Phosphonates as 31P-NMR markers of extra- and intracellular space and pH in perfused rat liver

NMR in Biomedicine

Volumn 10, Issue 6, 1997, Pages 263-270

  Bruynseels, Koenraad ^a   Gillis, Nanna ^a   Van Hecke, Paul ^a   Vanstapel, Florent ^a  

^a UNIVERSITY HOSPITALS LEUVEN   (Belgium)

Author keywords

Compartments; Markers; PH; Transport; Volume

Indexed keywords

AMMONIUM CHLORIDE; CREATINE PHOSPHATE; PHENYLPHOSPHONIC ACID; PHOSPHATE; PHOSPHONIC ACID DERIVATIVE; PHOSPHORUS 31; UNCLASSIFIED DRUG; AMINOPROPYLPHOSPHONATE; BIOLOGICAL MARKER; METHYLPHOSPHONIC ACID; ORGANOPHOSPHORUS COMPOUND; PROPYLAMINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL PH; CELL VOLUME; CONTROLLED STUDY; EXTRACELLULAR SPACE; INTERNALIZATION; LIVER PERFUSION; MALE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; RAT; ANIMAL; CYTOSOL; HEPATOBILIARY SYSTEM; INTRACELLULAR FLUID; LIVER; METABOLISM; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE; PERFUSION; PH; WISTAR RAT;

ANIMALS; BILIARY TRACT; BIOLOGICAL MARKERS; CYTOSOL; EXTRACELLULAR SPACE; HYDROGEN-ION CONCENTRATION; INTRACELLULAR FLUID; LIVER; MALE; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; ORGANOPHOSPHORUS COMPOUNDS; PERFUSION; PHOSPHONIC ACIDS; PROPYLAMINES; RATS; RATS, WISTAR;

EID: 0030608667     PISSN: 09523480     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-1492(199709)10:6<263::AID-NBM472>3.0.CO;2-J     Document Type: Article

References (36)

1. Potts, J. R., Kirk, K. and Kuchel, P. W. Characterization of the transport of the nonelectrolyte dimethyl methylphosphonate across the red cell membrane. NMR Biomed. 1, 198-204 (1989).
2. 31P-NMR procedure. J. Magn. Res. 62, 568-572 (1985).
3. 31P NMR spectroscopy. 7th Annual Meeting of the European Society for Magnetic Resonance in Medicine and Biology. Abstr., p. 305 (1990).
4. 31P NMR spectroscopy and phosphonate markers. Magn. Resort. Med. 32, 181-188 (1994).
5. 23Na MRS. Fourth Scientific Meeting of the International Society of Magnetic Resonance in Medicine. Abstr., p. 1042 (1996).
6. 31P-nuclear magnetic resonance analysis of perfused single frog skins. Am. J. Physiol. 248, C177-C180 (1985).
7. Meyer, R. A., Brown, T. R. and Kushmerick, M. J. Phosphorus nuclear magnetic resonance of fast- and slow-twitch muscle. Am. J. Physiol. 248, C279-C287 (1985).
8. 31P-NMR indicator of extracellular pH and volume in the isolated perfused rabbit bladder. Circ. Res. 60, 472-477 (1987).
9. 31P NMR study of the isolated rat heart. Seventh Annual Meeting of the Society of Magnetic Resonance in Medicine. Abstr., p. 665 (1988).
10. 31P NMR spectroscopic study of the isovolumic rat heart. NMR Biomed. 6, 278-286 (1993).
11. Stubbs, M., Rodrigues, L., Howe, F. A., Wang, J., Jeong, K., Veech, R. L. and Griffiths, J. R. Metabolic consequences of a reversed pH gradient in rat tumors. Canc. Res. 54, 4011-4016 (1994).
12. 31P NMR pH indicator. J. Biol. Chem. 262, 11,032-11,037 (1987).
13. Labotka, R. J. and Kleps, R. A. A phosphate-analogue probe of red cell pH using phosphorus-31 nuclear magnetic resonance. Biochemistry 22, 6089-6095 (1983).
14. 31P-NMR methylphosphonate procedure. Biochim. Biophys. Acta 885, 23-33 (1986).
15. Labotka, R. J. and Omachi, A. Erythrocyte anion transport of phosphate analogs. J. Biol. Chem. 262, 305-311 (1987).
16. Petzinger, E. Transport of organic anions in the liver. An update on bile acid, fatty acid, monocarboxylate, anionic amino acid, cholephilic organic anion, and anionic drug transport. Rev. Physiol. Biochem. Pharmacol. 123, 47-211 (1994).
17. 31P NMR Magn. Res. Med. 4, 244-251 (1987).
18. 31P NMR. J. Anal. Toxicol. 12, 284-286 (1988).
19. 31P-NMR markers of the extracellular space? A study in perfused rat liver. Third Scientific Meeting of the Society of Magnetic Resonance. Abstr., p. 1657 (1995).
20. Vanstapel, F., Waebens, M., Van Hecke, P., Decanniere, C. and Stalmans, W. The cytosolic concentration of phosphate determines the maximal rate of glycogenolysis in perfused rat liver. Biochem. J. 266, 207-212 (1990).
21. Führ, J., Kaczmarczyk, J. and Krüttgen, C.-D. Eine einfache colorimetrische Methode zur Inulinbestimmung für Nieren-clearance-untersuchungen bei Stoffwechselgesunden und Diabetikern. Klin. Wochenschr. 33, 729-730 (1955).
22. Van Hecke, P., Decanniere, C. and Vanstapel, F. Double-tuned resonator designs for NMR spectroscopy. J. Magn. Reson. 84, 170-176 (1989).
23. 31P NMR signals using the variable projection method and prior knowledge. Magn. Reson. Med. 6, 92-98 (1988).
24. Cabañas, M. and van den Boogaart, A. www:http://rmn3.ua-b.es.mruiwww/mrui_hom.html (1996).
25. Vold, R. L., Waugh, J. S., Klein, M. P. and Phelps, D. E. Measurement of spin relaxation in complex systems. J. Chem. Phys. 48, 3831-3833 (1968).
26. Kotyk, A. and Janáček, K. Kinetics of tracer exchange. In Cell Membrane Transport. Principles and Techniques, ed. by Kotyk, A. and K. Janàček, pp. 159-180. Plenum, New York (1975).
27. Ernst, R. R. and Anderson, W. A. Application of Fourier transform spectroscopy to magnetic resonance. Rev. Sci. Instrum. 37, 93-102 (1966).
28. Alpini, G., Garrik, R. A., Jones, M. J. T., Nunes, R. and Tavoloni, N. Water and nonelectrolyte permeability in isolated rat hepatocytes. Am. J. Physiol. 251, C872-C882 (1986).
29. 31phosphorus nuclear magnetic resonance study. Biochem. J. 192, 191-202 (1980).
30. 31P NMR chemical shifts of various phosphoryl compounds. Biochemistry 27, 8803-8810 (1988).
31. Lake, J. R., Ličko, V., Van Dyke, R. W. and Scharschmidt, B. F. Biliary secretion of fluid-phase markers by the isolated perfused rat liver. J. Clin. Invest. 76, 676-684 (1985).
32. Felberbauer, F. X. and Graf, J. Fiber-optic measurement of intracellular pH in intact rat liver using pH-sensitive dyes. Pflügers Arch. 419, 215-217 (1991).
33. + metabolism and the intracellular pH in isolated perfused rat liver. Biochem. J. 293, 667-673 (1993).
34. 31P-NMR spectra at low magnetic field strengths. Biochim. Biophys. Acta 1111, 51-58 (1992).
35. 31P-MRS measurements of extracellular pH of tumors using 3-aminopropylphosphonate. Am. J. Physiol. 267, C195-C203 (1994).
36. 31P-NMR. 13th Annual meeting of the European Society for Magnetic Resonance in Medicine and Biology. Abstr., p. 325-326 (1996).