Intracellularly biorecognizable derivatives of 5-fluorouracil. Implications for site-specific delivery in the human condition

Biochemical Pharmacology

Volumn 52, Issue 6, 1996, Pages 957-962

  Putnam, David A ^a   Shiah, Jane Guo ^a   Kopeček, Jindřich ^a,b  

^a UNIVERSITY OF UTAH   (United States)

^b Department of Electrical and Computer Engineering   (United States)

Author keywords

5 fluorouracil; biorecognition; cathepsin B; cathepsin H; polymer carriers; site specific release

Indexed keywords

CATHEPSIN B; CATHEPSIN H; COPOLYMER; DRUG CARRIER; FLUOROURACIL; FLUOROURACIL DERIVATIVE; LYSOSOME ENZYME; N (2 HYDROXYPROPYL)METHACRYLAMIDE; OLIGOPEPTIDE;

ARTICLE; BIODEGRADATION; CANCER CELL CULTURE; CATALYSIS; COLON ADENOCARCINOMA; CONTROLLED STUDY; DRUG CONJUGATION; DRUG RELEASE; DRUG TARGETING; HUMAN; HUMAN CELL; HYPOTHESIS; PRIORITY JOURNAL;

EID: 0030603965     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-2952(96)00410-8     Document Type: Article

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