Heck reaction on solid support: Synthesis of indole analogs

Tetrahedron Letters

Volumn 37, Issue 40, 1996, Pages 7189-7192

  Yun, Weiya ^a   Mohan, Raju ^a  

^a BAYER AG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

INDOLE DERIVATIVE;

ARTICLE; DRUG SYNTHESIS; REACTION ANALYSIS;

EID: 0030607199     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/0040-4039(96)01635-8     Document Type: Article

References (13)

1. 1. Bunin, B. A. and Ellman, J. A. J. Am. Chem. Soc. 1992, 114, 10997.
2. 2. Recent reviews: a) Fruchtel, J. S. and Jung, G. Angew. Chem. Int. Ed. Engl. 1996, 35, 17;
3. b) Thompson, L. A. and Ellman, J. A. Chem. Rev. 1996, 96, 555.
4. 3. a) Heck, R. F. Org. React. 1982, 27, 345;
5. b) Heck, R. F. In Comprehensive Organic Synthesis; Trost, B. M. and Feming, I., Eds.; Pergamon Press: Oxford, New York, 1991; Vol 4, pp 833;
6. c) Larock, R. C. and Babu, S. Tetrahedron Lett. 1987, 28, 5291.
7. 4. a) Hiroshige, M.; Hauske, J. R. and Zhou, P. Tetrahedron Lett. 1995, 36, 4567;
8. b) Yu, K.-L.; Deshpande, M. S. and Vyas, D. M. Tetrahedron Lett. 1994, 55, 8919.
9. 5. a) Goff, D. A. and Zuckermann, R. N. J. Org. Chem. 1995, 60, 5748;
10. b) Hiroshige, M.; Hauske, J. R. and Zhou P. J. Am. Chem. Soc. 1995, 117, 11590.
11. 6. Wright, P.; Lioyd, D.; Rapp, W. and Andrus, A. Tetrahedron Lett. 1993, 34, 3373.
12. 2, 10-30% EtOAc-hexane gradient elution).
13. 2 m/z 251.0946, found 251.0941.