Activation of nitric oxide synthase gene expression by hypoxia in central and peripheral neurons

Molecular Brain Research

Volumn 43, Issue 1-2, 1996, Pages 341-346

  Prabhakar, Nanduri R ^a   Pieramici, Sean F ^a   Premkumar, Daniel R D ^a   Kumar, Ganesh K ^a   Kalaria, Rajesh N ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cardio respiratory system; Cerebellum; Chronic hypoxia; Nitric oxide; Nitric oxide synthase; Nodose ganglion

Indexed keywords

BETA ACTIN; MESSENGER RNA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BRAIN NERVE CELL; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVITY; FEMALE; GENE ACTIVATION; HYPOXIA; MALE; NODOSE GANGLION; NONHUMAN; PERIPHERAL NERVOUS SYSTEM; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALIA;

EID: 0030608521     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-328X(96)00222-7     Document Type: Article

References (19)

1. Aimi, Y., Fujimura, M., Vincent, S.R. and Kimura, H., Localization of NADPH-diaphorase containing neurons in sensory ganglia of the rat, J. Comp. Neurol., 306 (1991) 382-392.
2. Archer, S., Freude, K.A. and Schultz, P.J., Effect of graded hypoxia on the induction and function of inducible nitric oxide synthase in rat mesangial cells, Circ. Res., 77 (1995) 21-28.
3. Berdt, D.S. and Snyder, S.H., Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme, Proc. Natl. Acad. Sci. USA, 87 (1990) 768-770.
4. Dinerman, J.L., Dawson, T.M., Schell, M.J., Snowman, A. and Snyder, S.H., Endothelial nitric oxide synthase localized to hippocampal pyramidal cells: implications for synaptic plasticity, Proc. Natl. Acad. Sci. USA, 91 (1994) 4214-4218.
5. Griffith, O.W. and Steuhr, D.J., Nitric oxide synthases: properties and catalytic mechanism, Annu. Rev. Physiol., 57 (1995) 707-736.
6. Kalaria, R.N., Golde, T. and Perry, G., The serine protease inhibitor antithrombin III and its mRNA in the pathogenesis of Alzheimer disease, Am. J. Pathol., 143 (1993) 886-893.
7. Lowry, O.H., Rosebrough, N.J., Farr, A.L. and Randall, R.J., Protein measurements with the Folin phenol reagent, J. Biol. Chem., 193 (1951)265-275.
8. McQuillan, L.P., Leung, G.K., Marsden, P.A., Kostyk, S.K. and Kourembanas, S., Hypoxia inhibits expression of eNOS via transcriptional and post-transcriptional mechanisms, Am. J. Physiol., 267 (1994) H1921-H1927.
9. Melillo, G., Musso, T., Sica, A., Taylor, L.S., Cox, G.W. and Varesio, L., A hypoxia-responsive element mediates a novel pathway of activation of the inducible nitric oxide synthase promoter, J. Exp. Med., 182 (1995) 1683-1693.
10. Millhorn, D.E., Czyzyk-Krzeska, M.F., Bayliss, D. and Lawson, E.E., Regulation of gene expression by hypoxia, Sleep, 16 (1993) S44-S48.
11. Moncada, S., Palmer, M.H. and Higgs, E.A., Nitric oxide: physiology, pathophysiology and pharmacology, Pharmacol. Rev., 43 (1991) 109-142.
12. Prabhakar, N.R., Cherniack, N.S. and Haxhiu, M.A., Inhibitory and excitatory effects of nitric oxide on respiratory response to hypoxia. In O. Trouth, R.M. Millis, H. Kiwull-Schone and M. Schlafke (Eds.), Ventral Brainstem Mechanisms and Control of Respiration and Blood Pressure. Lung Biology in Health and Decease Series, Vol. 82, Marcel Dekker, New York, 1995, pp. 393-404.
13. Prabhakar, N.R., Kumar, G.K., Chang, C.H., Agani, F.H. and Haxhiu, M.A., Nitric oxide in sensory function of the carotid body, Brain Res., 625 (1993) 16-22.
14. 2. In P. Zapata, C. Eyzaguirrie and R.W. Torrance (Eds.), Frontiers in Arterial Chemoreception, Plenum Press, New York, 1996 (in press).
15. Prabhakar, N.R., Shenoy, B.C., Simonson, M.S. and Cherniack, N.S., Cell selective induction and transcriptional activation of immediate early genes by hypoxia, Brain Res., 697 (1995) 266-270.
16. Premkumar, D.R.D., Smith, M.A., Richey, P.L., Petersen, R.B., Castellani, R., Kutty, R.K., Wiggert, B., Perry, G., Kalaria, R.N., Induction of heme oxygenase-1 mRNA and protein in neocortex and cerebral vessels in Alzheimer's disease, J. Neurochem., 65 (1995) 1399-1402.
17. Shaul, P.W., North, A.J., Brannan, T.S., Ujcic, K., Wells, L.B., Nisen, P.A., Lowenstein, C.J., Snyder, S.H. and Star, R.A., Prolonged in vivo hypoxia enhances nitric oxide synthase Type I and Type III gene expression in adult rat lung, Am. J. Resp. Cell Mol. Biol., 13 (1995) 167-174.
18. Shaul, P.W., North, A.J., Wu, L.C., Wells, L.B., Brannon, T.S., Lau, K.S., Michel, T., Margraf, L.B. and Star, R.A., Endothelial nitric oxide synthase is expressed in cultured human bronchial epithelium, J. Clin. Invest., 94 (1994) 2231-2236.
19. Snyder, S.H., Nitric oxide: first in a new class of neurotransmitters, Science, 257 (1992) 494-496.