An automatable microassay for phenyl valerate esterase activities sensitive to organophosphorus compounds

Toxicology Letters

Volumn 89, Issue 3, 1996, Pages 241-247

  Escudero, M A ^a   Sogorb, M A ^a   Vilanova, E ^a  

^a UNIVERSITY OF ALICANTE   (Spain)

Author keywords

automated microassay; neuropathy target esterase; organophosphorus compounds; phenyl valerate esterase

Indexed keywords

MIPAFOX; NEUROTOXIC ESTERASE; ORGANOPHOSPHATE; PARAOXON;

ANIMAL TISSUE; ARTICLE; AUTOMATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ASSAY; HEN; NONHUMAN; PRIORITY JOURNAL; SCIATIC NERVE;

ANIMALS; AUTOMATION; BIOLOGICAL MARKERS; CARBOXYLIC ESTER HYDROLASES; FEMALE; MICROCHEMISTRY; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

EID: 0030608425     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4274(96)03821-0     Document Type: Article

References (14)

1. [1] Reiner, E., Aldridge, W.N. and Hoskin, F.C. (1989) Enzymes hydrolysing organophosphorus compounds. In: Anonymous Ellis Norwood Limited.
2. [2] Reiner, E. and Lotti, M. (1993) Special Issue: Enzymes Interacting with Organophosphorus Compounds. Chem.-Biol. Interact. 87, Nos. 1-3.
3. [3] Johnson, M.K. (1982) The target for initiation of delayed neurotoxicity by organophosphorus esters: biochemical and toxicological applications. Rev. Biochem. Toxicol. 4, 141-212.
4. [4] Johnson, M.K. (1977) Improved assay of neurotoxic esterase for screening organophosphate for delayed neurotoxicity potential. Arch. Toxicol. 37, 113-115.
5. [5] OCDE (1994). Test Guideline 418. Delayed Neurotoxicity of Substances following Acute Exposure.
6. [6] OCDE (1994) Test Gudeline 419. Delayed Neurotoxicity of Substances: 28 day Repeated One Study.
7. [7] Richardson et al. (1979) Subcellular distribution of marker enzymes and of neurotoxic esterase in adult hen brain. J. Neurochem. 32, 607-615.
8. [8] Vilanova et al. (1990) Soluble and particulate forms of the organophosphorus neuropathy target esterase in hen sciatic nerve. J. Neurochem. 55, 1258-1265.
9. [9] Carrera, V. et al. (1992) Local application of neuropathic organophosphorus compounds to hen sciatic nerve: inhibition of neuropathy target esterase and periferal neurological impairments. Toxicol. Appl. Pharmacol. 75, 350-357.
10. [10] Johnson, M.K. (1975) The delayed neuropathy caused by some organophosphorus esters: mechanism and challenge. CRC Crit. Rev. Toxicol. 3, 289-316.
11. [11] Caroldi S. and Lotti M. (1982) Neurotoxic esterase in peripheral nerve assay: inhibition and rate of resynthesis. Toxicol. Appl. Pharmacol. 62, 498 501.
12. [12] Barril, J.B. (1988) Sciatic nerve neuropathy target esterase. Methods of assay, proximodistal distribution and regeneration. Toxicology 49, 107-114.
13. [13] Lotti, M., Moretto, A., Zoppellari, R., Dainese, R., Rizzuto, N. and Barusco, G. (1986) Inhibition of lymphocitic neuropathy target esterase predicts the development of organophosphate-induced delayed polyneuropathy. Arch. Toxicol. 59, 176-179.
14. [14] Husain, K. (1994) Phenyl valerate and choline ester hydrolases in the platelets of human, hen, rat and mouse. Hum. Exp. Toxicol. 13, 157-159.