A TTX-sensitive conductance underlying burst firing in isolated pyramidal neurons from rat neocortex

Brain Research

Volumn 741, Issue 1-2, 1996, Pages 1-12

  Guatteo, Ezia ^a   Franceschetti, Silvana ^b   Bacci, Alberto ^a   Avanzini, Giuliano ^b   Wanke, Enzo ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b DEPARTMENT OF NEUROSURGERY   (Italy)

Author keywords

burst firing; pyramidal neuron; sensorimotor cortex

Indexed keywords

4 AMINOPYRIDINE; NICKEL; SODIUM CHANNEL; TETRODOTOXIN;

ADOLESCENT; ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CALCIUM CURRENT; CONTROLLED STUDY; ELECTROPHYSIOLOGY; NEOCORTEX; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RAT;

ANIMALS; AXONS; CELLS, CULTURED; CEREBRAL CORTEX; COMPUTER SIMULATION; ELECTROPHYSIOLOGY; FLUORIDES; MEMBRANE POTENTIALS; NEURAL CONDUCTION; NICKEL; PATCH-CLAMP TECHNIQUES; PYRAMIDAL CELLS; RATS; RATS, WISTAR; TETRODOTOXIN;

EID: 0030602068     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(96)00866-9     Document Type: Article

References (44)

1. [1] Akaike, N. and Takahashi, K., Tetrodotoxin-sensitive calcium conducting channels in the rat hippocampal CA1 region, J. Physiol. (Lond.), 450 (1992) 529-546.
2. + -dependent theta-like rhythmicity in stellate cells of enthorinal cortex layer II, Nature, 342 (1989) 175-177.
3. + current in pyramidal neurons from rat sensorimotor cortex, J. Neurosci., 13 (1993) 660-673.
4. [4] Amitai, Y., Membrane potential oscillations underlying firing patterns in neocortical neurons, Neuroscience, 63 ( 1994) 151-161.
5. [5] Amitai, Y., Friedman, A., Connors, B.W. and Gutnick, M.J., Regenerative activity in apical dendrites of pyramidal cells in neocortex, Cereb. Cortex, 3 (1993) 26-38.
6. [6] Andreasen, M. and Hablitz, J.J., Kinetic properties of a transient outward current in rat neocortical neurons, J. Neurophysiol., 66 (1992) 1133-1142.
7. [7] Belluzzi, O., Sacchi, O. and Wanke, E., A fast transient outward current in the rat sympathetic neurone studied under voltage-clamp conditions, J. Physiol (Lond.), 358 (1985) 91-108.
8. [8] Bertollini, L., Biella, G., Wanke E., Avanzini, G. and de Curtis, M., Fluoride reversibly blocks HVA calcium currents in mammalian thalamic neurones, Neuroreport, 5 (1994) 553-556.
9. [9] Bigay, J., Deterre, P., Pfister, C. and Chabre, M., Fluoride complexes of aluminium or berillium act on G-proteins as reversibly bound analogues of the γ phosphate of GTP, EMBO J., 6 (1987) 2907-2913.
10. [10] Chagnac-Amitai, Y. and Connors, B.W., Synchronized excitation and inhibition driven by intrinsically bursting neurons in neocortex, J. Neurophysiol., 62 (1989) 1149-1162.
11. [11] Chagnac-Amitai, Y., Luhman, H.J. and Prince, D.A., Burst generating and regular spiking layer 5 pyramidal neurons of rat neocortex have different morphological feature, J. Comp. Neurol., 296 (1990) 598-613.
12. [12] Connors, B.W., Gutnick, M.J. and Prince, D.A., Electrophysiological properties of neocortical neurons in vitro, J. Neurophysiol., 48 (1982) 1302-1320.
13. [13] Di Francesco, D., Ducoret, P. and Robinson, R.B., Muscarinic modulation of cardiac rate at low acetylcholine concentrations, Science, 243 (1989) 669-671.
14. [14] Foehering, R.C. and Surmeier, D.J., Voltage-gated potassium currents in acutely dissociated rat cortical neurons, J. Neurophysiol., 70 (1993) 51-63.
15. [15] Franceschetti, S., Buzio, S., Sancini, G., Panzica, F. and Avanzini, G., Expression of intrinsic burting properties in neurons of maturing sensorimotor cortex, Neurosci. Lett., 162 (1993) 25-28.
16. [16] Franceschetti, S., Guatteo, E., Panzica, F., Sancini, G., Wanke, E. and Avanzini, G., Ionic mechanism underlying burst firing in pyramidal neurons: intracellular study in rat sensorimotor cortex, Brain Res., 696 (1995) 127-139.
17. [17] Friedman, A. and Gutnick, M.J., Low threshold calcium electrogenesis in neocortical neurons, Neurosci Lett., 81 (1987) 117-122.
18. [18] Friedman, A. and Gutnick, M.J., Intracellular calcium and control of burst generation in neurons of guinea-pig neocortex in vitro, Eur. J. Neurosci., 1 (1989) 374-381.
19. [19] Guatteo, E., Bacci, A., Franceschetti, S., Avanzini, G. and Wanke, E., Neurons dissociated from neocortex fire with 'burst' and 'regular' trains of spikes, Neurosci. Lett., 175 (1994) 117-120.
20. [20] Guatteo, E., Bacci, A., Franceschetti, S., Avanzini, G. and Wanke, E., Burst firing in single dissociated pyramidal cortical neurons is TTX-sensitive, Pflugers Arch., in press.
21. [21] Hamill, P.O., Huguenard, J.R. and Prince, D.A., Patch-clamp studies in identified neurons of the rat cerebral cortex, Cereb. Cortex, 1 (1991) 48-56.
22. - conductance in rat neocortical neurons: appearance of a slowly inactivating component, J. Neurophysiol., 59 (1988) 778-795.
23. [23] Josephson, I.R. and Sperelakis, N., Tetrodotoxin differentially blocks peak and steady-state sodium channel currents in early embryonic chick ventricular myocytes, Pflugers Arch., 414 (1989) 334-355.
24. [24] Kay, A.R., Miles, R. and Wong, K.S., Intracellular fluoride alters the kinetic properties of calcium currents facilitating the investigation of synaptic events in hippocampal neurons, J. Neurosci., 6 (1986) 2915-2920.
25. [25] Kay, A.R. and Wong, K.S., Isolation of neurons suitable for patch clamping from adult mammalian central nervous systems, J. Neurosci. Methods, 16 (1986) 227-238.
26. [26] Kim, H.G. and Connors, B.W., Apical dendrites of the neocortex: correlation between calcium-dependent spiking and pyramidal cell morphology, J. Neurosci., 13 (1993) 5301-5311.
27. [27] Kostyuk, P.G. and Krishtal, O.A., Separation of sodium and calcium currents in the somatic membrane of molluse neurons, J. Physiol. (Lond.), 270 (1977) 545-568.
28. [28] Llinas, R. and Yarom, Y., Properties and distribution of ionic conductances generating electroresponsiveness of mammalian inferior olivary neurons in vitro, J. Physiol. (Lond.), 315 (1981) 569-584.
29. [29] Mason, A. and Larkman, A., Correlations between morphology and electrophysiology of pyramidal neurons in slices of rat visual cortex. II. Electrophysiology, J. Neurosci., 10 (1990) 1415-1428.
30. [30] Mattia, D., Hwa, G.G.C. and Avoli, M., Membrane properties of rat subicular neurons in vitro, J. Neurophysiol., 70 (1993) 1244-1248.
31. [31] Moorman, J.R., Kirsch, G.E., VanDongen, A.M., Joho, R.H. and Brown, A.M., Fast and slow gating of sodium channels encoded by a single mRNA, Neuron, 4 (1990) 243-252.
32. 2+ channels in dendrites, J. Neurosci., 13 (1993) 4609-4621.
33. [33] Saint, D.A., Yue-kun, J. and Gage, P.W., A persistent sodium current in rat ventricular myocytes, J. Physiol. (Lond.), 453 (1992) 219-231.
34. [34] Sayer, R.J., Schwindt, P.C. and Crill, W.E., High-and low-threshold calcium currents in neurons acutely dissociated from rat sensorimotor cortex, Neurosci. Lett., 120 (1990) 175-178.
35. [35] Schwindt, P.C. and Crill, W.E., Amplification of synaptic current by persistent sodium conductance in apical dendrite of neocortical neurons, J. Neurophysiol., 74 (1995) 2220-2224.
36. [36] Schwindt, P.C., Spain, W.J. and Crill, W.E., Influence of anomalous rectifier activation on afterhyperpolarizations of neurons from cat sensorimotor cortex in vitro, J. Neurophysiol., 59 (1988) 468-481.
37. [37] Silva, R.L., Amitai, Y. and Connors, B.W., Intrinsic oscillations of neocortex generated by layer 5 pyramidal neurons, Science, 251 (1991) 432-435.
38. [38] Spain, W.J., Schwindt, P.C. and Crill, W.E., Two transient potassium currents in layer V pyramidal neurons from cat sensorimotor cortex, J. Physiol. (Lond.), 434 (1991) 591-607.
39. [39] Stafstrom, C.E., Schwindt, P.C., Chubb, M.C. and Crill, W.E., Properties of persistent sodium conductance and calcium conductance of layer 5 neurons from cat sensorimotor cortex in vitro, J. Neurophysiol., 53 (1985) 153-170.
40. [40] Takahashi, K., Wakamori, M. and Akaike, N., Hippocampal CA1 pyramidal cells of rats have four voltage-dependent calcium conductances, Neurosci. Lett., 104 (1989) 229-234.
41. + currents that fail to inactivate, Trends Neurosci., 16 (1993) 455-460.
42. [42] Tseng, G.F. and Prince, D.A., Heterogeneity of rat corticospinal neurons, J. Camp. Neurol., 335 (1993) 92-108.
43. 2+ spikes in rat sensory neurons: a perforated-patch study, Eur. J. Neurosci., 4 (1992) 723-732.
44. 2+ current in rat sympathetic neurons. Proc. Natl. Acad. Sci. USA, 84 (1987) 4313-4317.