Prediction of flux through polydimethylsiloxane membranes using atomic charge calculations: Application to an extended data set

International Journal of Pharmaceutics

Volumn 137, Issue 2, 1996, Pages 149-158

  Chen, Yisheng ^a,b   Vayumhasuwan, Panida ^a   Matheson, Lloyd E ^a  

^a UNIVERSITY OF IOWA   (United States)

^b ABBOTT LABORATORIES   (United States)

Author keywords

Atomic charge; Molecular modeling; Permeability; Polydimethylsiloxane membrane; Prediction; Quantitative structure transportability relationship; Steady state flux

Indexed keywords

BENZENE; BENZENE DERIVATIVE; BENZIMIDAZOLE; BENZIMIDAZOLE DERIVATIVE; DIMETICONE; HETEROCYCLIC COMPOUND; IMIDAZOLE; INDOLE; ISOQUINOLINE; ISOQUINOLINE DERIVATIVE; NAPHTHALENE DERIVATIVE; PYRIDINE; PYRIDINE DERIVATIVE; PYRIMIDINE; PYRIMIDINE DERIVATIVE; QUINOLINE; QUINOLINE DERIVATIVE; SALICYLIC ACID METHYL ESTER; THIOPHENE; THIOPHENE DERIVATIVE; TRIAZOLE; TRIAZOLE DERIVATIVE;

ARTICLE; MEMBRANE PERMEABILITY; MOLECULAR MODEL; MOLECULAR WEIGHT; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; SOLUBILITY;

EID: 0030604690     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/0378-5173(96)89422-1     Document Type: Article

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