Evidence for tumor necrosis factor α as a mediator of the toxicity of a cyclooxygenase inhibitor in Gram-negative sepsis

European Journal of Pharmacology

Volumn 307, Issue 2, 1996, Pages 191-199

  Campanile, Franca ^a   Giampietri, Antonio ^a   Grohmann, Ursula ^a   Belladonna, Maria L ^a   Fioretti, Maria C ^a   Puccetti, Paolo ^a  

^a UNIVERSITY OF PERUGIA   (Italy)

Author keywords

Cyclooxygenase inhibitor; Gram negative sepsis; Indomethacin; Sepsis; TMF (tumor necrosis factor)

Indexed keywords

INDOMETACIN; INDOMETACIN MEGLUMINE; MESSENGER RNA; MONOCLONAL ANTIBODY; N(G) METHYLARGININE; NITRIC OXIDE; PENTOXIFYLLINE; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE INHIBITOR; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA ANTIBODY;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; EXPERIMENTAL INFECTION; FEMALE; GENE AMPLIFICATION; GENE EXPRESSION; GRAM NEGATIVE SEPSIS; INTRAPERITONEAL DRUG ADMINISTRATION; MACROPHAGE; MALE; MEDIATOR; MORTALITY; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; SPLEEN; SUBCUTANEOUS DRUG ADMINISTRATION;

EID: 0030603781     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-2999(96)00269-5     Document Type: Article

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