Effects of Ro 47-0203 and PD155080 on the plasma kinetics, receptor binding and vascular effects of endothelin in the pig

European Journal of Pharmacology

Volumn 318, Issue 2-3, 1996, Pages 369-376

  Hemsén, Anette ^a   Modin, Agnes ^a   Wanecek, Michael ^b   Malmström, Rickard E ^a   Weitzberg, Eddie ^b  

^a KAROLINSKA INSTITUTE   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Bosentan; Clearance; Endothelin receptor antagonist; Endothelin 1; Half life; PD155080; Vascular effect

Indexed keywords

3 BENZYL 4 (4 METHOXYPHENYL) 2 (3,4 METHYLENEDIOXYPHENYL) 4 OXO 2 BUTENOIC ACID; BOSENTAN; ENDOTHELIN 1; ENDOTHELIN RECEPTOR; ENDOTHELIN RECEPTOR ANTAGONIST; RECEPTOR SUBTYPE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD LEVEL; CONDUCTANCE; CONTROLLED STUDY; FEMALE; IMMUNOREACTIVITY; INTRAVENOUS DRUG ADMINISTRATION; KIDNEY; LUNG; MALE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; SPLEEN; SWINE; VASOCONSTRICTION;

ANIMALS; DIOXOLES; ENDOTHELINS; FEMALE; HALF-LIFE; MALE; RECEPTOR, ENDOTHELIN A; RECEPTOR, ENDOTHELIN B; RECEPTORS, ENDOTHELIN; SULFONAMIDES; SWINE; VASOCONSTRICTION;

EID: 0030607654     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(96)00807-2     Document Type: Article

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