Induction of locomotor activity by the glutamate antagonist DNQX injected into the ventral tegmental area

Brain Research

Volumn 728, Issue 2, 1996, Pages 209-214

  Dalia, Asad ^a   Uretsky, Norman J ^a   Wallace, Lane J ^a  

^a OHIO STATE UNIVERSITY   (United States)

Author keywords

Amphetamine; DNQX; Locomotor activity; Ventral tegmental area

Indexed keywords

6,7 DINITRO 2,3 QUINOXALINEDIONE; AMPA RECEPTOR; AMPHETAMINE; DOPAMINE RECEPTOR; DOPAMINE RECEPTOR BLOCKING AGENT; GLUTAMATE RECEPTOR ANTAGONIST; HALOPERIDOL; METIROSINE; RESERPINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CIRCLING BEHAVIOR; CONTROLLED STUDY; HISTOLOGY; LOCOMOTION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; VENTRAL TEGMENTUM;

EID: 0030605829     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-8993(96)00399-X     Document Type: Article

References (29)

1. [1] Beckstead, R.M., An autoradiographic examination of corticocortical and subcortical projections of the mediodorsal-projection (prefrontal) cortex in the rat, J. Comp. Neurol., 184 (1979) 43-62.
2. [2] Carlson, A., The current status of the dopamine hypothesis of schizophrenia, Neuropsychopharmacology, 1 (1988) 179-186.
3. [3] Dawbarn, D. and Pycock, C.J., Motor effects following application of putative excitatory amino acid antagonists to the region of the mesencephalic dopamine cell bodies in the rat, Arch. Pharmacol., 318 (1981) 100-104.
4. [4] Galey, D. and Le Moal, M., Locomotor activity after various radiofrequency lesions of the limbic brain area in the rat. Evidence for a particular role of the ventral mesencephalic tegmentum, Life Sci., 19 (1976) 677-684.
5. [5] Goldstein, M. and Deutch, A.Y., Dopaminergic mechanisms in the pathogenesis of schizophrenia, FASEB J., 6 (1992) 2413-2421.
6. [6] Grace, A.A., Cortical regulation of subcortical dopamine systems and its possible relevance to schizophrenia, J. Neural Transm., 91 (1993) 111-134.
7. [7] Honore, T., Davies, S.N., Drejer, J., Fletcher, E.J., Jacobsen, P., Lodge, D. and Nielsen, F.E., Quinoxalinediones: potent competitive non-NMDA glutamate receptor antagonists, Science, 241 (1988) 701-703.
8. [8] Hooks, M.S. and Kalivas, P.W., Involvement of dopamine and excitatory amino acid transmission in novelty-induced motor activity, J. Pharmacol. Exp. Ther., 269 (1994) 976-988.
9. [9] Joyce, E.M. and Iversen, S.D., The effect of morphine applied locally to mesencephalic dopamine cell bodies on spontaneous motor activity in the rat, Neurosci. Lett., 14 (1979) 207-212.
10. [10] Kaddis, F.G., Uretsky, N.J. and Wallace, L.J., DNQX in the nucleus accumbens inhibits cocaine-induced conditioned place preference, Brain Res., 697 (1995) 76-82.
11. [11] Kaddis, F.G., Wallace, L.J. and Uretsky, N.J., AMPA/kainate antagonists in the nucleus accumbens inhibit locomotor stimulatory response to cocaine and dopamine agonists, Pharmacol. Biochem. Behav., 46 (1993) 703-708.
12. [12] Kalivas, P.W., Neurotransmitter regulation of dopamine neurons in the ventral tegmental area, Brain Res. Rev., 18 (1993) 75-113.
13. 1 receptors modulate glutamate transmission in the ventral tegmental area, J. Neurosci., 15 (1995) 5379-5388.
14. [14] Kalivas, P.W., Duffy, P. and Barrow, J., Regulation of the mesocorticolimbic dopamine system by glutamic acid receptor subtypes, J. Pharmacol. Exp. Ther., 251 (1989) 378-387.
15. [15] Kalivas, P.W., Nemeroff, C.B. and Prange, A.J., Jr., Increase in spontaneous motor activity following infusion of neurotensin into the ventral tegmental area, Brain Res., 229 (1981) 525-529.
16. [16] Kelley, A.E., Stinus, L. and Iversen, S.D., Behavioral activation induced in the rat by substance P infusion into ventral tegmental area: implication of dopaminergic A10 neurons, Neurosci. Lett., 11 (1979) 335-339.
17. [17] Layer, R.T., Uretsky, N.J. and Wallace, L.J., Effects of the AMPA/kainate receptor antagonist DNQX in the nucleus accumbens on drug-induced conditioned place preference, Brain Res., 617 (1993) 267-273.
18. [18] Leikola-Pelho, T. and Jackson, D.M., Preferential stimulation of locomotor activity by ventral tegmental microinjections of (-)-nicotine, Pharmacol. Toxicol., 70 (1992) 50-52.
19. [19] LeMoal, M. and Simon, H., Mesocorticolimbic dopaminergic network: functional and regulator roles, Physiol. Rev., 71 (1991) 155-234.
20. [20] Mogenson, G.J., Wu, M. and Manchanda, S.K., Locomotor activity initiated by microinfusions of picrotoxin into the ventral tegmental area, Brain Res., 161 (1979) 311-319.
21. [21] Murase, S., Grenhoff, J., Chouvet, G., Gonon, F.G. and Svensson, T.H., Prefrontal cortex regulates burst firing and transmitter release in rat mesolimbic dopamine neurons studied in vivo, Neurosci. Lett., 157 (1993) 53-56.
22. [22] Narayanan, S., Willins, D., Dalia, A., Wallace, L.J. and Uretsky, N.J., Role of dopaminergic mechanisms in the stimulatory effects of MK-801 injected into the ventral tegmental area and the nucleus accumbens, Pharmacol. Biochem. Behav., 54 (1996) 565-573.
23. [23] Paxinos, G. and Watson, C., The Rat Brain in Stereotaxic Coordinates, Academic Press, Sydney, 1982.
24. [24] Shreve, P.E. and Uretsky, N.J., AMPA, kainic acid, and N-methyl-D-aspartic acid stimulate locomotor activity after injection into the substantia inominata/lateral preoptic area, Pharmacol. Biochem. Behav., 34 (1989) 101-106.
25. [25] Suaud-Chagny, M.F., Chergui, K., Chouvet, G. and Gonon, F., Relationship between dopamine release in the rat nucleus accumbens and the discharge activity of dopaminergic neurons during local in vivo application of amino acids in the ventral tegmental area, Neuroscience, 49 (1992) 63-72.
26. [26] Willins, D.L., Wallace, L.J., Miller, D.D. and Uretsky, N.J., α-Amino-3-hydroxy-5-methylisoxazole-4-propionate/kainate receptor antagonists in the nucleus accumbens and ventral pallidum decrease the hypermotility response to psychostimulant drugs, J. Pharmacol. Exp. Ther., 260 (1992) 1145-1151.
27. [27] Wirtshafter, D. and Klitenick, M.A., Comparative studies of locomotor behavior following microinjections of muscimol into various sites in the paramedian tegmentum, Pharmacol. Biochem. Behav., 32 (1989) 625-628.
28. [28] Wirtshafter, D., Trifunovic, R. and Krebs, J.C., Behavioral and biochemical evidence for a functional role of excitatory amino acids in the median raphe nucleus, Brain Res., 482 (1989) 225-234.
29. [29] Wise, R.A. and Bozarth, M.A., Psychomotor stimulant theory of addiction, Psychol. Rev., 94 (1985) 469-492.