Molecular sieves promote stereocontrolled αα-disaccharide formation via direct dimerization of free sugars

Tetrahedron Letters

Volumn 37, Issue 35, 1996, Pages 6279-6282

  Posner, Gary H ^a   Bull, D Scott ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DISACCHARIDE;

ARTICLE; CARBOHYDRATE SYNTHESIS; REACTION ANALYSIS; STEREOCHEMISTRY; TECHNIQUE;

EID: 0030603046     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/0040-4039(96)01376-7     Document Type: Article

References (29)

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24. -2 0.035 0.029 0.022 0.027
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27. 28 (αα: 94.4 ppm, J=169 Hz; α of αβ: 99.5 ppm, J=171 Hz; β of αβ: 104.1 ppm, J=160 Hz; ββ: 99.3 ppm, J=163 Hz) in the crude product mixture, and this method was confirmed by normal phase HPLC analysis. Column chromatography gave the pure disaccharide products αα (481 mg, 49% yield); αβ (164 mg, 17% yield); ββ (25 mg, 2.5% yield).
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