High frequency stimulation of the internal Globus Pallidus (GPi) simultaneously improves parkinsonian symptoms and reduces the firing frequency of GPi neurons in the MPTP-treated monkey

Neuroscience Letters

Volumn 215, Issue 1, 1996, Pages 17-20

  Boraud, Thomas ^a   Bezard, Erwan ^a   Bioulac, Bernard ^a   Gross, Christian ^a  

^a CNRS   (France)

Author keywords

Extracellular unit recordings of GPi; GPi high frequency stimulation; Improvement of motor symptoms; MPTP treated monkeys; Regularization of the firing frequency of GPi neurons

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ELECTROPHYSIOLOGY; ELECTROSTIMULATION; GLOBUS PALLIDUS; MONKEY; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL;

EID: 0030606831     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(96)12943-8     Document Type: Article

References (19)

1. Alexander G.E., Crutcher M.D. Functional architecture of basal ganglia circuits: neural substrates of parallel processing. Trends Neurosci. 13:1990;266-271.
2. Benabid A.L., Pollak P., Gervason C. Long-term suppression of tremor by chronic stimulation of the ventral intermediate thalamic nucleus. Lancet. 33:1991;403-406.
3. Benazzouz A., Féger J., Bioulac B., Boraud T., Gross Ch. Reversal of rigidity and improvement of motor performance by subthalamic high-frequency stimulation in MPTP-treated monkeys. Eur. J. Neurosci. 5:1993;382-389.
4. Benazzouz A., Piallat B., Pollak P., Benabid A.L. Responses of substantia nigra pars reticulata and globus pallidus complex to high frequency stimulation of the subthalamic nucleus in rats: electrophysiological data. Neurosci. Lett. 189:1995;77-80.
5. Burbaud P., Gross C., Bioulac B. Effect of subthalamic high frequency stimulation on substantia nigra pars reticulata and globus pallidus neurons in normal rats. Physiology. 88:1994;3-4.
6. Capparos-Lefebvre D., Ruchoux M.M., Blond S., Petit H., Percheron G. Long-term thalamic stimulation in Parkinson's disease. Neurology. 44:1994;1856-1860.
7. DeLong M.R. Primate model of movement disorders of basal ganglia origin. Trends Neurosci. 13:1990;281-285.
8. Deniau J.M., Chevalier G. Disinhibition as a basic process in the expression of striatal functions. II. The striato-nigral influence on thalamo-cortical cells of the ventromedial thalamic nucleus. Brain Res. 334:1985;227-233.
9. Dogali M., Fazzini E., Kolodny E., Eidelberg D., Sterio D., Devinsky O., Beric A. Stereotactic ventral pallidotomy for Parkinson's disease. Neurology. 45:1995;753-761.
10. Filion M., Tremblay L. Abnormal spontaneous activity of globus pallidus neurons in monkeys with MPTP-induced parkinsonism. Brain Res. 547:1991;142-151.
11. Gross C., Rougier A., Boraud T., Julien J. Alleviation of motor sign of Parkinson's disease after stimulation of the internal segment of the Globus Pallidus: experimental evidence in humans. Soc. Neurosci. Abstr. 20:1994;729.7.
12. Hallet M. Physiology of basal ganglia disorders: an overview. Can. J. Neurol. Sci. 20:1993;177-183.
13. Hazrati L.N., Parent A. Differential patterns of arborization of striatal and subthalamic fibers in the two pallidal segments in primates. Brain Res. 598:1992;311-315.
14. Laitinen L.V., Bergenheim T., Hariz M.I. Leskell's posteroventral pallidotomy in the treatment of Parkinson's disease. J. Neurosurg. 76:1992;53-61.
15. Marsden C.D., Obeso J.A. The function of the basal ganglia and the paradox of stereotaxic surgery in Parkinson's disease. Brain. 117:1994;877-897.
16. Parent A., Cote P.Y., Lavoie B. Chemical anatomy of primate basal ganglia. Prog. Neurobiol. 46:1995;131-197.
17. Parent A., Hazrati L.N. Functional anatomy of the basal ganglia. I. The cortico-basal ganglia thalamo-cortical loop. Brain Res. Rev. 20:1995;91-127.
18. Smith Y., Wichmann T., DeLong M.R. Synaptic innervation of neurons in the internal pallidal segment by the subthalamic nucleus and the external pallidum in monkeys. J. Comp. Neurol. 343:1994;297-318.
19. Snyder, R.S. and Lee, J.C., A Stereotaxic Atlas of the Monkey Brain, University of Chicago Press, Chicago, 1961.