메뉴 건너뛰기




Volumn 38, Issue 6, 1997, Pages 896-906

Dynamic 13C NMR analysis of pyruvate and lactate oxidation in the in vivo canine myocardium: Evidence of reduced utilization with increased work

Author keywords

Carbon 13; Krebs cycle; Nuclear magnetic resonance; Substrate selection

Indexed keywords

AMINO ACIDS; LAKES; NUCLEAR MAGNETIC RESONANCE; OXIDATION; SUBSTRATES;

EID: 0030608755     PISSN: 07403194     EISSN: None     Source Type: Journal    
DOI: 10.1002/mrm.1910380608     Document Type: Article
Times cited : (7)

References (43)
  • 1
    • 0004364201 scopus 로고
    • The metabolism of the heart
    • R. J. Bing, The metabolism of the heart. Harvey Lecture Series 50, 27-70 (1956).
    • (1956) Harvey Lecture Series , vol.50 , pp. 27-70
    • Bing, R.J.1
  • 2
    • 0344695573 scopus 로고
    • Unesterified fatty acid in human blood plasma. II. The transport function of unesterified fatty acid
    • R. S. Gordon, A. Cherkes, Unesterified fatty acid in human blood plasma. II. The transport function of unesterified fatty acid. J. Clin. Invest. 36, 810-815 (1957).
    • (1957) J. Clin. Invest. , vol.36 , pp. 810-815
    • Gordon, R.S.1    Cherkes, A.2
  • 3
    • 33744991595 scopus 로고
    • Fatty acid and glucose metabolism in the perfused heart
    • J. C. Shipp, L. H. Opie, D. C. Challoner, Fatty acid and glucose metabolism in the perfused heart. Nature 189, 1018-1019 (1961).
    • (1961) Nature , vol.189 , pp. 1018-1019
    • Shipp, J.C.1    Opie, L.H.2    Challoner, D.C.3
  • 4
    • 0015349584 scopus 로고
    • The effects of increased heart work on the tricarboxylate cycle and its interactions with glycolysis in the perfused rat heart
    • J. R. Neeley, R. M. Denton, P. J. England, P. J. Randle, The effects of increased heart work on the tricarboxylate cycle and its interactions with glycolysis in the perfused rat heart. Biochem. J. 128, 147-159 (1972).
    • (1972) Biochem. J. , vol.128 , pp. 147-159
    • Neeley, J.R.1    Denton, R.M.2    England, P.J.3    Randle, P.J.4
  • 5
    • 0001754053 scopus 로고
    • Acetoacetate as fuel of respiration in the perfused rat heart
    • J. R. Williamson, H. A. Krebs, Acetoacetate as fuel of respiration in the perfused rat heart. Biochem. J. 80, 540-547 (1961).
    • (1961) Biochem. J. , vol.80 , pp. 540-547
    • Williamson, J.R.1    Krebs, H.A.2
  • 6
    • 0014077344 scopus 로고
    • Effect of pressure development on oxygen consumption by isolated rat heart
    • J. R. Neeley, H. Liebermeister, E. J. Battersby, H. E. Morgan, Effect of pressure development on oxygen consumption by isolated rat heart. Am. J. Physiol. 212, 804-814 (1967).
    • (1967) Am. J. Physiol. , vol.212 , pp. 804-814
    • Neeley, J.R.1    Liebermeister, H.2    Battersby, E.J.3    Morgan, H.E.4
  • 7
    • 0014077345 scopus 로고
    • Effect of pressure development of membrane transport of glucose in isolated rat heart
    • J. R. Neeley, H. Liebermeister, H. E. Morgan,. Effect of pressure development of membrane transport of glucose in isolated rat heart. Am. J. Physiol. 212, 815-822 (1967).
    • (1967) Am. J. Physiol. , vol.212 , pp. 815-822
    • Neeley, J.R.1    Liebermeister, H.2    Morgan, H.E.3
  • 8
    • 0011170654 scopus 로고
    • Effect of pyruvate and acetoacetate on the metabolism of fatty acids by the perfused rat heart
    • R. E. Olson, Effect of pyruvate and acetoacetate on the metabolism of fatty acids by the perfused rat heart. Nature 195, 597-599 (1962).
    • (1962) Nature , vol.195 , pp. 597-599
    • Olson, R.E.1
  • 9
    • 0021240563 scopus 로고
    • Adequacy of oxygenation of isolated perfused rat heart
    • L. H. Opie, Adequacy of oxygenation of isolated perfused rat heart. Basic Res. Cardiol. 79, 300-306 (1984).
    • (1984) Basic Res. Cardiol. , vol.79 , pp. 300-306
    • Opie, L.H.1
  • 10
    • 0018862072 scopus 로고
    • Utilization of energy-providing substrates in the isolated working rat heart
    • H. Taegmeyer, R. Hems, H. A. Krebs, Utilization of energy-providing substrates in the isolated working rat heart. Biochem. J. 186, 701-711 (1980).
    • (1980) Biochem. J. , vol.186 , pp. 701-711
    • Taegmeyer, H.1    Hems, R.2    Krebs, H.A.3
  • 11
    • 8244254791 scopus 로고
    • The effects of short-chain fatty acids and starvation on the metabolism of glucose and lactate by the perfused guinea pig heart
    • E. J. Davis, J. H. Quastel, The effects of short-chain fatty acids and starvation on the metabolism of glucose and lactate by the perfused guinea pig heart. Can. J. Biochem. 42, 1605-1621 (1964).
    • (1964) Can. J. Biochem. , vol.42 , pp. 1605-1621
    • Davis, E.J.1    Quastel, J.H.2
  • 12
    • 0020186777 scopus 로고
    • Computer simulation of metabolism of glucose-perfused rat heart in a work jump
    • M. J. Achs, D. Garfinkel, L. H. Opie, Computer simulation of metabolism of glucose-perfused rat heart in a work jump. Am. J. Physiol. 243, R389-R399 (1982).
    • (1982) Am. J. Physiol. , vol.243
    • Achs, M.J.1    Garfinkel, D.2    Opie, L.H.3
  • 20
    • 0025922292 scopus 로고
    • 13C NMR spectra of intact hearts under conditions of varied metabolite enrichment
    • 13C NMR spectra of intact hearts under conditions of varied metabolite enrichment. Magn. Reson. Med. 19, 186-190 (1991).
    • (1991) Magn. Reson. Med. , vol.19 , pp. 186-190
    • Lewandowski, E.D.1    Hulbert, C.2
  • 21
    • 0026565266 scopus 로고
    • Nuclear magnetic resonance evaluation of metabolic and respiratory support of workload in intact rabbit hearts
    • E. D. Lewandowski, Nuclear magnetic resonance evaluation of metabolic and respiratory support of workload in intact rabbit hearts. Circ. Res. 70, 576-582 (1992).
    • (1992) Circ. Res. , vol.70 , pp. 576-582
    • Lewandowski, E.D.1
  • 22
    • 43949150714 scopus 로고
    • Energy metabolism of the heart: From basic concepts to clinical applications
    • H. Taegmeyer, Energy metabolism of the heart: from basic concepts to clinical applications. Curr. Probl. Cardiol. 19, 57-116 (1994).
    • (1994) Curr. Probl. Cardiol. , vol.19 , pp. 57-116
    • Taegmeyer, H.1
  • 24
    • 0023221917 scopus 로고
    • Delineation of myocardial oxygen utilization with carbon-11-labeled acetate
    • M. Brown, D. R. Marshall, B. E. Sobel, S. R. Bergman, Delineation of myocardial oxygen utilization with carbon-11-labeled acetate. Circulation 76, 687-696 (1987).
    • (1987) Circulation , vol.76 , pp. 687-696
    • Brown, M.1    Marshall, D.R.2    Sobel, B.E.3    Bergman, S.R.4
  • 25
    • 0023777664 scopus 로고
    • Radiolabeled acetate as a tracer of myocardial tricarboxylic acid cycle flux
    • D. B. Buxton, M. Schwaiger, A. Nguyen, M. E. Phelps. H. R. Schelbert, Radiolabeled acetate as a tracer of myocardial tricarboxylic acid cycle flux. Circ. Res. 63, 628-634 (1988).
    • (1988) Circ. Res. , vol.63 , pp. 628-634
    • Buxton, D.B.1    Schwaiger, M.2    Nguyen, A.3    Phelps, M.E.4    Schelbert, H.R.5
  • 26
    • 0242700442 scopus 로고
    • Acetyl-CoA synthetase
    • L. T. Webster, Acetyl-CoA synthetase. Meth. Enzymol. 13, 375-381 (1969).
    • (1969) Meth. Enzymol. , vol.13 , pp. 375-381
    • Webster, L.T.1
  • 27
    • 0024452528 scopus 로고
    • The pharmacology of dichloroacetate
    • P. W. Stacpoole, The pharmacology of dichloroacetate. Metabolism 38, 1124-1144 (1989).
    • (1989) Metabolism , vol.38 , pp. 1124-1144
    • Stacpoole, P.W.1
  • 28
    • 0026937020 scopus 로고
    • Improved cardiac gating and ventilation timing in animal experiments
    • J. Pruski, A. Abduljalil, P-M. L. Robitaille. Improved cardiac gating and ventilation timing in animal experiments. Magn. Reson. Med. 27, 329-337 (1991).
    • (1991) Magn. Reson. Med. , vol.27 , pp. 329-337
    • Pruski, J.1    Abduljalil, A.2    Robitaille, P.-M.L.3
  • 29
    • 0009578882 scopus 로고
    • General solutions for tailored modulation profiles in adiabatic excitation
    • T. E. Skinner, P. M. L. Robitaille, General solutions for tailored modulation profiles in adiabatic excitation. J. Magn. Reson. 98, 14-23 (1992).
    • (1992) J. Magn. Reson. , vol.98 , pp. 14-23
    • Skinner, T.E.1    Robitaille, P.M.L.2
  • 30
    • 0001271104 scopus 로고
    • Uniform sample excitation with surface coils for in vivo spectroscopy by adiabatic rapid half-passage
    • M. R. Bendall, D. T. Pegg. Uniform sample excitation with surface coils for in vivo spectroscopy by adiabatic rapid half-passage. J. Magn. Reson. 67, 376-381 (1986).
    • (1986) J. Magn. Reson. , vol.67 , pp. 376-381
    • Bendall, M.R.1    Pegg, D.T.2
  • 32
    • 0001722494 scopus 로고
    • 1 insensitive adiabatic RF pulses
    • (J. Seelig, M. Rudin, Eds), Springer-Verlag, Berlin
    • 1 insensitive adiabatic RF pulses, in "NMR: Basic Principles and Progress" (J. Seelig, M. Rudin, Eds), Vol. 26, pp.109-147, Springer-Verlag, Berlin, 1992.
    • (1992) NMR: Basic Principles and Progress , vol.26 , pp. 109-147
    • Garwood, M.1    Ugurbil, K.2
  • 35
    • 0026024570 scopus 로고
    • Fatty acid metabolism and contractile function in the reperfused myocardium: Multinuclear NMR studies of isolated rabbit hearts
    • D. L. Johnston, E. D. Lewandowski, Fatty acid metabolism and contractile function in the reperfused myocardium: multinuclear NMR studies of isolated rabbit hearts. Circ. Res. 68, 714-725 (1992).
    • (1992) Circ. Res. , vol.68 , pp. 714-725
    • Johnston, D.L.1    Lewandowski, E.D.2
  • 39
    • 0000430925 scopus 로고
    • Glycolytic control mechanisms
    • J. R. Williamson, Glycolytic control mechanisms. J. Biol. Chem. 240, 2308-2321 (1965).
    • (1965) J. Biol. Chem. , vol.240 , pp. 2308-2321
    • Williamson, J.R.1
  • 42
    • 0020345070 scopus 로고
    • Pyruvate dehydrogenase complex from bovine kidney and heart
    • F. H. Pettit, L. J. Reed, Pyruvate dehydrogenase complex from bovine kidney and heart. Meth. Enzymol. 89, 376-336 (1982).
    • (1982) Meth. Enzymol. , vol.89 , pp. 376-1336
    • Pettit, F.H.1    Reed, L.J.2
  • 43
    • 0014350358 scopus 로고
    • Reinigung und kristallisation der thiolase. untersuchungen zum wirkungsmechanismus
    • U. Gehring, C. Riepertinger, F. Lynen, Reinigung und kristallisation der thiolase. untersuchungen zum wirkungsmechanismus. Eur. J. Biochem. 6, 264-280 (1968).
    • (1968) Eur. J. Biochem. , vol.6 , pp. 264-280
    • Gehring, U.1    Riepertinger, C.2    Lynen, F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.