Mecamylamine-precipitated nicotine-withdrawal aversion in rats

European Journal of Pharmacology

Volumn 314, Issue 3, 1996, Pages 281-284

  Suzuki, Tsutomu ^a   Ise, Yuya ^a   Tsuda, Makoto ^a   Maeda, Jun ^a   Misawa, Miwa ^a  

^a HOSHI UNIVERSITY   (Japan)

Author keywords

Conditioned place preference paradigm; Mecamylamine; Nicotine; Physical dependence; Place aversion

Indexed keywords

MECAMYLAMINE; NICOTINE;

ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG DEPENDENCE; MALE; NONHUMAN; PLACE PREFERENCE; PRIORITY JOURNAL; RAT; SUBCUTANEOUS DRUG ADMINISTRATION;

ANALYSIS OF VARIANCE; ANIMALS; AVOIDANCE LEARNING; DRUG EVALUATION, PRECLINICAL; EVALUATION STUDIES; INJECTIONS, SUBCUTANEOUS; MALE; MECAMYLAMINE; MOTIVATION; NICOTINE; NICOTINIC AGONISTS; NICOTINIC ANTAGONISTS; RATS; RATS, SPRAGUE-DAWLEY; SUBSTANCE WITHDRAWAL SYNDROME;

EID: 0030608344     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(96)00723-6     Document Type: Article

References (15)

1. Costall, B., B.J. Jones, M.E. Kelly, R.J. Naylor, E.S. Onaivi and M.B. Tyers, 1990, Sites of action of ondansetron to inhibit withdrawal from drugs of abuse, Pharmacol. Biochem. Behav. 36, 97.
2. Di Chiara, G. and A. Imperato, 1988, Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats, Proc. Natl. Acad. Sci. USA 85, 5274.
3. Fudala, P.J., K.W. Teoh and E.T. Iwamoto, 1985, Pharmacologic characterization of nicotine-induced conditioned place preference, Pharmacol. Biochem. Behav. 22, 237.
4. Fung, Y.K., M.J. Schmid, T.M. Anderson and Y.-S. Lau, 1996, Effects of nicotine withdrawal on central dopaminergic systems, Pharmacol. Biochem. Behav. 53, 635.
5. Harris, C.M., M.W. Emmett-Oglesby, N.G. Robinson and H. Lal, 1986, Withdrawal from chronic nicotine substitutes partially for the interoceptive stimulus produced by pentylenetetrazol (PTZ), Psychopharmacology 90, 85.
6. Hoffman, D.C., 1989, The use of place conditioning in studying the neuropharmacology of drug reinforcement, Brain Res. Bull. 23, 373.
7. Hughes, J.R., S.W. Gust, K. Skoog, R.M. Keenan and J.W. Fenwick, 1991, Symptoms of tobacco withdrawal: a replication and extension, Arch. Gen. Psychiatry 48, 52.
8. Malin, D.H., J.R. Lake, V.A. Carter, J.S. Cunningham and O.B. Wilson, 1993, Naloxone precipitates nicotine abstinence syndrome in the rat, Psychopharmacology 112, 339.
9. Malin, D.H., J.R. Lake, V.A. Carter, J.S. Cunningham, K.M. Hebert, D.L. Conrad and O.B. Wilson, 1994, The nicotinic antagonist mecamylamine precipitates nicotine abstinence syndrome in the rat, Psychopharmacology 115, 180.
10. Mucha, R.F., 1987, Is the motivational effect of opiate withdrawal reflected by common somatic indices of precipitated withdrawal? A place conditioning study in the rat, Brain Res. 418, 214.
11. Mucha, R.F. and A. Herz, 1985, Motivational properties of kappa- and mu-opioid receptor agonists studied with place and taste preference conditioning procedures, Psychopharmacology 86, 274.
12. Risinger, F.O. and R.A. Oakes, 1995, Nicotine-induced conditioned place preference and conditioned place aversion in mice, Pharmacol. Biochem. Behav. 51, 457.
13. Suzuki, T., Y. Masukawa and M. Misawa, 1990, Drug interactions in the reinforcing effects of over-the-counter cough syrups, Psychopharmacology 102, 438.
14. Suzuki, T., M. Tsuji, T. Mori, M. Misawa and H. Nagase, 1995, Effect of naltrindole on the development of physical dependence on morphine in mice: a behavioral and biochemical study, Life Sci. 57, PL247.
15. Takada, K., S. Katoh and T. Yanagita, 1988, Nicotine dependence in rats, Jpn. J. Psychopharmacol. 8, 295.