The Drosophila secreted protein Argos regulates signal transduction in the Ras/MAPK pathway

Developmental Biology

Volumn 178, Issue 1, 1996, Pages 13-22

  Sawamoto, Kazunobu ^a,b   Okabe, Masataka ^a,c   Tanimura, Teiichi ^d   Mikoshiba, Katsuhiko ^a,b,e,f   Nishida, Yasuyoshi ^g   Okano, Hideyuki ^a  

^a UNIVERSITY OF TSUKUBA   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d KYUSHU UNIVERSITY   (Japan)

^e INST OF PHYS AND CHEMICAL RESEARCH   (Japan)

^f Calciosignal Net Project   (Japan)

^g NAGOYA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; EPIDERMAL GROWTH FACTOR;

ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; DROSOPHILA; EYE DEVELOPMENT; FORELIMB; GENE FUNCTION; GENE MUTATION; GENE REPRESSION; NERVE CELL; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; SIGNAL TRANSDUCTION;

EID: 0030601319     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1006/dbio.1996.0194     Document Type: Article

References (55)

1. Ambrosio, L., Mahowald, A. P., and Perrimon, N. (1989). Requirement of the Drosophila raf homologue for torso function. Nature 342, 288-291.
2. Baker, N. E., and Rubin, G. M. (1989). Effect on eye development of dominant mutations in Drosophila homologue of the EGF receptor. Nature 340, 150-153.
3. Baker, N. E., and Rubin, G. M. (1992). Ellipse mutations in the Drosophila homologue of the EGF receptor affect pattern formation, cell division, and cell death in eye imaginal discs. Dev. Biol. 150, 381-396.
4. Banerjee, U., Renfraz, P. J., Pollock, J. A., and Benzer, S. (1987). Molecular characterization and expression of sevenless, a gene involved in neuronal pattern formation in the Drosophila eye. Cell 49, 281-291.
5. Basler, K., and Hafen, E. (1988). Control of photoreceptor cell fate by the sevenless protein requires a functional tyrosine kinase domain. Cell 54, 299-311.
6. Basler, K., Christen, B., and Hafen, E. (1991). Ligand-independent activation of the sevenless receptor tyrosine kinase changes the fate of cells in the developing Drosophila eye. Cell 64, 1069-1082.
7. Begemann, G., Michon, A.-M., Voorn, L., Wepf, R., and Mlodzik, M. (1995). The Drosophila orphan nuclear receptor Seven-up requires the Ras pathway for its function in photoreceptor determination. Development 121, 225-235.
8. Biggs, W. H., and Zipursky, S. L. (1992). Primary structure, expression, and signal-dependent tyrosine phosphorylation of a Drosophila homolog of extracellular signal-regulated kinase. Proc. Natl. Acad. Sci. USA 89, 6295-6299.
9. Biggs, W. H., Zavitz, K. H., Dickson, B., Straten, A., Brunner, D., Hafen, E., and Zipursky, S. L. (1994). The Drosophila rolled locus encodes a MAP kinase required in the sevenless signal transduction pathway. EMBO J. 13, 1628-1635.
10. Bowtell, D. D. L., Simon, M. A., and Rubin, G. M. (1988). Nucleotide sequence and structure of the sevenless gene of Drosophila melanogaster. Genes Dev. 2, 620-634.
11. Brunner, D., Oeller, N., Szabad, J., Biggs, W. H., III, Zipursky, S. L., and Hafen, E. (1994a) A gain-of-function mutation in Drosophila MAP kinase activates multiple receptor tyrosine kinase signaling pathways Cell 76, 875-888.
12. Brunner, A., Twardzik, T., and Schneuwly, S. (1994b). The Drosophila giant lens gene plays a dual role in eye and optic lobe development: Inhibition of differentiation of ommatidial cells and interference in photoreceptor axon guidance. Mech. Dev. 48, 175-185.
13. Cochet, C., Gill, G. N., Meisenhelder, J., Cooper, J. A., and Hunter, T. (1984). C-kinase phosphorylates the epidermal growth factor receptor and reduces its epidermal growth factor-stimulated tyrosine protein kinase activity. J. Biol. Chem. 259, 2553-2558.
14. Cullen, P. J., Hsuan, J. J., Truong, O., Letcher, A. J., Jackson, T. R., Dawson, A. P., and Irvine, R. F. (1995). Identification of a specific Ins(1,3,4,5)P4-binding protein as a member of the GAP family. Nature 376, 527-530.
15. Diaz-Benjumea, F., and Galcia-Bellido, A. (1990). Behavior of cell mutant for an EGF receptor homologue of Drosophila in genetic mosaics. Proc. R. Soc. London Biol. Sci. 242, 36-44.
16. Diaz-Benjumea, F., and Hafen, E. (1994). The sevenless signaling cassette mediates Drosophila EGF receptor function during epidermal development. Development 120, 569-578.
17. Dickson, B., Sprenger, F., Morrison, D., and Hafen, E. (1992). Raf functions downstream of Ras1 in the Sevenless signal transduction pathway. Nature 360, 600-603.
18. Dickson, B., and Hafen, E. (1993). Genetic dissection of eye development in Drosophila. In "The Development of Drosophila melanogaster. (M. Bate, and A. Martinez Ariaz, Eds.), pp. 1327-1362. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
19. Dickson, B., and Hafen, E. (1994). Genetics of signal transduction in invertebrates. Curr. Opin. Genet. Dev. 4, 64-70.
20. Doyle, H. J., and Bishop, J. M. (1993). Torso, a receptor tyrosine kinase required for embryonic pattern formation, shares substrates with the sevenless and EGF-R pathways in Drosophila. Genes Dev. 7, 633-646.
21. Fehon, R. G., Kooh, P. J., Rebay, I., Regan, C. L., Xu, T., Muskavitch, M. A. T., and Artavanis-Tsakonas, S. (1990). Molecular interactions between the protein products of the neurogenic loci Notch and Delta, two EGF-homologous genes in Drosophila. Cell 61, 523-534.
22. Fortini, M. E., Simon, M. A., and Rubin, G. M. (1992). Signaling by the sevenless protein tyrosine kinase is mimicked by Ras1 activation. Nature 355, 559-561.
23. Freeman, M. (1994a). The spitz gene is required for photoreceptor determination in the Drosophila eye where it interacts with the EGF receptor. Mech. Dev. 48, 25-33.
24. Freeman, M. (1994b). Misexpression of the Drosophila argos gene, a secreted regulator of cell determination. Development 120, 2297-2340.
25. Freeman, M., Klämbt, C., Goodman, C. S., and Rubin, G. M. (1992). The argos gene encodes a diffusible factor that regulates cell fate decisions in the Drosophila eye. Cell 69, 963-975.
26. Gaul, U., Mardon, G., and Rubin, G. M. (1992). A putative Ras GTPase activating protein acts as a negative regulator of signaling by the sevenless receptor tyrosine kinase. Cell 68, 1007-1019.
27. Hafen, E., Basler, K., Edstroem, J. E., and Rubin, G. M. (1987). sevenless, a cell-specific homeotic gene of Drosophila, encodes a putative transmembrane receptor with a tyrosine kinase domain. Science 236, 55-63.
28. Heberlein, U., Hariharan I. K., and Rubin, G. M. (1993). Star is required for neuronal differentiation in the Drosophila retina and displays dosage-sensitive interactions with ras1. Dev. Biol. 160, 51-63.
29. Heitzler, P., and Simpson, P. (1991). The choice of cell fate in the epidermis of Drosophila. Cell 64, 1083-1092.
30. Hou, X. S., Chou, T.-B., Melnick, M. B., and Perrimon, N. (1995). The Torso receptor tyrosine kinase can activate Raf in a Ras-independent pathway. Cell 81, 63-71.
31. Hsu, J., and Perrimon, N. (1994). A temperature-sensitive MEK mutation demonstrates the conservation of the signaling pathways activated by receptor tyrosine kinases. Genes Dev. 8, 2176-2187.
32. Klingler, M., Erdélyi, M., Szabad, J., and Nüsslein-Volhard, C. (1988). Function of torso in determining the terminal anlagen of the Drosophila embryo. Nature 335, 275-277.
33. Kolodkin, A. L., Pickup, A. M., Lin, D. M., Goodman, C. S., and Banerjee, U. (1994). Characterizing of Star and its interactions with sevenless and EGF receptor during photoreceptor cell development in Drosophila. Development 120, 1731-1745.
34. Kretzschmar, D., Brunner, A., Wiersdorff, V., Pflugfelder, G. O., Heisenberg, M., and Schneuwly, S. (1992). ginat lens, a gene involved in cell determination and axonal guidance in the visual system of Drosophila melanogaster. EMBO J. 11, 2531-2539.
35. Lu, X., Melnick, M. B., Hsu, J.-C., and Perrimon, N. (1994). Genetic and molecular analyses of mutations involved in Drosophila raf signal transduction. EMBO J. 13, 2592-2599.
36. Nishida, Y., Hata, M., Ayaki, T., Ryo, H., Yamagata, M., Shimizu, K., and Nishizuka, Y. (1988). Proliferation of both somatic and germ cells is affected in the Drosophila mutants of raf proto-oncogene. EMBO J. 7, 775-781.
37. Okabe, M., Sawamoto, K., and Okano, H. (1996). The function of Drosophila argos gene product in the development of embryonic chordotonal organs. Dev. Biol. 175, 37-49.
38. Okano, H., Hayashi, S., Tanimura, T., Sawamoto, K., Yoshikawa, S., Watanabe, J., Iwasaki, M., Hirose, S., Mikoshiba, K., and Montell, C. (1992). Regulation of Drosophila neural development by a putative secreted protein. Differentiation 52, 1-11.
39. Olivier, J. P., Raabe, T., Henkemeyer, M., Dickson, B., Mbamalu, G., Margolis, B., Schlessinger, J., Hafen, E., and Pawson, T. (1993). A Drosophila SH2-SH3 adaptor protein implicated in coupling the Sevenless tyrosine kinase to an activator of Ras guanine nucleotide exchange, Sos. Cell 73, 179-191.
40. Rebay, I., Fleming, R. J., Fehon, R. G., Cherbas, P., and Artavanis-Tsakonas, S. (1991). Specific EGF repeats of Notch mediate interactions with Delta and Serrate: Implications for Notch as a multi-functional receptor. Cell 67, 687-699.
41. Rogge, R. D., Kariovich, C. A., and Banerjee, U. (1991). Genetic dissection of a neurodevelopmental pathway: Son of sevenless functions downstream of the sevenless and EGF receptor tyrosine kinases. Cell 64, 39-48.
42. Sawamoto, K., Okano, H., Kobayakawa, Y., Hayashi, S., Mikoshiba, K., and Tanimura, T. (1994). The function of argos in regulating cell fate decisions during Drosophila eye and wing vein development. Dev. Biol. 164, 267-276.
43. Sawamoto, K., Okabe, M., Tanimura, T., Hayashi, S., Mikoshiba, K., and Okano, H. (1996). argos is required for projection of photoreceptor axons during optic lobe development in Drosophila. Dev. Dyn. 205, 162-171.
44. Schüpbach, T. (1987). Germ line and soma cooperate during oogenesis to establish the dorsoventral pattern of the egg shell and embryo in Drosophila melanogaster. Cell 49, 699-707.
45. Schweitzer, R., Howes, R., Smith, R., Shilo, B.-Z., and Freeman, M. (1995a). Inhibition fo Drosophila EGF receptor activation by the secreted protein Argos. Nature 376, 699-702.
46. Schweitzer, R., Shaharabany, M., Seger, R., and Shilo, B.-Z. (1995b). Secreted spitz triggers the DER signaling pathway and is a limiting component in embryonic ventral ectoderm determination. Genes Dev. 9, 1518-1529.
47. Simon, M. A., Bowtell, D. D., Dodson, G. S., Laverty, T. R., and Rubin, G. M. (1991). Ras1 and a putative guanine nucleotide exchange factor perform crucial steps in signaling by the sevenless protein tyrosine kinase. Cell 67, 701-716.
48. Simon, M. A., Dodson, G. S., and Rubin, G. M. (1993). An SH3-SH2-SH3 protein is required for p21Ras1 activation and binds to sevenless and Sos proteins in vitro. Cell 73, 169-177.
49. Sprenger, F., Stevens, L. M., and Nüsslein-Volhard, C. (1989). The Drosophila gene torso encodes a putative receptor tyrosine kinase. Nature 338, 478-483.
50. Sturtevant, M. A., Roark, M., and Bier, E. (1993) The Drosophila rhomboid gene mediates localized formation of wing veins and interacts genetically with components of the EGF-R signaling pathway. Genes Dev. 7, 961-973.
51. Tio, M., Ma, C., and Moses, K. (1994). spitz, a Drosophila homolog of transforming growth factor-α, is required in the founding photoreceptor cells of the compound eye facets. Mech. Dev. 48, 13-23.
52. Tomlinson, A., and Ready, D. F. (1986). Sevenless, a cell-specific homeotic mutation of the Drosophila eye. Science 231, 400-402.
53. Tsuda, L., Inoue, Y. H., Yoo, M., Mizuno, M., Hata, M., Lim, Y., Adachi-Yamada, T., Ryo, H., Masamune, Y., and Nishida, Y. (1993). A protein kinase similar to MAP kinase activator acts downstream of the raf kinase in Drosophila. Cell 72, 407-414.
54. Wemmer, T., and Klàmbt, C. (1995). A genetic analysis of the Drosophila closely linked interacting genes bulge, argos and soba. Genetics 140, 629-641.
55. Xu, T., and Rubin, G. M. (1993). Analysis of genetic mosaics in developing and adult Drosophila tissues. Development 117, 1223-1237.