Chronic repeated cocaine administration increases dopamine D1 receptor-mediated signal transduction

European Journal of Pharmacology

Volumn 318, Issue 1, 1996, Pages 31-35

  Unterwald, Ellen M ^a,b   Fillmore, Jonathan ^b   Kreek, Mary Jeanne ^b  

^a NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

^b ROCKEFELLER UNIVERSITY   (United States)

Author keywords

Adenylyl cyclase; cAMP; Caudate putamen; Nucleus accumbens; SKF 82958

Indexed keywords

3 ALLYL 6 CHLORO 2,3,4,5 TETRAHYDRO 7,8 DIHYDROXY 1 PHENYL 1H 3 BENZAZEPINE; ADENYLATE CYCLASE; COCAINE; DOPAMINE 1 RECEPTOR; DOPAMINE RECEPTOR STIMULATING AGENT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN REGION; CONTROLLED STUDY; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; PUTAMEN; RAT; SENSITIZATION; SIGNAL TRANSDUCTION;

ANIMALS; BENZAZEPINES; CAUDATE NUCLEUS; COCAINE; CYCLIC AMP; DOPAMINE AGONISTS; MALE; NUCLEUS ACCUMBENS; RATS; RATS, INBRED F344; RECEPTORS, DOPAMINE D1; SIGNAL TRANSDUCTION; TIME FACTORS;

EID: 0030604237     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(96)00841-2     Document Type: Article

References (15)

1. Alburges, M.E., N. Narang and J.K. Wamsley, 1993, Alterations in the dopaminergic receptor system after chronic administration of cocaine, Synapse 14, 314.
2. Downs, A.W. and N.B. Eddy, 1932, The effect of repeated doses of cocaine on the rat, J. Pharmacol. Exp. Ther. 46, 199.
3. 1 dopamine receptor sensitivity within the rat nucleus accumbens, J. Pharmacol. Exp. Ther. 258, 882.
4. Higashi, H., K. Inanaga, S. Nishi and N. Uchimura, 1989, Enhancement of dopamine actions on rat nucleus accumbens neurones in vitro after methamphetamine pre-treatment, J. Physiol. (London) 408, 587.
5. 1 receptor agonists for stimulating adenylyl cyclase in squirrel monkey and rat, Eur. J. Pharmacol. 246, 39.
6. Kalivas, P.W., P. Duffy, L.A. DuMars and C. Skinner, 1988, Neurochemical and behavioral effects of acute and daily cocaine, J. Pharmacol. Exp. Ther. 245, 485.
7. Kelley, P.H. and S.D. Iversen, 1975, Selective 6-OHDA-induced destruction of mesolimbic dopamine neurons: abolition of psychostimulant-induced locomotor activity in rats, Eur. J. Pharmacol. 40, 45.
8. Lowry, O.H., N.J. Rosebrough, A.L. Farr and R.J. Randall, 1951, Protein measurement with the Folin phenol reagent, J. Biol. Chem. 193, 265.
9. 1 dopamine receptor function in rat nucleus accumbens and striatum, Brain Res. 573, 331.
10. oα in discrete regions of rat brain, J. Neurochem. 55, 1079.
11. 2 dopamine receptors in efflux of cyclic AMP from rat striatum, Nature 294, 366.
12. Striplin, C.D. and P.W. Kalivas, 1993, Robustness of G protein changes in cocaine sensitization shown with immunoblotting, Synapse 14, 10.
13. Terwilliger, R.Z., D. Beitner-Johnson, K.A. Sevarino, S.M. Crain and E.J. Nestler, 1991, A general role for adaptations in G-proteins and the cyclic AMP system in mediating the chronic actions of morphine and cocaine on neuronal function, Brain Res. 548, 100.
14. Unterwald, E.M., A. Ho., J.M. Rubenfeld and M.J. Kreek, 1994, Time course of the development of behavioral sensitization and dopamine receptor up-regulation during binge cocaine administration, J. Pharmacol. Exp. Ther. 270, 1387.
15. 1 receptors enhances the effects of dopamine receptor agonists, Eur. J. Pharmacol. 191, 497.