Excitation of rat cutaneous nociceptors by noxious cold

Neuroscience Letters

Volumn 213, Issue 1, 1996, Pages 53-56

  Simone, Donald A ^a   Kajander, Keith C ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Electrophysiology; Nerve fibers; Pain; Sensation

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COLD; CONTROLLED STUDY; ELECTROPHYSIOLOGY; MALE; NOCICEPTION; NONHUMAN; PAIN; PRIORITY JOURNAL; RAT; SENSORY NERVE; SKIN;

EID: 0030602841     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/0304-3940(96)12838-X     Document Type: Article

References (28)

1. [1] Beitel, R.E. and Dubner, R., Response of unmyelinated (C) polymodal nociceptors to thermal stimuli applied to monkeys' face, J. Neurophysiol., 39 (1976) 1160-1175.
2. [2] Bessou, P. and Perl, E.R., Response of cutaneous sensory units with unmyelinated fibers to noxious stimuli, J. Neurophysiol., 32 (1969) 1025-1043.
3. [3] Burgess, P.R. and Perl, E.R., Cutaneous mechanoreceptors and nociceptors. In A. Iggo (Ed.), Handbook of Sensory Physiology, Somatosensory System, Springer, Berlin, (1979) 29-78.
4. [4] Campbell, J.N. and Meyer, R.A., Primary afferents and hyperalgesia. In T.L. Yaksh (Ed.), Spinal Afferent Processing, Plenum Press, New York, 1986, pp. 59-81.
5. [5] Croze, S., Duclaux, R. and Kenshalo, D.R., The thermal sensitivity of the polymodal nociceptors in the monkey, J. Physiol. (London), 263 (1976) 539-562.
6. [6] Darian-Smith, I., Johnson, K.O. and Dykes, R., 'Cold' fiber population innervating palmar and digital skin of the monkey: responses to cooling pulses, J. Neurophysiol., 36 (1973) 325-346.
7. [7] Douglas, W.W., Ritchie, J.M. and Straub, R.W., The role of non-myelinated fibers in signaling cooling of the skin, J. Physiol. (London), 150 (1960) 266-283.
8. [8] Dubner, R., Sumino, R. and Wood, W.I., A peripheral 'cold' fiber population responsive to innocuous and noxious thermal stimuli applied to monkey's face, J. Neurophysiol., 38 (1975) 1373-1389.
9. [9] Frost, S.A., Raja, S.N., Campbell, J.N., Meyer, R.A. and Khan, A.A., Does hyperalgesia to cooling stimuli characterize patients with sympathetically maintained pain (reflex sympathetic dystrophy)? In R. Dubner, G.F. Gebhart and M.R. Bond (Eds.), Proceedings of the Vth World Congress on Pain, Elsevier, Amsterdam, 1988, pp. 151-156.
10. [10] Fruhstorfer, H. and Lindblom, U., Sensibility abnormalities in neuralgic patients studied by thermal and tactile pulse stimulation. In C. von Euler, O. Franzen, U. Lindblom and D. Ottoson, (Eds.), Somatosensory Mechanisms, Vol. 41, (Wenner-Gren International Symposium), Macmillan, London, 1984, pp. 353-361.
11. [11] Georgopoulos, A., Functional properties of primary afferent units probably related to pain mechanisms in primate glabrous skin, J. Neurophysiol., 39 (1976) 71-83.
12. [12] Georgopoulos, A., Stimulus-response relations in high-threshold mechanothermal fibers innervating primate glabrous skin, Brain Res., 128 (1977) 547-552.
13. [13] Handwerker, H.O. and Kobal, G., Psychophysiology of experimentally induced pain, Physiol. Rev., 73 (1993) 639-671.
14. [14] Hellon, R.F. Hensel, H. and Schäfer, K., Thermal receptors in the scrotum of the rat, J. Physiol. (London), 248 (1975) 349-357.
15. [15] Hensel, H., Thermoreceptors, Annu. Rev. Physiol., 36 (1974) 233-249.
16. [16] Hensel, H. and Iggo, A., Analysis of cutaneous warm and cold fibers in primates, Pflügers Arch., 329 (1971) 1-8.
17. [17] Iggo, A., Cutaneous thermoreceptors in primates and sub-primates, J. Physiol. (London), 200 (1969) 403-430.
18. [18] Kajander, K.C., Allen, B.J., Allard, B.A., Courteix, C. and Simone, D.A., Responses of rat C fiber nociceptors to noxious cold, Soc. Neurosci. Abstr., 12 (1994) 1379.
19. [19] Kumazawa, T. and Perl, E.R., Primate cutaneous sensory units with unmyelinated (C) afferent fibers, J. Neurophysiol., 40 (1977) 1325-1338.
20. [20] LaMotte, R.H. and Campbell, J.N., Comparison of responses of warm and nociceptive C fiber afferents in monkey with human judgments of thermal pain, J. Neurophysiol., 41 (1978) 509-528.
21. [21] LaMotte, R.H. and Thalhammer, J.G., Response properties of high-threshold cutaneous cold receptors in the primate, Brain Res., 244 (1982) 279-287.
22. [22] Leem, J.W., Willis, W.D. and Chung, J.M., Cutaneous sensory receptors in the rat foot, J. Neurophysiol., 69 (1993) 1684-1699.
23. [23] Lindblom, U. and Verrillo, R.T., Sensory functions in chronic neuralgia, J. Neurol. Neurosurg. Psychiatry, 42 (1979) 422-435.
24. [24] Lynn, B., The fiber composition of cutaneous nerves and the classification and response properties of cutaneous afferents, with particular reference to nociception, Pain Rev., 1 (1994) 172-183.
25. [25] Lynn, B. and Carpenter, S.E., Primary afferent units form the hairy skin of the rat hindlimb, Brain Res., 238 (1982) 29-43.
26. [26] Ochoa, J.L. and Yamitsky, D., The triple cold syndrome: cold hyperalgesia, cold hypesthesia and cold skin in peripheral nerve disease, Brain, 117 (1994) 185-197.
27. [27] Simone, D.A. and Kajander, K.C., A-delta nociceptors are excited by noxious cold stimuli, Soc. Neurosci. Abstr., 19 (1993) 324.
28. [28] Willis, Jr., W.D., The pain system. The neural basis of nociceptive transmission in the mammalian nervous system. In P.L. Gildenberg (Ed.), Pain and Headache, Vol. 8, Krager, New York, 1985, pp. 22-77.