Suplatast tosilate, a new type of antiallergic agent, prevents the expression of airway hyperresponsiveness in guinea pigs

European Journal of Pharmacology

Volumn 318, Issue 2-3, 1996, Pages 447-454

  Taniguchi, Hajime ^a   Togawa, Michinori ^a   Ohwada, Katsuo ^a   Kiniwa, Mamoru ^a   Matsuura, Naosuke ^a   Nagai, Hiroichi ^b   Koda, Akihide ^b  

^a TAIHO PHARMACEUTICAL CO LTD   (Japan)

^b GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Airway hyperresponsiveness; Airway inflammation; Eosinophil; Lymphocyte; Suplatast tosilate; T cell

Indexed keywords

ANTIALLERGIC AGENT; CD4 ANTIGEN; KETOTIFEN; SUPLATAST TOSYLATE;

ALLERGIC REACTION; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRONCHOSPASM; CONTROLLED STUDY; EOSINOPHIL; GUINEA PIG; HYPERSENSITIVITY REACTION; INFLAMMATION; INFLAMMATORY CELL; LUNG INFILTRATE; LUNG LAVAGE; LYMPHOCYTIC INFILTRATION; MACROPHAGE; MALE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; SENSITIZATION; T LYMPHOCYTE;

ANIMALS; ANTI-ALLERGIC AGENTS; ARYLSULFONATES; BRONCHIAL HYPERREACTIVITY; CD4-POSITIVE T-LYMPHOCYTES; EOSINOPHILS; GUINEA PIGS; INTERLEUKIN-5; KETOTIFEN; MALE; SULFONIUM COMPOUNDS;

EID: 0030607666     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(96)00810-2     Document Type: Article

References (21)

1. 4 and to methacholine in patients with asthma and normal controls, New Engl. J. Med. 315, 480.
2. 2 receptor antagonist, S-1452, on antigen-induced sustained bronchial hyperresponsiveness, Eur. J. Pharmacol. 260, 201.
3. Azzawi, M., B. Bradley, P.K. Jeffrey, A.J. Frew, A.J. Wardlaw, G. Knowles, B. Assouf, J.V. Collines, S. Durham and A.B. Kay, 1990, Identification of activated T lymphocytes and eosinophils in bronchial biopsies in stable atopic asthmatics, Am. Rev. Respir. Dis. 142, 1407.
4. Capron, M., 1992, Dual function of eosinophils in pathogenesis and protective immunity against parasites, Mem. Inst. Oswaldo Cruz 87 (Suppl. 5), 83.
5. Charlesworth, E.N., A. Kagey-Sobotka, P.S. Norman, L.M. Lichtenstein and H.A. Sampson, 1993, Cutaneous late-phase in food-allergic children and adolescents with atopic dermatitis, Clin. Exp. Allergy 23, 391.
6. Elwood, W., J.O. Lotvall, P.J. Barnes and K.F. Chung, 1992, Effects of dexamethasone and cyclosporin A on allergen-induced airway hyperresponsiveness and inflammatory cell responses in sensitized Brown-Norway rats. Am. Rev. Respir. Dis. 145, 1289.
7. Fink, A., H. Bibi, A. Eliraz, M. Schlesinger and Z. Bentwich, 1986, Ketotifen, disodium cromoglycate and verapamil inhibit leukotriene activity: determination by tube leukocyte adherence inhibition assay, Ann. Allergy 57, 103.
8. Fukuda, T., I. Akutsu, S. Motojima and S. Makino, 1991, Inhibition of antigen-induced late asthmatic response and bronchial hyperresponsiveness by cyclosporin and FK 506, Int. Arch. Allergy Appl. Immunol. 94, 259.
9. Iijima, H., M. Ishii, K. Yamauchi, C.-L. Chao, K. Kimura, S. Shimura, Y. Shindoh, H. Inoue, S. Mue and T. Takishima, 1987, Bronchoalveolar lavage and histologic characterization of late asthmatic response in guinea pigs, Am. Rev. Respir. Dis. 136, 922.
10. Konno, S., M. Adachi, K. Asano, Y. Gonogami, K. Ikeda, K. Okamoto and T. Takahashi, 1994, Suppressive effects of IPD-1151T (suplatast-tosilate) on induction of mast cells from normal mouse splenocytes, Eur. J. Pharmacol. 259, 15.
11. Matsuura, N., H. Mori, H. Nagai and A. Koda, 1992, Effects of suplatast tosilate (IPD-1151T) on antibody formation in mice, Folia Pharmacol. Jpn. 100, 485.
12. Mazzoni, L., J. Morley, C.P. Page and S. Sanjar, 1985, Prophylactic anti-asthma drugs impair the airway hyper-reactivity that follows exposure to platelet activating factor (PAF), Br. J. Pharmacol. 86 (Suppl.), 571P.
13. Van Oosterhout, A.J.M., A.R.C. Ladenius, H.F.J. Savelkoul, I. Van Ark, K.C. Delsman and P.P. Nijkamp, 1993, Effect of anti-IL-5 and IL-5 on airway hyperreactivity and eosinophils in guinea pigs, Am. Rev. Respir. Dis. 147, 548.
14. Robinson, D.S., S. Ying, A.M. Bentley, Q. Meng, J. North, S.R. Durham, A.B. Kay and Q. Hamid, 1993, Relationships among numbers of bronchoalveolar lavage cells expressing messenger ribonucleic acid for cytokines, asthma symptoms, and airway methacholine responsiveness in atopic asthma, J. Allergy Clin. Immunol. 92, 397.
15. Saito, H., K. Hatake, A.M. Dvorak, K.M. Leiferman, A.D. Donnenberg, N. Arai, K. Ishizaka and T. Ishizaka, 1988, Selective differentiation and proliferation of hematopoietic cells induced by recombinant human interleukins, Proc. Natl. Acad. Sci. USA 85, 2288.
16. Sanderson, C.J., D.J. Warren and M. Strath, 1985, Identification of a lymphokine that stimulates eosinophil differentiation in vitro. Its relationship to interleukin 3 and functional properties of eosinophils produced in cultures, J. Exp. Med. 162, 60.
17. Steerenberg, P.A., E. Geerse, W.H. De Jang, R. Burger, R.J. Scheper and W. Den Otter, 1991, Tumour rejection after adoptive transfer of line-10-immune spleen cells is mediated by two T cell subpopulations, Cancer Immunol. Immunother. 34, 103.
18. Thornill, M. H., U. Kyan-Aung and D. Haskard, 1990, IL-4 increases human endothelial cell adhesiveness for T cells but not for neutrophils, J. Immunol. 144, 3060.
19. Yamaguchi, Y., Y. Hayashi, Y. Sugama, Y. Miura, T. Kasahara, S. Kitamura, M. Torisu, S. Mita, A. Tominaga, K. Takatsu and T. Suda, 1988, Highly purified murine interleukin 5 (IL-5) stimulates eosinophil function and prolong in vitro survival: IL-5 as an eosinophil chemotactic factor, J. Exp. Med. 167, 1737.
20. Yamaya, H., Y. Basaki, M. Togawa, M. Kojima, M. Kiniwa and N. Matsuura, 1995, Down-regulation of Th2 cell-mediated murine peritoneal eosinophilia by antiallergic agents, Life Sci. 56, 1647.
21. Yanagihara, Y., M. Kiniwa, K. Ikizawa, T. Sida, N. Matsuura and A. Koda, 1993, Suppression of IgE production by IPD-115IT (suplatast tosilate), a new dimethylsulfonium agent: (2) Regulation of human IgE response. Jpn. J. Pharmacol. 61, 31.