Linkage of strain-specific nicotinic receptor α7, subunit restriction fragment length polymorphisms with levels of α-bungarotoxin binding in brain

Molecular Brain Research

Volumn 43, Issue 1-2, 1996, Pages 30-40

  Stitzel, Jerry A ^a   Farnham, Douglas A ^a   Collins, Allan C ^a  

^a UNIVERSITY OF COLORADO   (United States)

Author keywords

Genetics; Nicotinic receptor; Nicotinic receptor subunit; Restriction fragment length polymorphism; Seizure; bungarotoxin

Indexed keywords

ALPHA BUNGAROTOXIN; BRAIN RECEPTOR; COMPLEMENTARY DNA; NICOTINE; NICOTINIC RECEPTOR; RECEPTOR SUBUNIT; RNA;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GENOTYPE; MOLECULAR CLONING; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; POINT MUTATION; PRIORITY JOURNAL; RECEPTOR BINDING; RECEPTOR DENSITY; RECEPTOR GENE; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RNA ANALYSIS; SEIZURE SUSCEPTIBILITY; SEQUENCE HOMOLOGY;

ANIMALIA; MURINAE; RODENTIA;

EID: 0030608516     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-328X(96)00149-0     Document Type: Article

References (51)

1. Altschul, S.F., Gish, W., Miller, W., Myers, E.W. and Lipman, D.J., Basic logical alignment search tool, J. Mol. Biol., 215 (1990) 403-410.
2. Boulter, J., Connolly, J., Deneris, E. Goldman, D., Heinemann, S. and Patrick, J., Functional expression of two neuronal nicotinic acetlycholine receptors from cDNA clones identifies a family, Proc. Natl. Acad. Sci. USA, 84 (1987) 7763-7767.
3. Boulter, J., Evans, K., Goldman, D., Martin, G., Treco, D., Heinemann, S. and Patrick, J., Isolation of a cDNA clone coding for a possible neural nicotinic acetylcholine receptor α-subunit, Nature, 319 (1986) 368-374.
4. 3H]N-Methyl-carbamylcholine, a new radioligand specific for nicotinic acetylcholine receptors in brain, Eur. J. Pharmacol., 139 (1987) 323-333.
5. Chomczynski, P. and Sacchi, N., Single-step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction, Anal. Biochem., 162 (1987) 156-159.
6. 125I]α-bungarotoxin, J. Neurosci., 5 (1985) 1307-1315.
7. Couturier, S., Bertrand, D., Matter, J.-M., Hernandez, M.-C., Bertrand, S., Millar, N., Valera, S., Barkas, T. and Ballivet, M., A neuronal nicotinic acetylcholine receptor subunit (α7) is developmentally regulated and forms a homo-oligomeric channel blocked by α-Btx, Neuron, 5 (1990) 847-856.
8. 3: a new member of nicotinic acetylcholine receptor gene family is expressed in brain, J. Biol. Chem., 264 (1989) 6268-6272.
9. Deneris, E.S., Connolly, J., Boulter, J., Wada, E., Wada, K., Swanson, L., Patrick, J. and Heinemann, S., Primary structure and expression of β2: a novel subunit of neuronal nicotinic acetylcholine receptors, Neuron, 1 (1988) 45-54.
10. Duvoisin, R.M., Deneris, E.S., Patrick, J. and Heinemann, S., The functional diversity of the neuronal nicotinic acetylcholine receptors is increased by a novel subunit: β4, Neuron, 3 (1989) 487-496.
11. Elgoyhen, A.B., Johnson, D.S., Boulter, J., Vetter, D.E. and Heinemann, S., α9: an acetylcholine receptor with novel pharmacological properties expressed in rat cochlear hair cells, Cell, 79 (1994) 705-715.
12. Feinberg, A.P. and Vogelstein, B., A technique for radiolabelling DNA restriction endonuclease fragments to high specific activity, Anal. Biochem., 132 (1983) 6-13.
13. Flores, C.M., Rogers, S.W., Pabreza, L.A., Wolfe, B.B. and Kellar, K.J., A subtype of nicotinic cholinergic receptor in rat brain is composed of α4 and β2 subunits and is up-regulated by chronic nicotine treatment, Mol. Pharmacol., 41 (1992) 31-37.
14. Fornasari, D., Chini, B., Tarroni, C.P. and Clementi, F., Molecular cloning of human neuronal nicotinic receptor α3-subunit, Neurosci. Lett., 111 (1990) 351-356.
15. Hernandez, M., Erkman, L., Matter-Sadzinski, L., Roztocil, T., Ballivet, M. and Matter, J., Characterization of the nicotinic acetylcholine receptor β3 gene, J. Biol. Chem., 270 (1995) 3224-3233.
16. 3H]epibatidine binding to nicotinic cholinergic receptors in rat and human brain, Mol. Pharmacol., 48 (1995) 280-287.
17. Kuhse, J., Kuryatov, A., Maulet, Y., Malosio, M.-L., Schmieden, V. and Betz, H. Alternative splicing generates two isoforms of the α2 subunit of the inhibitory glycine receptor, FEBS Lett., 283 (1991) 73-77.
18. Lindstrom, J.M., Nicotinic acetylcholine receptors. In R.A. North (Ed.), Handbook of Receptors and Channels: Ligand- and Voltage-Gated Ion Channels, CRC Press, Boca Raton, FL, 1995, pp 153-175.
19. Lowry, O.H., Rosebrough, N.J., Farr, A.L. and Randall, R.J., Protein measurement with the Folin phenol reagent, J. Biol. Chem., 193 (1951) 265-275.
20. Loring, R.H., Aizenmann, E., Lipton, S.A. and Zigmond, R.E., Characterization of nicotinic receptors in chick retina using a snake venom neurotoxin that blocks neuronal nicotinic receptor function, J. Neurosci., 9 (1989) 2423-2431.
21. Malosio, M.-L., Grenningloh, G., Kuhse, J., Schmieden, V., Schmitt, B., Prior, P. and Betz, H., Alternative splicing generates two variants of the α1 subunit of the inhibitory glycine receptor, J. Biol. Chem., 266 (1991) 2048-2053.
22. Marks, M.J., Pauly, J.R., Grun, E.U. and Collins, A.C., ST/b and DBA/2 mice differ in brain α-bungarotoxin binding and α7 nicotinic receptor subunit mRNA levels: a quantitative autoradiographic analysis, Mol. Brain Res., 39 (1996) 207-222.
23. Marks, M.J., Pauly, J.R., Gross, S.D., Deneris, E.S., Hermans-Borgmeyer, I., Heinemann, S. and Collins, A.C., Nicotine binding and nicotinic receptor subunit RNA after chronic treatment, J. Neurosci., 12 (1992) 2765-2784.
24. Marks, M.J., Romm, E., Campbell, S.M. and Collins, A.C., Variation of nicotinic binding sites among inbred strains, Pharmacol. Biochem. Behav., 33 (1989) 679-689.
25. Marks, M.J., Stitzel, J.A. and Collins, A.C., Genetic influences on nicotine responses, Pharmacol. Biochem. Behav., 33 (1989) 667-678.
26. Marks, M.J., Stitzel, J.A., Romm, E., Wehner, J.M. and Collins, A.C., Nicotinic binding sites in rat and mouse brain: comparison of acetylcholine, nicotine and α-bungarotoxin, J. Pharmacol. Exp. Ther. 30 (1986) 427-436.
27. Marks, M.J., Romm, E., Bealer, S. and Collins, A.C., A test battery for measuring nicotine effects in mice, Pharmacol. Biochem. Behav., 23 (1985) 325-330.
28. Marks, M.J. and Collins, A.C., Characterization of nicotine binding in mouse brain and comparison with the binding of α-bungarotoxin and quinuclidinyl benzilate, Mol. Pharmacol., 22 (1982) 554-564.
29. Melton, D.A., Kreig, P.A., Rebagliati, M.R., Maniatis, T., Zinn, K. and Green, M.R., Efficient in vitro synthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter, Nucleic Acids Res., 12 (1984) 7035-7056.
30. Miner, L.L. and Collins, A.C., Strain comparison of nicotine-induced seizure sensitivity and nicotinic receptors, Pharmacol. Biochem. Behav., 33 (1989) 469-475.
31. Miner, L.L., Marks, M.J. and Collins, A.C., Classical genetic analysis of nicotine-induced seizures and nicotinic receptors, J. Pharmacol. Exp. Ther., 231 (1984) 545-554.
32. Miner, L.L., Marks, M.J. and Collins, A.C., Relationship between nicotine-induced seizures and hippocampal nicotinic receptors, Life Sci., 37 (1985) 75-83.
33. Miner, L.L., Marks, M.J. and Collins, A.C., Genetic analysis of nicotine-induced seizures and hippocampal nicotinic receptors in the mouse, J. Pharmacol. Exp. Ther., 239 (1986) 853-860.
34. Nagavarapu, U. and Boyd, R.T., Distribution of neuronal nicotinic acetylcholine receptor gene restriction fragment length polymorphisms in inbred and partially inbred mice, Pharmacogenetics, 5 (1995) 326-331.
35. Nakayama, H., Nakashima, T. and Kurogochi, Y., α4 is a major acetylcholine binding subunit of cholinergic ligand affinity-purified nicotinic acetylcholine receptor from rat brains, Neurosci. Lett., 121 (1991) 122-124.
36. Orr-Urtreger, A., Seldin, M.F., Baldini, A. and Beaudet, A.L., Cloning and mapping of the mouse α7-neuronal nicotinic acetlycholine receptor, Genomics, 26 (1995) 399-402.
37. 3H]Cytisine binding to nicotinic cholinergic receptors in brain, Mol. Pharmacol., 39 (1991) 9-12.
38. Pauly, J.R., Stitzel, J.A., Marks, M.J. and Collins, A.C., An autoradiographic analysis of cholinergic receptors in mouse brain, Brain Res. Bull., 22 (1989) 453-459.
39. 3H]Epibatidine labels nicotinic receptors in rat brain: an autoradiographic study, J. Pharmacol. Exp. Ther., 275 (1995) 1030-1034.
40. Rogers, S.W., Mandelzys, A., Deneris, E.S., Cooper, E. and Heinemann, S., The expression of nicotinic acetylcholine receptors by PC12 cells treated with NGF, J. Neurosci., 12 (1992) 4611-4623.
41. Romano, C. and Goldstein, A., Stereospecific nicotine receptors on rat brain membranes, Science, 210 (1980) 647-650.
42. Sambrook, J., Fritsch, E.F. and Maniatis, T. (Eds.), Molecular Cloning: A Laboratory Manual, 2nd edn., Cold Spring Harbor Laboratory Press, 1990.
43. Sanger, F., Nicklen, S. and Coulson, A.R., DNA sequencing with chain-terminating inhibitors, Proc. Natl. Acad. Sci. USA, 74 (1977) 5463-5467.
44. Schoepfer, R., Conroy, W.G., Whiting, P., Gore, M. and Lindstrom, J., Brain α-bungarotoxin binding protein cDNAs and MAbs reveal subtypes of this branch of the ligand-gated ion channel gene superfamily, Neuron, 5 (1990) 35-48.
45. 3H]acetylcholine in rat brain, Mol. Pharmacol., 22 (1982) 56-62.
46. 7: a nicotinic cation channel highly permeable to calcium, J. Neurosci., 13 (1993) 596-604.
47. Steinlein, O.K., Mulley, J.C., Propping, P., Wallace, R.H., Phillips, H.A., Sutherland, G.R., Scheffer, E.I., Berkovic, S.F., A missense mutation in the neuronal nicotinic acetlycholine receptor α4 subunit is associated with autosomal dominant nocturnal frontal lobe epilepsy, Nature Genet., 11 (1995) 201-203.
48. Stitzel, J.A., Robinson, S.F. and Collins, A.C., Differences in response to nicotine are determined by genetic factors. In P.B.S. Clarke, M. Quik, F. Adlkofer and K. Thurau (Eds.), Effects of Nicotine on Biological Systems II, Birkhäuser, Basel, 1995, pp. 279-284.
49. 5) in the rat central nervous system, Brain Res., 526 (1990) 45-53.
50. Wada, E., Wada, K., Boulter, J., Deneris, E., Heinemann, S., Patrick, J. and Swanson, L.W., Distribution of α2, α3, α4 and β2 neuronal nicotinic receptor subunit mRNAs in the central nervous system: a hybridization histochemical study in the rat, J. Comp. Neurol., 284 (1989) 314-335.
51. Wada, K., Ballivet, M., Boulter, J., Connolly, J., Wada, E., Deneris, E.S., Swanson, L.W., Heinemann, S. and Patrick, J., Functional expression of a new pharmacological subtype of brain nicotinic acetlycholine receptor, Science, 240 (1988) 330-334.