The effects of abused inhalants on mouse behavior in an elevated plus-maze

European Journal of Pharmacology

Volumn 312, Issue 2, 1996, Pages 131-136

  Bowen, Scott E ^a   Wiley, Jenny L ^a   Balster, Robert L ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

1,1,1 Trichloroethane; Anxiolytic; Flurothyl; Inhalant abuse; Methoxyflurane; Mouse; Plus maze; Toluene

Indexed keywords

1,1,1 TRICHLOROETHANE; CENTRAL DEPRESSANT AGENT; DIAZEPAM; FLUROTHYL; METHOXYFLURANE; TOLUENE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BEHAVIOR; CONTROLLED STUDY; DISCRIMINATIVE STIMULUS; DOSE RESPONSE; DRUG ABUSE; INHALATIONAL DRUG ADMINISTRATION; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; MOTOR ACTIVITY; MOUSE; NONHUMAN; PRIORITY JOURNAL;

EID: 0030603212     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-2999(96)00459-1     Document Type: Article

References (35)

1. Adler, M.W., 1975, Pharmacology of flurothyl: laboratory and clinical applications, in: Current Developments in Psychopharmacology, eds. W. Essman and L. Valzelli (Spectrum Publications, New York) p. 31.
2. Arif, A.E., M. Grant and V. Vavaratnam (eds.), 1988, Abuse of Volatile Solvents and Inhalants: Papers Presented at W.H.O. Advisory Meeting, Centre for Drug Research International Monograph Series No. 1, (W.H.O. Collaborating Centre for Research and Training in Drug Dependence, Universiti Sains Malaysia, Miden, Pulau Pinang, Malaysia).
3. Balster, R.L., 1987, Abuse potential evaluation of inhalants, Drug Alcohol Depend. 49, 7.
4. Balster, R.L., V.C. Moser and W.L. Woolverton, 1982, Concurrent measurement of solvent vapor concentrations and effects on operant behavior using a dynamic exposure system, J. Pharmacol. Methods 8, 299.
5. Barrett, J.E. and J.M. Witkin, 1991, Buspirone in animal models of anxiety, in: Buspirone: Mechanisms and Clinical Aspects, eds. G. Tunnicliff, A.S. Eison and D.P. Taylor (Academic Press, San Diego, CA) p. 37.
6. Beauvais, F., 1992, Volatile solvent abuse: trends and patterns, in: Inhalant Abuse: a Volatile Research Agenda, eds. C. Sharp, F. Beauvais and R. Spence (National Institute on Drug Abuse Monograph 129, U.S. Department of Health and Human Services, Rockville, MD) p. 13.
7. Bowen, S.E. and R.L. Balster, 1994, The effects of abused inhalants on locomotor activity in mice, in: Problems of Drug Dependence 1994: Proceedings of the 56th Annual Scientific Meeting, Vol. 2, ed. L.S. Harris (National Institute on Drug Abuse Monograph 153, U.S. Department of Health and Human Services, Rockville, MD) p. 426.
8. Bowen, S.E. and R.L. Balster, 1996, Effects of inhaled 1,1,1-trichloroethane on locomotor activity in mice, Neurotoxicol. Teratol. (in press).
9. Bowen, S.E., J.L. Wiley, M.E. Tokarz, and R.L. Balster, 1995, Effects of abused inhalants on an elevated plus-maze task in mice, Soc. Neurosci. Abstr. 21, 726.
10. Bowen, S.E., J.L. Wiley, E.B. Evans, M.E. Tokarz and R.L. Balster, 1996, Functional observational battery comparing effects of ethanol, 1,1,1-trichloroethane, ether and flurothyl, Neurotoxicol. Teratol. (in press).
11. Brett, R.R. and J.A. Pratt, 1990, Chronic handling modifies the anxiolytic effect of diazepam in the elevated plus-maze, Eur. J. Pharmacol. 178, 135.
12. Cruz, A.P.M., F. Frei and F.G. Graeff, 1994, Ethopharmacological analysis of rat behavior on the elevated plus-maze, Pharmacol. Biochem. Behav. 49, 171.
13. Daniel, W.W., 1978, Applied Nonparametric Statistics (Houghton Mifflin Company, Boston) p. 200.
14. Emmanouil, D.E., C.H. Johnson and R.M. Quack, 1994, Nitrous oxide anxiolytic effect in mice in the elevated plus maze: mediation by benzodiazepine receptors. Psychopharmacology 115, 167.
15. Evans, E.B. and R.L. Balster, 1991, CNS depressant effects of volatile organic solvents, Neurosci. Biobehav. Rev. 15, 233.
16. Evans, E.B. and R.L. Balster, 1992, Effects of methoxyflurane and flurothyl in mice trained to discriminate pentylenetetrazol from saline, Behav. Pharmacol. 3, 465.
17. Geller, I., R.J. Hartmann, S.R. Randle and E.M. Gause, 1983, Toluene inhalation and anxiolytic activity: possible synergism with diazepam, Pharmacol. Biochem. Behav. 19, 899.
18. Giusti, P., G. Guidetti, E. Costa and A. Guidotti, 1991, The preferential antagonism of pentylenetetrazol proconflict responses differentiates a class of anxiolytic benzodiazepines with potential antipanic action, J. Pharmacol. Exp. Ther. 257, 1062.
19. Knisely, J.S., D.C. Rees and R.L. Balster, 1990, Discriminative stimulus properties of toluene in the rat, Neurotoxicol. Teratol. 12, 129.
20. Lister, R.G., 1987, The use of a plus-maze to measure anxiety in the mouse, Psychopharmacology 92, 180.
21. Marjot, R. and A.A. McLeod, 1989, Chronic nonneurological toxicity from volatile solvent substance abuse, Hum. Toxicol. 8, 301.
22. Moser, V.C. and R.L. Balster, 1985, Acute motor and lethal effects of inhaled toluene, 1,1,1-trichloroethane, halothane, and ethanol in mice: effects of exposure duration, Toxicol. Appl. Pharmacol. 77, 285.
23. Moser, V.C., E.M. Coggeshall and R.L. Balster, 1985, Effects of xylene isomers on operant responding and motor performance in mice, Toxicol. Appl. Pharmacol. 80, 293.
24. Pellow, S. and S.E. File, 1986, Anxiolytic and anxiogenic drug effects on exploratory activity in an elevated plus-maze: a novel test of anxiety in the rat, Pharmacol. Biochem. Behav. 24, 525.
25. Pellow, S., P. Chopin, S.E. File and M. Briley, 1985, Validation of open:closed arm entries in an elevated plus-maze as a measure of anxiety in the rat J. Neurosci. Methods 14, 149.
26. Rees, D.C., E. Coggeshall and R.L. Balster, 1985, Inhaled toluene produces pentobarbital-like discriminative stimulus effects in mice, Life Sci. 37, 1319.
27. Rees, D.C., J.S. Knisely, R.L. Balster, S. Jordan and T.J. Breen, 1987a, Pentobarbital-like discriminative stimulus properties of halothane, 1,1,1-trichloroethane, isoamyl nitrite, flurothyl and oxazepam in mice, J. Pharmacol. Exp. Ther. 241, 507.
28. Rees, D.C., J.S. Knisely, T.J. Breen and R.L. Balster, 1987b, Toluene, halothane, 1,1,1-trichloroethane and oxazepam produce ethanol-like discriminative stimulus effects in mice. J. Pharmacol. Exp. Ther. 243, 931.
29. Rees, D.C., J.S. Knisely, S. Jordan and R.L. Balster, 1987c, Discriminative stimulus properties of toluene in the mouse, Toxicol. Appl. Pharmacol. 88, 97.
30. Shigeta, S., T. Misawa, and H. Aikawa, 1980, Effects of concentration and duration of toluene exposure on sidman avoidance in rats, Neurobehav. Toxicol. 2, 85.
31. Siegel, S. and N.J. Castellan, 1988, Nonparametric Statistics for the Behavioral Sciences, 2nd edn. (MacGraw-Hill, New York) p. 206.
32. Vogel, J.R., B. Beer and D.E. Clody, 1971, A simple and reliable conflict procedure for testing antianxiety agents, Psychopharmacologia 21 (1), 1.
33. Wiley, J.L., A.F. Crisrello and R.L. Balster, 1995, Effects of site-selective NMDA receptor antagonists in the elevated plus-maze model of anxiety in mice, Eur. J. Pharmacol. 294, 101.
34. Wood, R.W., J.B. Coleman, R. Schuler, and C. Cox, 1984, Anticonvulsant and antipunishment effects of toluene, J. Pharmacol. and Exp. Ther. 230, 407.
35. Woolverton, W.L. and R.L. Balster, 1981, Behavioral and lethal effects of combinations of oral ethanol and inhaled 1,1,1-trichloroethane in mice, Toxicol. Appl. Pharmacol. 59, 1.