Motor depressant effects of systemically administered polyamines in mice: Involvement of central NMDA receptors

European Journal of Pharmacology

Volumn 318, Issue 2-3, 1996, Pages 231-238

  Giménez Llort, Lidia ^a   Ferré, Sergi ^a   De Vera, Núria ^a   Martínez, Emili ^a  

^a CSIC   (Spain)

Author keywords

Amphetamine; MK 801; Motor activity; Mouse; NMDA (N methyl D aspartate); Polyamine; Putrescine; Spermidine; Spermine; Theophylline

Indexed keywords

ADENOSINE RECEPTOR BLOCKING AGENT; AMPHETAMINE; DIZOCILPINE; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; POLYAMINE; PUTRESCINE; SPERMIDINE; SPERMINE; THEOPHYLLINE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG BRAIN LEVEL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; MOTOR ACTIVITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; SUBCUTANEOUS DRUG ADMINISTRATION;

AMPHETAMINE; ANIMALS; BIOGENIC POLYAMINES; BRAIN; BRAIN CHEMISTRY; DIZOCILPINE MALEATE; MALE; MICE; MOTOR ACTIVITY; N-METHYLASPARTATE; RECEPTORS, N-METHYL-D-ASPARTATE; THEOPHYLLINE;

EID: 0030607668     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(96)00786-8     Document Type: Article

References (37)

1. 1 dopamine receptors reveals direct effects of preferential dopamine autoreceptor agonist B-HT 920 on postsynaptic dopamine receptors, Acta Physiol. Scand. 134, 285.
2. Camon, L., N. De Vera and E. Martínez, 1994, On the neurotoxicity of systemically administered putrescine: influence of kinetic factors, Neurotoxicology 15, 759.
3. Chu, P., A. Shirahata, K. Samejima, H. Saito and K. Abe, 1994, N-(3-Aminopropyl)-cyclohexylamine blocs facilitation by spermidine of N-methyl-DL-aspartate-induced seizure in mice in vivo, Eur. J. Pharmacol. 256, 155.
4. Carter, C., 1994, The Neuropharmacology of Polyamines (Academic Press, London).
5. Crawley, J.N., J.R. Evers and S.M. Pau, 1992, Polyamines inhibit NMDA antagonist-induced darting behavior in the rat prefrontal cortex, Brain Res. 586, 6.
6. De Vera, N., J. Serratosa, F. Artigas and E. Martínez, 1992, Polyamines can mediate the action of excitotoxins. Toxic effects of putrescine in the rat, Amino Acids 3, 261.
7. Ferré, S., K. Fuxe, G. Von Euler, B. Johansson and B.B. Fredholm, 1992, Adenosine-dopamine interactions in the brain, Neuroscience 51, 501.
8. 2 receptors, Eur. J. Pharmacol. 255, 203.
9. 1 receptors, NeuroReport 6, 73.
10. Giménez-Llort, L., S. Ferré and E. Martínez, 1995a, Effects of the systemic administration of kainic acid and NMDA on exploratory activity in rats, Pharmacol. Biochem. Behav. 51, 205.
11. Giménez-Llort, L., E. Martínez and S. Ferré, 1995b, Dopamine-independent and adenosine-dependent mechanisms involved in the effects of NMDA on motor activity in mice, Eur. J. Pharmacol. 275, 171.
12. Hirsch, S.R., R. Richardson-Andrews, B. Costall, M.E. Kelly, J. De Belleroche and R.J. Naylor, 1987, The effects of some polyamines on the putative behavioural indices of mesolimbic versus striatal dopaminergic function, Psychopharmacology 93, 101.
13. Hollmann, M. and S. Hienemann, 1994, Cloned glutamate receptors, Annu. Rev. Neurosci. 17, 31.
14. Irifune, M., T. Shimizu, M. Nomoto and T. Fukuda, 1995, Involvement of N-methyl-D-aspartate (NMDA) receptors in noncompetitive NMDA receptor antagonist-induced hyperlocomotion in mice, Pharmacol. Biochem. Behav. 51, 291.
15. Lodge, D. and G. Collingridge, 1990, TIPS Reviews: Pharmacology of Excitatory Amino Acids (Elsevier, London).
16. London, E.D., V.L. Dawson and C.R. Mantione, 1991, Specific binding sites for polyamines in mammalian brain, in: NMDA Receptor Related Agents: Biochemistry, Pharmacology and Behavior, eds. T. Kameyama, T. Nabeshima and E.F. Domino (NPP Books, Ann Arbor, MI).
17. Martínez, E., N. De Vera and F. Artigas, 1991, Differential response of rat brain polyamines to convulsant agents, Life Sci. 48, 77.
18. 3H]Dizocilpine association kinetics distinguish stimulatory and inhibitory polyamine sites of NMDA receptors, J. Neurochem. 63, 963.
19. Monagham, D.T., R.J. Bridges and C.W. Cotman, 1989, The excitatory amino acid receptors: their classes, pharmacology and distinct properties in the function of the central nervous system, Annu. Rev. Pharmacol. 29, 365.
20. Moriyoshi, K., M. Masayuki, T. Ishii, R. Shigemoto, N. Mizuno and S. Nakanishi, 1991, Molecular cloning and characterization of the rat NMDA receptor, Nature 354, 31.
21. Munir, M., S. Subramaniam and P. McGonigle, 1993, Polyamines modulate the neurotoxic effects of NMDA in vivo, Brain Res. 616, 163.
22. Paschen, W., 1992. Polyamine metabolism in different pathological states of the brain, Mol. Chem. Neuropathol. 16, 241.
23. + depolarization, tetrodotoxin and NMDA receptor inhibition on extracellular adenosine levels in rat striatum, Eur. J. Pharmacol. 234, 61.
24. Pazzagli, M., C. Corsi, S. Latini, F. Pedata and G. Pepeu, 1994, In vivo regulation of extracellular levels in the cerebral cortex by NMDA and muscarinic receptors, Eur. J. Pharmacol. 254, 277.
25. 3H]MK-801 binding to the N-methyl-D-aspartate receptor-ion channel complex with L-glutamate, glycine and polyamines, J. Neurochem. 51, 830.
26. Rock, D.M. and R.L. Macdonald, 1995, Polyamine regulation of NMDA receptor channels, Annu. Rev. Pharmacol. Toxicol. 35, 463.
27. 3H]N-(1-[thienyl]cyclohexyl)piperidine binding to the NMDA receptor ionophore complex, Mol. Pharmacol. 37, 572.
28. Sakurada, T., K. Onodera; T. Tadano and K. Kisara, 1983, Effects of polyamines on the central nervous system, Jpn. J. Pharmacol. 25, 653.
29. Seiler, N., 1991, Pharmacological properties of the natural polyamines and their depletion by biosynthesis inhibitors as a therapeutic approach, Prog. Drug Res. 37, 107.
30. Shin, W.W., W.F. Fong, S.F. Pang and P.C.L. Wong, 1985, Limited blood-brain transport of polyamines, J. Neurochem. 44, 1056.
31. Singh, L., R. Oles and G. Woodruff, 1990, In vivo interaction of a polyamine with the NMDA receptor, Eur. J. Pharmacol. 180, 391.
32. 2 dopamine agonist in reserpine-treated mice, Psychopharmacology 114, 469.
33. Svensson, A., M.L. Carlsson and A. Carlsson, 1994, Glutamatergic neurons projecting to the nucleus accumbens can affect motor functions in opposite directions depending on the dopaminergic tone, Prog. Neuropsychopharmacol. Biol. Psychiatry 18, 1203.
34. Teradaira, R., K. Fujita and H. Takahashi, 1983, Acute toxicity of putrescine in rats, Pharmacometrics 25, 489.
35. 1 adenosine receptor function in rat brain by the polyamine, spermine, Neurosci. Lett. 124, 183.
36. Westbrook, G.L., 1994, Glutamate receptor update, Curr. Opin. Neurobiol. 4, 337.
37. 3H]MK-801 to the NMDA receptor: pharmacological evidence for the existence of a polyamine recognition site, Mol. Pharmacol. 36, 575.