Solid phase synthesis of oligodeoxynucleoside phosphorodithioates by a phosphotriester method using a chemoselective coupling reagent

Tetrahedron Letters

Volumn 37, Issue 44, 1996, Pages 8041-8044

  Kehler, Jan ^a   Püschl, Ask ^a   Dahl, Otto ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

OLIGODEOXYNUCLEOSIDE PHOSPHORODITHIOATE; OLIGODEOXYNUCLEOTIDE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; DRUG SYNTHESIS; NUCLEAR MAGNETIC RESONANCE; TECHNIQUE;

OXY;

EID: 0030605106     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/0040-4039(96)01820-5     Document Type: Article

References (17)

1. 1. Marshall, W. S.; Caruthers M. H., Science 1993, 259, 1564-1570.
2. 2a. Okyuszek, A. ; Sierzchata, A.; Sochacki, M., Stec, J. W., Tetrahedron Lett. 1992, 33, 7585-7588.
3. 2b. Okyuszek, A. ; Sierzchata, A.; Fearon, K. L.; Stec, J. W., J. Org. Chem. 1995, 60, 6998-7005.
4. 3. Wiesler, W. T.; Caruthers M. H., J. Org. Chem. 1996, 61, 4272-4281.
5. 4a. Eldrup, A. B.; Bjergârde K.; Felding J. ; Kehler, J.; Dahl, O., Nucleic Acids Research 1994, 22, 1797-1804, and references cited therein.
6. 4b. Eldrup, A. B.; Felding J. ; Kehler, J.; Dahl, O., Tetrahedron Lett. 1995, 36, 6127-6130.
7. 5. Yau, E.K.; Yun-Xi, M. and Caruthers, M. H., Tetrahedron Lett. 1990, 31, 1953-1956.
8. 6. Kehler, J.; Püschl, A. and Dahl, O: Nucleosides and Nucleotides, submitted.
9. 7. Høeg-Jensen, T.; Olsen, C. E. and Holm, A., J. Org. Chem. , 1995, 59, 1257-1263.
10. 8. Wijkmans, J. C. H. M.; Blok, F. A. A.; van der Marel, G. A.; van Boom, J. H. and Bloemhoff, W., Tetrahedron Lett. 1995, 36, 4643-4646.
11. 9. Kehler, J.; Püschl, A. and Dahl, O: Acta Chem. Scand, in press.
12. +H).
13. 11. Bayer, E., Bleicher, K. , Maier, M., Z. Naturforsch. 1995, 50b, 1096-1100.
14. 12. Reese, C. B. and Richards, K. H., Tetrahedron Lett. 1985, 26, 2245-2248.
15. 13. de Vroom, E., Fidder, A., Marugg, J. E., van der Marel, G. A. and van Boom, J. H., Nucleic Acids Research, 1986, 14, 5885-5900.
16. 14. Hashmi, S. A. N., Adiraj, M., Kumar, A. and Katti, S. B., Nucleosides and Nucleotides, 1994, 13, 1059-1067.
17. 15. Kodra,, J. T.; Kehler, J. and Dahl, O., Nucleic Acids Research, 1995, 23, 3349-3350.