Iodide acceleration in the Pd-catalyzed coupling of aromatic 1,2-ditriflates with alkynes: Synthesis of enediynes

Tetrahedron Letters

Volumn 37, Issue 44, 1996, Pages 7901-7904

  Powell, Noel A ^a   Rychnovsky, Scott D ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

alkyne; aromatic ditriflates; aryl enediyne; Hagihara reaction; Pd cross coupling

Indexed keywords

ALKYNE DERIVATIVE;

ARTICLE; DRUG SYNTHESIS; REACTION ANALYSIS; TECHNIQUE;

EID: 0030605058     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/0040-4039(96)01698-X     Document Type: Article

References (28)

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27. 2 were stirred under Ar at rt for 10 min. Then, CuI was added, and the dark brown solution was stirred for another 10 min. Finally, alkyne was added, and the yellow solution was heated in 70 °C oil bath.
28. 2: C, 81.24; H, 8.45. Found: C, 80.89; H, 8.32.