: isolation and investigation of its expression. Ann Hum Genet 52, 151-160
14. Knowles BB, Howe CC, Aden DP (1980) Human hepatocellular carcinoma cell lines secrete the major plasma proteins and hepatitis B surface antigen. Science 209, 497-499
15. Long GL, Chandra T, Woo SLC, Davie EW, Kurachi K (1984) Complete sequence of the cDNA for human α-1 antitrypsin and the gene for the S variant. Biochemistry 23, 4828-4837
16. Meijers JCM, Chung DW (1991) Organization of the gene coding for human protein C inhibitor (plasminogen activator inhibitor-3). J Biol Chem 266, 15028-15034
17. Potempa J, Korzus E, Travis J (1994) The serpin superfamily of proteinase inhibitors: structure, function, and regulation. J Biol Chem 269, 15957-15960
18. Pulciani S, Santos E, Lauver AV, Long LK, Aaronson SA, Barbacid M (1982) Oncogenes in solid human tumors. Nature 300, 539-542
19. Purrello M, Alhadeff B, Whittington E, Buckton KE, Daniel A, Arnaud P, Rocchi M, Archidiacono N, Filippi G, Siniscalco M (1987) Comparison of cytologic and genetic distances between long arm subtelomeric markers of human autosome 14 suggests uneven distribution of crossing-over. Cytogenet Cell Genet 44, 32-40
20. Rabin M, Watson M, Kidd V, Woo SLC, Breg RW, Ruddle F (1986) Regional location of α-1 antichymotrypsin and α-1 antitrypsin genes on human chromosome 14. Somatic Cell Mol Genet 12, 209-214
21. Sambrook J, Fritsch EF, Maniatis T (1989) Molecular Cloning: A Laboratory Manual, 2nd ed. (Cold Spring Harbor, N.Y.: Cold Spring Harbor Laboratory Press)
22. Sefton L, Kelsey G, Kearney P, Povey S, Wolfe J (1990) A physical map of the human PI and AACT genes. Genomics 7, 382-388
23. Seralini GE, Beruhe D, Gagne R, Hammond GL (1990) The human corticosteroid binding globulin gene is located on chromosome 14q31q32.1 near two other serine protease inhibitor genes. Hum Genet 86, 73-75
24. Underhill DA, Hammond GL (1989) Organization of the human corticosteroid binding globulin gene and analysis of its 5′-flanking region. Mol Endocrinol 3, 1448-1454