Synthesis of [11 C-methyl]-(-)-OSU6162, its regional brain distribution and some pharmacological effects of (-)- OSU6162 on the dopaminergic system studied in the rhesus monkey by positron emission tomography

Nuclear Medicine and Biology

Volumn 24, Issue 6, 1997, Pages 507-511

  Neu, Henrik ^a   Hartvig, Per ^a   Torstenson, Richard ^a   Fasth, Karl Johan ^a   Sonesson, Clas ^b   Waters, Nicholas ^b   Carlsson, Arvid ^b   Tedroff, Joakim ^b   Långström, Bengt ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b Uppsala University PET Centre ^*

Author keywords

11C Methyl OSU6162; Monkeys; PET; Presynaptic dopaminergic antagonist

Indexed keywords

3 (1 PROPYLPIPERIDIN 3 YL)BENZENETHIOL; 3 [3 (METHYLSULFONYL)PHENYL] 1 PROPYLPIPERIDINE; 3 [3 (METHYLSULFONYL)PHENYL] 1 PROPYLPIPERIDINE C 11; CARBON 11; DOPAMINE RECEPTOR BLOCKING AGENT; OSU 1281; RACLOPRIDE; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG; CARBON; DOPAMINE; PIPERIDINE DERIVATIVE; SALICYLAMIDE DERIVATIVE;

ANIMAL EXPERIMENT; ARTICLE; DOPAMINERGIC SYSTEM; DOSE RESPONSE; DRUG BRAIN LEVEL; DRUG DISTRIBUTION; DRUG SYNTHESIS; FEMALE; INTRAVENOUS DRUG ADMINISTRATION; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; RHESUS MONKEY; ANIMAL; BRAIN; COMPUTER ASSISTED EMISSION TOMOGRAPHY; MACACA; METABOLISM; SYNTHESIS;

ANIMALS; BRAIN; CARBON RADIOISOTOPES; DOPAMINE; DOPAMINE ANTAGONISTS; FEMALE; MACACA MULATTA; PIPERIDINES; RACLOPRIDE; SALICYLAMIDES; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 0030608883     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-8051(97)00023-1     Document Type: Article

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