Alkynyl phosphates are potent inhibitors of serine enzyme

FEBS Letters

Volumn 392, Issue 2, 1996, Pages 117-120

  Segal, Dina ^a   Shalitin, Channa ^a   Shalitin, Yechiel ^a   Fischer, David R ^b   Stang, Peter J ^b  

^a TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

^b UNIVERSITY OF UTAH   (United States)

Author keywords

Alkynyl phosphate; Covalent inhibition; Serine enzyme

Indexed keywords

ALKYNYL GROUP; ALKYNYL PHOSPHATE; CHOLINESTERASE; CHOLINESTERASE INHIBITOR; CHYMOTRYPSIN; ELASTASE; ESTERASE; KALLIKREIN; PARAOXON; PHOSPHATE; PROTEINASE; PROTEINASE INHIBITOR; SUBTILISIN; THROMBIN; TRIACYLGLYCEROL LIPASE; TRYPSIN; UNCLASSIFIED DRUG;

ARTICLE; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME INHIBITION; ENZYME KINETICS; HUMAN; IN VITRO STUDY; ISOTOPE LABELING; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

EID: 0030603108     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-5793(96)00795-8     Document Type: Article

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