A small volume spacer for use with a breath-operated pressurised metered dose inhaler

International Journal of Pharmaceutics

Volumn 142, Issue 1, 1996, Pages 129-133

  Hardy, J G ^a   Jasuja, A K ^b   Frier, M ^c   Perkins, A C ^c  

^a Norton Healthcare   (United Kingdom)

^b CRANFIELD UNIVERSITY   (United Kingdom)

^c QUEEN S MEDICAL CENTRE   (United Kingdom)

Author keywords

Breath operated inhaler; Oropharyngeal drug deposition; Small volume spacer

Indexed keywords

BECLOMETASONE DIPROPIONATE; SALBUTAMOL;

ADULT; AEROSOL; APPARATUS; ARTICLE; DRUG DELIVERY SYSTEM; DRUG DISPOSITION; HUMAN; HUMAN EXPERIMENT; INHALATIONAL DRUG ADMINISTRATION; NORMAL HUMAN; PARTICLE SIZE; PRIORITY JOURNAL; SCINTILLATION CAMERA;

EID: 0030603993     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/0378-5173(96)04655-8     Document Type: Article

References (7)

1. Ashworth, H.L., Wilson, C.G., Sims, E.E., Wotton, P.K. and Hardy, J.G., Delivery of propellant soluble drug from a metered dose inhaler. Thorax, 46 (1991) 245-247.
2. Farr, S.J., Rowe, A.M., Rubsamen, R. and Taylor, G., Aerosol deposition in the human lung following administration from a microprocessor controlled pressurised metered dose inhaler. Thorax, 50 (1995) 639-644.
3. Fergusson, R.J., Lenney, J., McHardy, G.J.R. and Crompton, G.K., The use of a new breath-actuated inhaler by patients with severe airflow obstruction. Eur. Respir. J., 4 (1991) 172-174.
4. Forge, N.I., Mountford, P.J. and O'Doherty, M.J., Quantification of technetium-99m lung radioactivity from planar images. Eur. J. Nucl. Med., 20 (1993) 10-15.
5. Hardy, J.G., Everard, M.L., Coffiner, M. and Fossion, J., Lung deposition of a nacystelyn metered dose inhaler formulation. J. Aerosol Med., 6 (1993) 37-43.
6. Inhalanda, PA/PH/Exp. 12/T (91) 6 ANP. Pharmeuropa, 5 (1993) 316-327.
7. Newman, S.P., Weisz, A.W.B., Talaee, N. and Clarke, S.W., Improvement of drug delivery with a breath actuated pressurised aerosol for patients with poor inhaler technique. Thorax, 46 (1991) 712-716.