Enhancement of quantal transmitter release and mediatophore expression by cyclic AMP in fibroblasts loaded with acetylcholine

Neuroscience

Volumn 75, Issue 2, 1996, Pages 353-360

  Falk Vairant, J ^a   Israel M ^b   Bruner, J ^b   Stinnakre, J ^b   Meunier, F M ^b   Gaultier, P ^b   Meunier, F ^b   Lesbats, B ^b   Synguelakis, M ^c   Correges P ^a   Dunant, Y ^a  

^a UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

^b LABORATOIRE DE NEUROBIOLOGIE CELLULAIRE ET MOLÉCULAIRE   (France)

^c CNRS   (France)

Author keywords

acetylcholine; cyclic AMP; fibroblasts; mediatophore; quantal transmitter release

Indexed keywords

ACETYLCHOLINE; BUCLADESINE; CYCLIC AMP;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL LINE; CELL STRUCTURE; CONTROLLED STUDY; ELECTROPHYSIOLOGY; FIBROBLAST; MOUSE; MUSCLE CELL; NEUROTRANSMITTER RELEASE; NONHUMAN; PRIORITY JOURNAL; XENOPUS;

EID: 0030601732     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/0306-4522(96)00260-6     Document Type: Article

References (22)

1. Bevan S., Grampp W., Miledi R.B. Properties of spontaneous potentials at denervated motor endplates of the frog. Proc. R. Soc. Lond. B. 194:1976;195-210.
2. Birman S., Meunier F.M., Lesbats B., LeCaer J.P., Rossier J., Israël M. A 15 kD proteolipid found in mediatophore preparations from Torpedo presents high sequence homology with the bovine chromatin granule protonophore. Fedn Eur. biochem. Socs Lett. 261:1990;303-306.
3. Brochier G., Israël M., Lesbats B. Immunolabelling of the presynaptic membrane of Torpedo electric organ nerve terminals with an antiserum towards the acetylcholine releasing protein mediatophore. Biol. Cell. 78:1993;145-154.
4. Dan Y., Poo M.M. Calcium-dependent postsynaptic exocytosis: a possible mechanism for activity-dependent synaptic modulation. J. Neurobiol. 25:1994;336-341.
5. Dunant Y., Israël M. Ultrastrusture and biophysics of acetylcholine release: central role of the mediatophore. J. Physiol., Paris. 87:1993;179-192.
6. Evers J., Laser M., Sun Y., Xie Z., Poo M.M. Studies of nerve-muscle interactions in Xenopus cell culture: analysis of early synaptic currents. J. Neurosci. 9:1989;1523-1539.
7. Falk-Vairant J., Corrèges P., Eder-Colli L., Salem N., Meunier F., Lesbats B., Loctin F., Synguelakis M., Israël M. and Dunant Y. (1996) Evoked acetylcholine release expressed by transfection of mediatophore cDNA. J. Neurochem. 66, (in press).
8. Falk-Vairant J., Corrèges P., Eder-Colli L., Salem N., Roulet E., Bloc A., Meunier F., Lesbats B., Loctin F., Synguelakis M., Israël M. and Dunant Y. (1996) Quantal acetylcholine release induced by mediatophore transfection. Proc. natn. Acad. Sci. U.S.A. (in press).
9. Falk-Vairant J., Dunant Y., Israël M. Quantal acetylcholine release in reconstituted systems. J. Neurochem. 63:1994;S90.
10. Fisher L.J., Schinstine M., Salvaterra P., Dekker A.J., Thai L., Gage F.H. In vivo production and release of acetylcholine from primary fibroblasts genetically modified to express choline acetyltransferase. J. Neurochem. 61:1993;1323-1332.
11. Girod R., Popov S., Alder J., Zheng J.Q., Lohof A., Poo M.M. Spontaneous quantal transmitter secretion from myocytes and fibroblasts: comparison with neuronal secretion. J. Neurosci. 15:1995;2826-2838.
12. Hamill O.P., Marty A., Neher A., Sakmann B., Sigworth F.J. Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pfluegers Arch. 391:1981;85-100.
13. Hamprecht B. Structural, electrophysiological, biochemical and pharmacological properties of neuroblastoma glioma cell hybrids in cell culture. Int. Rev. Cytol. 49:1977;99-170.
14. Israël M., Lesbats B. Continuous determination by a chemiluminescent method of acetylcholine release and compartmentation in Torpedo electric organ synaptosomes. J. Neurochem. 37:1981;1475-1483.
15. Israël M., Lesbats B. Application to mammalian tissues of the chemiluminescent method for detecting acetylcholine. J. Neurochem. 39:1982;248-250.
16. Israël M., Lesbats B., Synguelakis M., Joliot A. Acetylcholine accumulation and release by hybrid NG108-15, glioma and neuroblastoma cells - role of a 16 kDa membrane protein in release. Neurochem. Int. 25:1994;103-109.
17. Israël M., Morel N., Lesbats B., Birman S., Manaranche R. Purification of a presynaptic membrane protein that mediates a calcium-dependent translocation of acetylcholine. Proc. natn. Acad. Sci. U.S.A. 83:1986;9226-9230.
18. Kidokoro Y., Rohrbough J. Acetylcholine receptor channels in Xenopus myocyte culture; brief openings, brief closures and slow desensitization. J. Physiol., Lond. 425:1990;227-244.
19. Kimura Y., Oda Y., Deguchi T., Higashida H. Enhanced acetylcholine secretion in neuroblastoma × glioma hybrid NG108-15 cells transfected with rat acetyltransferase cDNA. Fedn Eur. biochem. Socs Lett. 314:1992;409-412.
20. Morimoto T., Popov S., Buckley K.M., Poo M.M. Calcium-dependent transmitter secretion from fibroblasts: modulation by synaptotagmin I. Neuron. 15:1995;689-696.
21. Nelson N. Organellar proton-ATPases. Curr. Opin. Cell Biol. 4:1992;654-660.
22. Parsons S.M., Prior C., Marshall I.G. Acetylcholine transport, storage, and release. Int. Rev. Neurobiol. 35:1993;279-390.