-
2
-
-
0343297441
-
A new method for the production of electrophilic F-18 starting from aqueous [F-18] fiuoride
-
Bergman, J., Källman, K.-M., Solin, O., DeJesus, O.T., Oakes, T.R., and Nickles, R.J. (1993) A new method for the production of electrophilic F-18 starting from aqueous [F-18] fiuoride. J. Nucl. Med. Abstr., 34:69P.
-
(1993)
J. Nucl. Med. Abstr.
, vol.34
-
-
Bergman, J.1
Källman, K.-M.2
Solin, O.3
DeJesus, O.T.4
Oakes, T.R.5
Nickles, R.J.6
-
4
-
-
0018159794
-
Long term treatment with L-deprenyl
-
Birkmayer, W. (1978) Long term treatment with L-deprenyl. J. Neural. Transm., 43:239-244.
-
(1978)
J. Neural. Transm.
, vol.43
, pp. 239-244
-
-
Birkmayer, W.1
-
7
-
-
0000224448
-
Unified Parkinson's Disease Rating Scale
-
S. Fahn, C.D. Marsden, M. Goldstein, and D.B. Calne, eds. Macmillan Healthcare Information, Florham Park, NJ
-
Fahn, S., Elton, R.L., and members of the UPDRS Development Committee (1987) Unified Parkinson's Disease Rating Scale. In: Recent Developments in Parkinson's Disease, Vol. 2. S. Fahn, C.D. Marsden, M. Goldstein, and D.B. Calne, eds. Macmillan Healthcare Information, Florham Park, NJ, pp. 153-163.
-
(1987)
Recent Developments in Parkinson's Disease
, vol.2
, pp. 153-163
-
-
Fahn, S.1
Elton, R.L.2
-
8
-
-
0019720570
-
L-dopa (L-3,4-dihydroxyphenylalanine) uptake by human red blood cells
-
Floud, A., and Fahn, S. (1981) L-dopa (L-3,4-dihydroxyphenylalanine) uptake by human red blood cells. Biochim. Biophys. Acta, 645:165-169.
-
(1981)
Biochim. Biophys. Acta
, vol.645
, pp. 165-169
-
-
Floud, A.1
Fahn, S.2
-
9
-
-
0017912168
-
18F]fluoro-dopa, an analogue of dopa, and its use in direct external measurements of storage, degradation, and turnover of intracerebral dopamine
-
18F]fluoro-dopa, an analogue of dopa, and its use in direct external measurements of storage, degradation, and turnover of intracerebral dopamine. Proc. Natl. Acad. Sci. U. S. A., 75:464-467.
-
(1978)
Proc. Natl. Acad. Sci. U. S. A.
, vol.75
, pp. 464-467
-
-
Garnett, E.S.1
Firnau, G.2
Chan, P.K.H.3
Sood, S.4
Belbeck, L.W.5
-
10
-
-
0020321344
-
Calculation of cerebral glucose phosphorylation from brain uptake of glucose analogs in vivo: A re-examination
-
Gjedde, A. (1982) Calculation of cerebral glucose phosphorylation from brain uptake of glucose analogs in vivo: A re-examination. Brain Res. Rev., 4:237-274.
-
(1982)
Brain Res. Rev.
, vol.4
, pp. 237-274
-
-
Gjedde, A.1
-
11
-
-
0025767662
-
Dopa decarboxylase activity of the living human brain
-
Gjedde, A., Reith, J., Dyve, S., Léger, G., Guttman, M., Diksic, M., Evans, A., and Kuwabara, H. (1991) Dopa decarboxylase activity of the living human brain. Proc. Natl. Acad. Sci. U. S. A., 88:2721-2725.
-
(1991)
Proc. Natl. Acad. Sci. U. S. A.
, vol.88
, pp. 2721-2725
-
-
Gjedde, A.1
Reith, J.2
Dyve, S.3
Léger, G.4
Guttman, M.5
Diksic, M.6
Evans, A.7
Kuwabara, H.8
-
12
-
-
0028862753
-
18F]fluoro-L-dopa in rhesus monkey
-
18F]fluoro-L-dopa in rhesus monkey. Nucl. Med, Biol., 22:921-927.
-
(1995)
Nucl. Med, Biol.
, vol.22
, pp. 921-927
-
-
Günther, I.1
Psylla, M.2
Reddy, G.N.3
Antonini, A.4
Vontobel, P.5
Reist, H.W.6
Zollinger, A.7
Nickles, R.J.8
Beer, H.-F.9
Schubiger, P.A.10
Leenders, K.L.11
-
13
-
-
0026724717
-
3-O-methyldopa administration does not alter fluorodopa transport into the brain
-
Guttman, M., Léger, G., Cedarbaum, J.M., Reches, A., Woodward, W., Evans, A., Diksic, M., and Gjedde, A. (1992) 3-O-methyldopa administration does not alter fluorodopa transport into the brain. Ann. Neurol., 31:638-643.
-
(1992)
Ann. Neurol.
, vol.31
, pp. 638-643
-
-
Guttman, M.1
Léger, G.2
Cedarbaum, J.M.3
Reches, A.4
Woodward, W.5
Evans, A.6
Diksic, M.7
Gjedde, A.8
-
14
-
-
0027223850
-
Administration of the new COMT inhibitor OR-611 increases striatal uptake of fluorodopa
-
Guttman, M., Léger, G., Reches, A., Evans, A., Kuwabara, H., Cedarbaum, J.M., and Gjedde, A. (1993) Administration of the new COMT inhibitor OR-611 increases striatal uptake of fluorodopa. Mov. Disord., 8:298-304.
-
(1993)
Mov. Disord.
, vol.8
, pp. 298-304
-
-
Guttman, M.1
Léger, G.2
Reches, A.3
Evans, A.4
Kuwabara, H.5
Cedarbaum, J.M.6
Gjedde, A.7
-
15
-
-
84996123514
-
Selegiline in the treatment of daily fluctuations in disability of parkinsonian patients with long-term levodopa treatment
-
Heinonen, E.H., Rinne, U.K., and Tuominen, J. (1989) Selegiline in the treatment of daily fluctuations in disability of parkinsonian patients with long-term levodopa treatment. Acta Neurol. Scand., 126:113-118.
-
(1989)
Acta Neurol. Scand.
, vol.126
, pp. 113-118
-
-
Heinonen, E.H.1
Rinne, U.K.2
Tuominen, J.3
-
16
-
-
0014082977
-
Parkinsonism: Onset, progression, and mortality
-
Hoehn, M.M., and Yahr, M.D. (1967) Parkinsonism: Onset, progression, and mortality. Neurology, 17:427-442.
-
(1967)
Neurology
, vol.17
, pp. 427-442
-
-
Hoehn, M.M.1
Yahr, M.D.2
-
17
-
-
25944473092
-
Effects of simultaneous inhibition of MAO-B and COMT on striatal L-6-fluorodopa kinetics in non-human primates
-
L.-M. Voipio-Pulkki and U. Wegelius, eds. Gillot Oy, Turku, Finland
-
Holden, J.E., Pate, B.D., Snow, B.J., Chan, G.L.-Y., Chutskoff, T.L., Endres, C.E., Ruth, T.J., and Calne, D.B. (1992) Effects of simultaneous inhibition of MAO-B and COMT on striatal L-6-fluorodopa kinetics in non-human primates. In: Medical Application of Cyclotrons VI. L.-M. Voipio-Pulkki and U. Wegelius, eds. Gillot Oy, Turku, Finland, pp. A89-A90.
-
(1992)
Medical Application of Cyclotrons VI
-
-
Holden, J.E.1
Pate, B.D.2
Snow, B.J.3
Chan, G.L.-Y.4
Chutskoff, T.L.5
Endres, C.E.6
Ruth, T.J.7
Calne, D.B.8
-
19
-
-
0029785290
-
Fluorodopa positron emission tomography with an inhibitor of catechol-O-methyltransferase: Effect of the plasma 3-O-methyldopa fraction on data analysis
-
Ishikawa, T., Dhawan, V., Chaly, T., Robeson, W., Belakhlef, A., Mandel, F., Dahl, R., Margouleff, C., and Eidelberg, D. (1996) Fluorodopa positron emission tomography with an inhibitor of catechol-O-methyltransferase: Effect of the plasma 3-O-methyldopa fraction on data analysis. J. Cereb. Blood Flow Metab., 16:854-863.
-
(1996)
J. Cereb. Blood Flow Metab.
, vol.16
, pp. 854-863
-
-
Ishikawa, T.1
Dhawan, V.2
Chaly, T.3
Robeson, W.4
Belakhlef, A.5
Mandel, F.6
Dahl, R.7
Margouleff, C.8
Eidelberg, D.9
-
20
-
-
0027935135
-
General properties and clinical possibilities of new selective inhibitors of catechol O-methyltransferase
-
Kaakkola, S., Gordin, A., and Männistö, P.T. (1994) General properties and clinical possibilities of new selective inhibitors of catechol O-methyltransferase. Gen. Pharmac. Rev., 25:813-824.
-
(1994)
Gen. Pharmac. Rev.
, vol.25
, pp. 813-824
-
-
Kaakkola, S.1
Gordin, A.2
Männistö, P.T.3
-
21
-
-
0023502710
-
R) facilitates the activity of the nigrostriatal dopaminergic neuron
-
R) facilitates the activity of the nigrostriatal dopaminergic neuron. J. Neural. Transm. Suppl., 25:45-66.
-
(1987)
J. Neural. Transm. Suppl.
, vol.25
, pp. 45-66
-
-
Knoll, J.1
-
22
-
-
0015089408
-
The metabolism of L-3-O-methyldopa, a precursor of dopa in man
-
Kuruma, I., Bartholini, G., Tissot, R., and Pletscher, A. (1971) The metabolism of L-3-O-methyldopa, a precursor of dopa in man. Clin. Pharmacol. Ther., 12:678-682.
-
(1971)
Clin. Pharmacol. Ther.
, vol.12
, pp. 678-682
-
-
Kuruma, I.1
Bartholini, G.2
Tissot, R.3
Pletscher, A.4
-
24
-
-
0027455623
-
18F]fluoro-DOPA and positron emission tomography: Error analysis and application to normal subjects
-
18F]fluoro-DOPA and positron emission tomography: Error analysis and application to normal subjects. J. Cereb. Blood Flow Metab., 13:43-56.
-
(1993)
J. Cereb. Blood Flow Metab.
, vol.13
, pp. 43-56
-
-
Kuwabara, H.1
Cumming, P.2
Reith, J.3
Léger, G.4
Diksic, M.5
Evans, A.C.6
Gjedde, A.7
-
25
-
-
0029001883
-
Regional striatal DOPA transport and decarboxylase activity in Parkinson's disease
-
Kuwabara, H., Cumming, P., Yasuhara, Y., Léger, G.C., Guttman, M., Diksic, M., Evans, A.C., and Gjedde, A. (1995) Regional striatal DOPA transport and decarboxylase activity in Parkinson's disease. J. Nucl. Med., 36:1226-1231.
-
(1995)
J. Nucl. Med.
, vol.36
, pp. 1226-1231
-
-
Kuwabara, H.1
Cumming, P.2
Yasuhara, Y.3
Léger, G.C.4
Guttman, M.5
Diksic, M.6
Evans, A.C.7
Gjedde, A.8
-
26
-
-
0026609925
-
18F]-6-fluorodopa PET scanning in Parkinson's disease after selective COMT inhibition with nitecapone (OR-462)
-
18F]-6-fluorodopa PET scanning in Parkinson's disease after selective COMT inhibition with nitecapone (OR-462). Neurology, 42:199-203.
-
(1992)
Neurology
, vol.42
, pp. 199-203
-
-
Laihinen, A.1
Rinne, J.O.2
Rinne, U.K.3
Haaparanta, M.4
Ruotsalainen, U.5
Bergman, J.6
Solin, O.7
-
27
-
-
0026564087
-
Specific irreversible monoamine oxidase B inhibitors stimulate gene expression of aromatic L-amino acid decarboxylase in PC12 cells
-
Li, X.-M., Juorio, A.V., Paterson, I.A., Zhu, M.-Y., and Boulton, A.A. (1992) Specific irreversible monoamine oxidase B inhibitors stimulate gene expression of aromatic L-amino acid decarboxylase in PC12 cells. J. Neurochem., 59:2324-2327.
-
(1992)
J. Neurochem.
, vol.59
, pp. 2324-2327
-
-
Li, X.-M.1
Juorio, A.V.2
Paterson, I.A.3
Zhu, M.-Y.4
Boulton, A.A.5
-
28
-
-
1842348586
-
Comparison between selegiline and placebo in combination with L-dopa and entacapone in Parkinson's disease (PD)
-
Lyytinen, J., Kaakkola, S., Teräväinen, H., Ahtila, S., Naukkarinen, T., and Gordin, A. (1994) Comparison between selegiline and placebo in combination with L-dopa and entacapone in Parkinson's disease (PD). Mov. Disord. Abstr., 9:82.
-
(1994)
Mov. Disord. Abstr.
, vol.9
, pp. 82
-
-
Lyytinen, J.1
Kaakkola, S.2
Teräväinen, H.3
Ahtila, S.4
Naukkarinen, T.5
Gordin, A.6
-
29
-
-
0027329960
-
18F]fluoro-L-dihydroxyphenylalanine metabolism and positron emission tomography after catechol-O-methyltransferase inhibition in normal and hemiparkinsonian monkeys
-
18F]fluoro-L-dihydroxyphenylalanine metabolism and positron emission tomography after catechol-O-methyltransferase inhibition in normal and hemiparkinsonian monkeys. Brain Res., 626:1-13.
-
(1993)
Brain Res.
, vol.626
, pp. 1-13
-
-
Miletich, R.S.1
Comi, G.2
Bankiewicz, K.3
Plunkett, R.4
Adams, R.5
DiChiro, G.6
Kopin, I.J.7
-
31
-
-
0029416898
-
Inhibition of MAO-B by (-)-deprenyl alters dopamine metabolism in the macaque (Macaca facicularis) brain
-
Paterson, I.A., Davis, B.A., Durden, D.A., Juorio, A.V., Yu, P.H., Ivy, G., Milgram, W., Mendonca, A., Wu, P., and Boulton, A.A. (1995) Inhibition of MAO-B by (-)-deprenyl alters dopamine metabolism in the macaque (Macaca facicularis) brain. Neurochem. Res., 20: 1503-1510.
-
(1995)
Neurochem. Res.
, vol.20
, pp. 1503-1510
-
-
Paterson, I.A.1
Davis, B.A.2
Durden, D.A.3
Juorio, A.V.4
Yu, P.H.5
Ivy, G.6
Milgram, W.7
Mendonca, A.8
Wu, P.9
Boulton, A.A.10
-
32
-
-
0022389649
-
Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data. Generalizations
-
Patlak, C.S., and Blasberg, R.G. (1985) Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data. Generalizations. J. Cereb. Blood Flow Metab., 5:584-590.
-
(1985)
J. Cereb. Blood Flow Metab.
, vol.5
, pp. 584-590
-
-
Patlak, C.S.1
Blasberg, R.G.2
-
33
-
-
0020956774
-
Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data
-
Patlak, C.S., Blasberg, R.G., and Fenstermacher, J.D. (1983) Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data. J. Cereb. Blood Flow Metab., 3:1-7.
-
(1983)
J. Cereb. Blood Flow Metab.
, vol.3
, pp. 1-7
-
-
Patlak, C.S.1
Blasberg, R.G.2
Fenstermacher, J.D.3
-
34
-
-
0022496317
-
Monoamine oxidase activity and monoamine metabolism in brains of parkinsonian patients treated with l-deprenyl
-
Riederer, P., and Youdim, M.B.H. (1986) Monoamine oxidase activity and monoamine metabolism in brains of parkinsonian patients treated with l-deprenyl. J. Neurochemistry, 46:1359-1365.
-
(1986)
J. Neurochemistry
, vol.46
, pp. 1359-1365
-
-
Riederer, P.1
Youdim, M.B.H.2
-
35
-
-
0029417246
-
18F]fluorodopa utilization after COMT inhibition with entacapone studied with PET in advanced Parkinson's disease
-
18F]fluorodopa utilization after COMT inhibition with entacapone studied with PET in advanced Parkinson's disease. J. Neural Transm. Park. Dis. Dement. Sect., 10:91-106.
-
(1995)
J. Neural Transm. Park. Dis. Dement. Sect.
, vol.10
, pp. 91-106
-
-
Ruottinen, H.M.1
Rinne, J.O.2
Ruotsalainen, U.H.3
Bergman, J.R.4
Oikonen, V.J.5
Haaparanta, M.T.6
Solin, O.H.7
Laihinen, A.O.8
Rinne, U.K.9
-
36
-
-
0028128512
-
18F]-6-L-fluorodopa metabolism: Implications for levodopa therapy of Parkinson's disease
-
18F]-6-L-fluorodopa metabolism: Implications for levodopa therapy of Parkinson's disease. Neurology, 44:1292-1297.
-
(1994)
Neurology
, vol.44
, pp. 1292-1297
-
-
Sawle, G.V.1
Burn, D.J.2
Morrish, P.K.3
Lammertsma, A.A.4
Snow, B.J.5
Luthra, S.6
Osman, S.7
Brooks, D.J.8
-
37
-
-
0006944936
-
The effect of tolcapone on central and peripheral COMT activity in normal humans and Parkinson's disease: A PET study
-
Snow, B.J., Vingerhoets, F.J.G., Holden, J.E., Sossi, V., Chan, G.L.Y., Buckley, K.R., Morrison, K.S., Ruth, T., Jorga, K., Pedder, S., and Dingemanse, J. (1996) The effect of tolcapone on central and peripheral COMT activity in normal humans and Parkinson's disease: A PET study. Mov. Disord. Abst., 11:195.
-
(1996)
Mov. Disord. Abst.
, vol.11
, pp. 195
-
-
Snow, B.J.1
Vingerhoets, F.J.G.2
Holden, J.E.3
Sossi, V.4
Chan, G.L.Y.5
Buckley, K.R.6
Morrison, K.S.7
Ruth, T.8
Jorga, K.9
Pedder, S.10
Dingemanse, J.11
-
38
-
-
0024151927
-
Effect of MAO inhibitors on the uptake and metabolism of dopamine in rat and human brain
-
Tekes, K., Tóthfalusi, L., Gaál, J., and Magyar, K. (1988) Effect of MAO inhibitors on the uptake and metabolism of dopamine in rat and human brain. Pol. J. Pharmacol. Pharm., 40:653-658.
-
(1988)
Pol. J. Pharmacol. Pharm.
, vol.40
, pp. 653-658
-
-
Tekes, K.1
Tóthfalusi, L.2
Gaál, J.3
Magyar, K.4
-
39
-
-
0027051257
-
Chronic selegiline administration transiently decreases tyrosine hydroxylase activity and mRNA in the rat nigrostriatal pathway
-
Vrana, S.L., Azzaro, A.J., and Vrana, K.E. (1992) Chronic selegiline administration transiently decreases tyrosine hydroxylase activity and mRNA in the rat nigrostriatal pathway. Mol. Pharmacol., 41:839-844.
-
(1992)
Mol. Pharmacol.
, vol.41
, pp. 839-844
-
-
Vrana, S.L.1
Azzaro, A.J.2
Vrana, K.E.3
-
40
-
-
0016707704
-
3-O-methyldopa uptake and inhibition of L-dopa at the blood-brain barrier
-
Wade, L.A., and Katzman, R. (1975) 3-O-methyldopa uptake and inhibition of L-dopa at the blood-brain barrier. Life Sci., 17:131-136.
-
(1975)
Life Sci.
, vol.17
, pp. 131-136
-
-
Wade, L.A.1
Katzman, R.2
-
41
-
-
0022495911
-
The effect of repeated doses of(-)deprenyl on the dynamics of monoaminergic transmission. Comparison with clorgyline
-
Zsilla, G., Földi, P., Held, G., Székely, A.M., and Knoll, J. (1986) The effect of repeated doses of(-)deprenyl on the dynamics of monoaminergic transmission. Comparison with clorgyline. Pol. J. Pharmacol. Pharm., 38:57-67.
-
(1986)
Pol. J. Pharmacol. Pharm.
, vol.38
, pp. 57-67
-
-
Zsilla, G.1
Földi, P.2
Held, G.3
Székely, A.M.4
Knoll, J.5
|