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Volumn 63, Issue 2-3, 1996, Pages 123-132

Decreased serotonergic responsivity in platelets of drug-free patients with schizophrenia

Author keywords

5 Hydroxytryptamine; Dense granule secretion; Haloperidol

Indexed keywords

ADENOSINE DIPHOSPHATE; HALOPERIDOL; NEUROLEPTIC AGENT; SEROTONIN;

EID: 0030608116     PISSN: 01651781     EISSN: None     Source Type: Journal    
DOI: 10.1016/0165-1781(96)02862-4     Document Type: Article
Times cited : (29)

References (45)
  • 1
    • 0002011491 scopus 로고
    • Which test(s) for platelet aggregation?
    • Born, G.V.R. and Neri Serneri, G.G. (Eds.), Excerpta Medica, Amsterdam
    • Abbate, R. and Boddi, M. (1987) Which test(s) for platelet aggregation? In: Born, G.V.R. and Neri Serneri, G.G. (Eds.), Antiplatelet Therapy: Twenty Years' Experience. Excerpta Medica, Amsterdam, pp. 91-102.
    • (1987) Antiplatelet Therapy: Twenty Years' Experience , pp. 91-102
    • Abbate, R.1    Boddi, M.2
  • 2
    • 0019945902 scopus 로고
    • Negative symptoms in schizophrenia: Definition and reliability
    • Andreasen, N.C. (1982) Negative symptoms in schizophrenia: Definition and reliability. Arch Gen Psychiatry 39, 784-794.
    • (1982) Arch Gen Psychiatry , vol.39 , pp. 784-794
    • Andreasen, N.C.1
  • 3
    • 0028225072 scopus 로고
    • Effect of clozapine treatment on serotonin-2-receptor binding in the blood platelets of schizophrenic patients
    • Arora, R.C. and Meltzer, H.Y. (1994) Effect of clozapine treatment on serotonin-2-receptor binding in the blood platelets of schizophrenic patients. Neuropsychopharmacology 10, 109-114.
    • (1994) Neuropsychopharmacology , vol.10 , pp. 109-114
    • Arora, R.C.1    Meltzer, H.Y.2
  • 5
    • 0020538735 scopus 로고
    • Effects of ketanserin and mepyramine on platelet aggregation and on the uptake of 5-hydroxytryptamine into platelets
    • Bevan, J. and Heptinstall, S. (1983) Effects of ketanserin and mepyramine on platelet aggregation and on the uptake of 5-hydroxytryptamine into platelets. Thromb Res 30, 415-423.
    • (1983) Thromb Res , vol.30 , pp. 415-423
    • Bevan, J.1    Heptinstall, S.2
  • 6
    • 0015930585 scopus 로고
    • 5-hydroxyindole acetic acid (5-HIAA) and homovanillic acid (HVA) following protencid in acute psychiatric patients treated with phenothiazines
    • Bowers, M.B. (1973) 5-Hydroxyindole acetic acid (5-HIAA) and homovanillic acid (HVA) following protencid in acute psychiatric patients treated with phenothiazines. Psychopharmacology 28, 309-318.
    • (1973) Psychopharmacology , vol.28 , pp. 309-318
    • Bowers, M.B.1
  • 7
    • 0001236176 scopus 로고
    • Methods for reliable longitudinal observation of behavior
    • Bunney, W.E. and Hamburg, D.A. (1963) Methods for reliable longitudinal observation of behavior. Arch Gen Psychiatry 19, 280-294.
    • (1963) Arch Gen Psychiatry , vol.19 , pp. 280-294
    • Bunney, W.E.1    Hamburg, D.A.2
  • 8
    • 0025563074 scopus 로고
    • The role of serotonin in thrombogenesis
    • De Clerck, F. (1990) The role of serotonin in thrombogenesis. Clin Physiol Biochem 8 (Suppl. 3), 40-49.
    • (1990) Clin Physiol Biochem , vol.8 , Issue.SUPPL. 3 , pp. 40-49
    • De Clerck, F.1
  • 10
    • 0019510058 scopus 로고
    • Increased whole blood serotonin concentrations in chronic schizophrenic patients
    • DeLisi, L.E., Neckers, L.M., Weinberger, D.R. and Wyatt, R. (1981) Increased whole blood serotonin concentrations in chronic schizophrenic patients. Arch Gen Psychiatry 38, 647-650.
    • (1981) Arch Gen Psychiatry , vol.38 , pp. 647-650
    • Delisi, L.E.1    Neckers, L.M.2    Weinberger, D.R.3    Wyatt, R.4
  • 11
    • 0016304812 scopus 로고
    • Free and bound serum tryptophan in drug-free normal controls and chronic schizophrenic patients
    • Domino, E.F. and Krause, R.R. (1974) Free and bound serum tryptophan in drug-free normal controls and chronic schizophrenic patients. Biol Psychiatry 8, 265-279.
    • (1974) Biol Psychiatry , vol.8 , pp. 265-279
    • Domino, E.F.1    Krause, R.R.2
  • 12
    • 0024244890 scopus 로고
    • Sensitive electrochemical high-performance liquid chromatography assay for the simultaneous determination of haloperidol and reduced haloperidol
    • Eddington, N.D. and Young, D. (1988) Sensitive electrochemical high-performance liquid chromatography assay for the simultaneous determination of haloperidol and reduced haloperidol. J Pharmacol Sci 77, 541-543.
    • (1988) J Pharmacol Sci , vol.77 , pp. 541-543
    • Eddington, N.D.1    Young, D.2
  • 13
    • 0018119373 scopus 로고
    • A diagnostic interview: The Schedule for Affective Disorders and Schizophrenia
    • Endicott, J. and Spitzer, R.L. (1978) A diagnostic interview: the Schedule for Affective Disorders and Schizophrenia. Arch Gen Psychiatry 35, 837-844.
    • (1978) Arch Gen Psychiatry , vol.35 , pp. 837-844
    • Endicott, J.1    Spitzer, R.L.2
  • 14
    • 0025088414 scopus 로고
    • The platelet polyphosphoinositide system in schizophrenia: The effect of neuroleptic treatment
    • Essali, M.A., Das, I., de Belleroche, J. and Hirsch, S.R. (1990) The platelet polyphosphoinositide system in schizophrenia: The effect of neuroleptic treatment. Biol Psychiatry 28, 475-487.
    • (1990) Biol Psychiatry , vol.28 , pp. 475-487
    • Essali, M.A.1    Das, I.2    De Belleroche, J.3    Hirsch, S.R.4
  • 16
    • 0016670454 scopus 로고
    • Elevated blood serotonin concentration in unmedicated chronic schizophrenic patients
    • Garelis, E., Gillin, J.C., Wyatt, R. and Neff, N. (1975) Elevated blood serotonin concentration in unmedicated chronic schizophrenic patients. Am J Psychiatry 132, 184-186.
    • (1975) Am J Psychiatry , vol.132 , pp. 184-186
    • Garelis, E.1    Gillin, J.C.2    Wyatt, R.3    Neff, N.4
  • 17
    • 0017142402 scopus 로고
    • Clinical effects of tryptophan in chronic schizophrenic patients
    • Gillin, J.C., Kaplan, J.A. and Wyatt, R.J. (1976) Clinical effects of tryptophan in chronic schizophrenic patients. Biol Psychiatry 11, 635-639.
    • (1976) Biol Psychiatry , vol.11 , pp. 635-639
    • Gillin, J.C.1    Kaplan, J.A.2    Wyatt, R.J.3
  • 19
    • 0020563171 scopus 로고
    • Platelet serotonin levels in schizophrenia: Relationship to race and psychopathology
    • Jackman, H., Luchins, D. and Meltzer, H.Y. (1983) Platelet serotonin levels in schizophrenia: Relationship to race and psychopathology. Biol Psychiatry 18, 887-902.
    • (1983) Biol Psychiatry , vol.18 , pp. 887-902
    • Jackman, H.1    Luchins, D.2    Meltzer, H.Y.3
  • 20
    • 0017755438 scopus 로고
    • Platelet serotonin concentration and monoamine oxidase activity in unmedicated chronic schizophrenic and schizoaffective patients
    • Joseph, M., Owen, F., Baker, H. and Bourne, R. (1977) Platelet serotonin concentration and monoamine oxidase activity in unmedicated chronic schizophrenic and schizoaffective patients. Psychol Med 7, 159-162.
    • (1977) Psychol Med , vol.7 , pp. 159-162
    • Joseph, M.1    Owen, F.2    Baker, H.3    Bourne, R.4
  • 21
    • 0024473920 scopus 로고
    • Accumulation of diacylglycerol in platelet phosphoinositide turnover in schizophrenia: A biological marker of good prognosis?
    • Kaiya, H., Nishida, A., Imai, A., Nakashima, S.N. and Nozawa, Y. (1989) Accumulation of diacylglycerol in platelet phosphoinositide turnover in schizophrenia: A biological marker of good prognosis? Biol Psychiatry 26, 669-676.
    • (1989) Biol Psychiatry , vol.26 , pp. 669-676
    • Kaiya, H.1    Nishida, A.2    Imai, A.3    Nakashima, S.N.4    Nozawa, Y.5
  • 22
    • 0023128001 scopus 로고
    • Platelet serotonin concentration in schizophrenic patients
    • Kolakowska, T. and Molyneux, S.G. (1987) Platelet serotonin concentration in schizophrenic patients. Am J Psychiatry 144, 232-234.
    • (1987) Am J Psychiatry , vol.144 , pp. 232-234
    • Kolakowska, T.1    Molyneux, S.G.2
  • 23
    • 0018760877 scopus 로고
    • The effects of dopaminergic blocking agents on the glucose tolerance level in 6 humans and 6 dogs
    • Lechin, F., Coll-Garcia, F., Vander Dija, A., Bentolila, A., Pena, F. and Rivar, C. (1979) The effects of dopaminergic blocking agents on the glucose tolerance level in 6 humans and 6 dogs. Experientia 35, 886-887.
    • (1979) Experientia , vol.35 , pp. 886-887
    • Lechin, F.1    Coll-Garcia, F.2    Vander Dija, A.3    Bentolila, A.4    Pena, F.5    Rivar, C.6
  • 24
    • 0027212698 scopus 로고
    • Primary structure of the human platelet serotonin uptake site: Identity with the brain serotonin transporter
    • Lesch, K.-P., Wolozin, D.L., Murphy, D.L. and Riederer, P. (1993) Primary structure of the human platelet serotonin uptake site: Identity with the brain serotonin transporter. J Neurochem 60, 2319-2322.
    • (1993) J Neurochem , vol.60 , pp. 2319-2322
    • Lesch, K.-P.1    Wolozin, D.L.2    Murphy, D.L.3    Riederer, P.4
  • 26
    • 0015610177 scopus 로고
    • Low plasma tryptophan levels in recently hospitalized schizophrenics
    • Manowitz, P., Gilmour, D.G. and Racevskis, J. (1973) Low plasma tryptophan levels in recently hospitalized schizophrenics. Biol Psychiatry 6, 109-118.
    • (1973) Biol Psychiatry , vol.6 , pp. 109-118
    • Manowitz, P.1    Gilmour, D.G.2    Racevskis, J.3
  • 28
    • 0024468417 scopus 로고
    • Clinical studies on the mechanism of action of clozapine: The dopamine-serotonin hypothesis of schizophrenia
    • Meltzer, H.Y. (1989) Clinical studies on the mechanism of action of clozapine: The dopamine-serotonin hypothesis of schizophrenia. Psychopharmacology 99, S18-S27.
    • (1989) Psychopharmacology , vol.99
    • Meltzer, H.Y.1
  • 29
    • 0026091799 scopus 로고
    • The mechanism of action of novel antipsychotic drugs
    • Meltzer, H.Y. (1991) The mechanism of action of novel antipsychotic drugs. Schizophr Bull 17, 263-287.
    • (1991) Schizophr Bull , vol.17 , pp. 263-287
    • Meltzer, H.Y.1
  • 30
    • 0023856580 scopus 로고
    • Time course of schizophrenia and platelet 5-HT level
    • Muck-Seler, D., Jakovljevie, M. and Deanovie, Z. (1988) Time course of schizophrenia and platelet 5-HT level. Biol Psychiatry 23, 243-251.
    • (1988) Biol Psychiatry , vol.23 , pp. 243-251
    • Muck-Seler, D.1    Jakovljevie, M.2    Deanovie, Z.3
  • 31
    • 0022531795 scopus 로고
    • Differential effects of chlorpromazine on secretion, protein phosphorylation and phosphoinositide metabolism in stimulated platelets
    • Opstvedt, A., Rongved, S., Arasaether, N., Lillenhaug, R. and Holmsen, H. (1986) Differential effects of chlorpromazine on secretion, protein phosphorylation and phosphoinositide metabolism in stimulated platelets. Biochem J 238, 159-166.
    • (1986) Biochem J , vol.238 , pp. 159-166
    • Opstvedt, A.1    Rongved, S.2    Arasaether, N.3    Lillenhaug, R.4    Holmsen, H.5
  • 32
    • 0027177906 scopus 로고
    • 2 receptor binding characteristics in the individual and the putative regulation by serotonin
    • 2 receptor binding characteristics in the individual and the putative regulation by serotonin. J Neural Transm 93, 27-35.
    • (1993) J Neural Transm , vol.93 , pp. 27-35
    • Ostrowitzki, S.1    Rao, M.L.2    Redei, J.3    Andres, A.H.4
  • 33
    • 0000503515 scopus 로고
    • The Brief Psychiatric Rating Scale
    • Overall, J.E. and Gorham, D.R. (1962) The Brief Psychiatric Rating Scale. Psychol Rep 10, 799-812.
    • (1962) Psychol Rep , vol.10 , pp. 799-812
    • Overall, J.E.1    Gorham, D.R.2
  • 34
    • 0022650427 scopus 로고
    • Critical evaluation of platelet aggregation in whole human blood
    • Riess, H., Braun, G., Brehm, G. and Hiller, E. (1986) Critical evaluation of platelet aggregation in whole human blood. Am J Clin Pathol 85, 50-56.
    • (1986) Am J Clin Pathol , vol.85 , pp. 50-56
    • Riess, H.1    Braun, G.2    Brehm, G.3    Hiller, E.4
  • 35
    • 0026533935 scopus 로고
    • 2-adrenergic receptor populations on phosphoinositide hydrolysis
    • 2-adrenergic receptor populations on phosphoinositide hydrolysis. Life Sci 50, 169-180.
    • (1991) Life Sci , vol.50 , pp. 169-180
    • Rigatti, B.W.1    Paleos, G.A.2    Mann, J.J.3
  • 36
    • 0023820738 scopus 로고
    • Detection of small inhibitory effects of acetylsalicylic acid (ASA) by platelet impedance aggregometry in whole blood
    • Sathiropas, P., Marbet, G.A., Sahaphong, S. and Duckert, F. (1988) Detection of small inhibitory effects of acetylsalicylic acid (ASA) by platelet impedance aggregometry in whole blood. Thromb Res 51, 55-62.
    • (1988) Thromb Res , vol.51 , pp. 55-62
    • Sathiropas, P.1    Marbet, G.A.2    Sahaphong, S.3    Duckert, F.4
  • 38
    • 0020675866 scopus 로고
    • Hyperserotoninemia and platelet serotonin uptake and release in schizophrenia and affective disorders
    • Stahl, S.M., Wood, D.J., Mefford, I.N., Berger, P.A. and Ciaranello, R.D. (1983) Hyperserotoninemia and platelet serotonin uptake and release in schizophrenia and affective disorders. Am J Psychiatry 140, 26-30.
    • (1983) Am J Psychiatry , vol.140 , pp. 26-30
    • Stahl, S.M.1    Wood, D.J.2    Mefford, I.N.3    Berger, P.A.4    Ciaranello, R.D.5
  • 41
    • 0015520159 scopus 로고
    • Behavioral changes of chronic schizophrenic patients given L-5-hydroxytryptophan
    • Wyatt, R.J., Vaughan, T., Galanter, M., Kaplan, J. and Green, R. (1972) Behavioral changes of chronic schizophrenic patients given L-5-hydroxytryptophan. Science 177, 1124-1126.
    • (1972) Science , vol.177 , pp. 1124-1126
    • Wyatt, R.J.1    Vaughan, T.2    Galanter, M.3    Kaplan, J.4    Green, R.5
  • 42
    • 0028084803 scopus 로고
    • Red blood cell membrane dynamics schizophrenia. I. Membrane fluidity
    • Yao, J.K. and van Kammen, D.P. (1994) Red blood cell membrane dynamics schizophrenia. I. Membrane fluidity. Schizophr Res 11, 209-216.
    • (1994) Schizophr Res , vol.11 , pp. 209-216
    • Yao, J.K.1    Van Kammen, D.P.2
  • 43
    • 0027978178 scopus 로고
    • Red blood cell membrane dynamics in schizophrenia. III. Correlation of fatty acid abnormalities with clinical measures
    • Yao, J.K., van Kammen, D.P. and Gurklis, J. (1994a) Red blood cell membrane dynamics in schizophrenia. III. Correlation of fatty acid abnormalities with clinical measures. Schizophr Res 13, 227-232.
    • (1994) Schizophr Res , vol.13 , pp. 227-232
    • Yao, J.K.1    Van Kammen, D.P.A.2    Gurklis, J.3
  • 44
    • 0028080258 scopus 로고
    • Platelet aggregation and dense granule secretion in schizophrenia
    • Yao, J.K., van Kammen, D.P., Gurklis, J. and Peters, J.L. (1994b) Platelet aggregation and dense granule secretion in schizophrenia. Psychiatry Res 54, 13-24.
    • (1994) Psychiatry Res , vol.54 , pp. 13-24
    • Yao, J.K.1    Van Kammen, D.P.2    Gurklis, J.3    Peters, J.L.4


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