Induction or suppression of SV40 amplification by genotoxic carcinogens, non-genotoxic carcinogens or tumor promoters

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 356, Issue 2, 1996, Pages 217-224

  Fahrig, Rudolf ^a   Steinkamp Zucht, Angela ^a  

^a FRAUNHOFER INSTITUTE FOR TOXICOLOGY AND EXPERIMENTAL MEDICINE   (Germany)

Author keywords

(E) 5 (2 Bromovinyl) 2' deoxyuridine; 12 O Tetradecanoylphorbol 13 acetate; 4 Nitroquinoline 1 oxide; Acetamide; Acetone; Chrysarobin; Coumarin; Gene amplification; Mezerin; N,n Dimethylformamide; Testosterone; Thioacetamide; Triethylenemelamine

Indexed keywords

4 NITROQUINOLINE 1 OXIDE; 5 (2 BROMOVINYL) 2' DEOXYURIDINE; ACETONE; CARCINOGEN; CHRYSAROBIN; COUMARIN; METHOTREXATE; MEZEREIN; N,N DIMETHYLFORMAMIDE; PHORBOL 13 ACETATE 12 MYRISTATE; TESTOSTERONE; THIOACETAMIDE; TIOGUANINE; TRETAMINE; TUMOR PROMOTER;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; GENE AMPLIFICATION; GENOTOXICITY; HAMSTER; METABOLIC ACTIVATION; NONHUMAN; PRIORITY JOURNAL; SIMIAN VIRUS 40; VIRUS REPLICATION;

EID: 0030599158     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/0027-5107(96)00061-9     Document Type: Article

References (38)

1. [1] Weisburger, J.H. and G.M, Williams (1981) Carcinogen testing: current problems and new approaches, Science, 214, 401-407.
2. [2] Lutz, W.K. and P. Maier (1988) Genotoxic and epigenetic chemical carcinogenesis: one process, different mechanism, TIPS, 9, 322-326.
3. [3] Perera, F.P. (1991) Perspectives on the risk assessment for nongenotoxic carcinogens and tumor promoters, Environ. Health Perspect., 94, 231-235.
4. [4] Ashby, J. and F.H. Purchase (1992) Nongenotoxic carcinogens: An extension of the perspective provided by Perera, Environ. Health Perspect., 98, 223-226.
5. [5] Ames, B. and L.S. Gold (1990) Carcinogenesis debate, Science, 250, 1498-1499.
6. [6] Ames, B., M.K. Shigenaraand and L.S. Gold (1993) DNA lesions, inducible DNA repair, and cell division: Three factors in mutagenesis and carcinogenesis, Env. Health Perspect., 101, 35-44.
7. [7] Fahrig, R. (1979) Evidence that induction and suppression of mutations and recombinations by chemical mutagens in S. cerevisiae during mitosis are jointly correlated, Mol. Gen. Genet., 169, 125-139.
8. [8] Fahrig, R. (1984) Genetic mode of action of cocarcinogens and tumor promoters in yeast and mice. Mol. Gen. Genet., 194, 7-14.
9. [9] Fahrig, R. (1987) Effects of bile acids an the mutagenicity and recombinogenicity of triethylene melamine in yeast strain MP1 and D61.M, Arch. Toxicol., 60, 192-197.
10. [10] Fahrig, R. (1987) Enhancement of carcinogen-induced mutations or recombinations by 12-O-tetradecanoylphorbol 13-acetate in the mammalian spot test, J. Cancer Res. Clin. Oncol., 113, 61-66.
11. [11] Fahrig, R. (1992) Co-recombinagenic effects, Mutation Res., 284, 185-193.
12. [12] Fahrig, R. (1993) Genetic effects of dioxins in the spot test with mice, Environ. Health Perspect., 101, 257-261.
13. [13] Fahrig, R. (1996) Anti-mutagenic agents are also co-recombinogenic and can be converted into co-mutagens, Mutation Res., 350, 59-67.
14. [14] De la Rosa, M.E., J. Magnusson, C. Ramel and R. Nilsson (1994) Modulation influence of inorganic arsenic on the recombinogenic and mutagenic action of ionizing radiation and alkylating agents in Drosophila melanogaster, Mutation Res., 318, 65-71.
15. [15] Hill, A.B. and R.T. Schimke (1985) Increased gene amplification in L 51784 mouse lymphoma cells with hydroxyurea-induced chromosomal aberrations, Cancer Res., 45, 5050-5057.
16. [16] Barsoum, J. and A. Vershavsky (1983) Mitogenic hormones and tumor promotors greatly increase the incidence of colony-forming cells bearing amplified dihydrofolate reductase genes, Proc. Natl. Acad. Sci. USA, 80, 5330-5334.
17. [17] Butterworth, B.E. and T.J. Slaga (1987) Nongenotoxic mechanisms in carcinogenesis, Banbury report No, 25, Cold Spring Harbor Laboratory
18. [18] Klein, P., B.L. Pool-Zobel, A.Ö. Yalkinglu and J.R. Schlehofer (1990) Modellsysteme zur Erfassung selektiver DNA-Amplifikation: DNA-Amplifikation in SV40 transformierten CO631-Zellen und AAV-DNA Amplification in primären Zellen, GUM, 2, 8-13.
19. [19] Lavi, S. (1981) Carcinogen-mediated amplification of viral DNA sequences in simian virus 40 transformed Chinese hamster ovary cells, Proc. Natl. Acad. Sci. USA, 78, 6144-6148.
20. [20] Lavi, S. (1982) Carcinogen-mediated activation of SV40 replicons: A model for initiation of carcinogenesis, in: RT Schimke (Ed.), Gene Amplification, Cold Spring Harbor Laboratory, New York.
21. [21] Lavi, S. and S. Etkin (1981) Carcinogen-mediated induction of SV40 DNA synthesis in SV40 transformed Chinese hamster embryo cells, Carcinogenesis, 2, 417-423.
22. [22] Pool, B.L.A., Ö. Yalkinoglu, P. Klein and J.R. Schlehofer (1989) DNA amplification in genetic toxicology, Mutation Res., 213, 61-72.
23. [23] Varshavsky, A. (1981) Phorbol ester dramatically increases incidence of methotrexate-resistent mouse cells: possible mechanisms and relevance to tumor promotion, Cell, 25, 561-572.
24. [24] Yalkinoglu, Ö. and H. zur Hausen (1987) Carcinogen-induced DNA amplification of helper-virus-dependent parvoviruses, Accompl. Oncol., 2, 153-160.
25. [25] Rossman, T.G. and D. Wolosin (1992) Differential susceptibility to carcinogen-induced amplification of SV40 and dhfr sequences in SV40-transformed human keratinocytes, Mol. Carcinogen., 6, 203-213.
26. [26] Marquardt, H., J. Westendorf, E. De Clercq and H. Marquardt (1985) Potent anti-viral 5-(2-bromovinyl) uracil nucleosides are inactive at inducing mutations in Salmonella typhimurium and V79 Chinese hamster cells and unscheduled DNA synthesis in orimary rat hepatocytes, Carcinogenesis, 6, 1207-1209.
27. [27] Oshiro, Y.C., E. Piper, P.S. Balwierz and M.L. Garriot (1992) Genotoxic properties of (E)-5-(2-bromovinyl)-2́-deoxyuridine (BVDU), Fund. Applied Toxicol., 18, 491-498.
28. [28] Meinkoth, J. and G. Wahl (1984) Hybridization of nucleic acids immobilized on solid supports, Anal. Biochem., 138, 267-284.
29. [29] Kleinberger, T., S. Etkin and S. Lavi (1986) Carcinogenmediated methotrexate resistance and dihydrofolate reductase amplification in Chinese hamster cells, Mol. Cell Biol., 6, 1958-1964.
30. [30] Schimke, R.T., S.W. Sherwood, A.B. Hill and R.N. Johnston (1986) Overreplication and recombination of DNA in higher eukaryotes: potential consequences and biological implications, Proc. Natl. Acad. Sci. USA, 83, 2157-2161.
31. [31] Volkert, F.C. and J.R. Broach (1986) Site-specific recombination promotes plasmid amplification in yeast, Cell, 46, 541-550.
32. [32] Lang, R. and U. Redmann (1979) Non-mutagenicity of some sex hormones in the Ames Salmonella/microsome mutagenicity test, Mutation Res., 67, 361-365.
33. [33] Sekiya, S., Y. Kikuchi, T. Katoh, W. Kobayashi, B. Takeda and H. Takamizawa (1979) Effect of ovariectomy, adrenalectomy, and hypophysectomy on carcinogenesis of the endometrium by 7,12-dimethylbenz[a]anthacene in rats, Gynecol. Oncol., 7, 281-7.
34. [34] Wessely, Z. and J.V. Klavins (1972) Uterine and mammary neoplasia and other changes (amyloidosis) in C3H mice, related to ovariectomy, estrogen and methylcholanthrene, Oncology, 26, 33-52.
35. [35] Sheehan, D.M., C.B. Frederick, W.S. Branham and J.E Heath (1982) Evidence for estradiol promotion of neoplastic lesions in the rat vagina after initiantion with N-methyl-N-nitrosourea, Carcinogenesis, 3, 957-959.
36. [36] Malkinson, A.M. and L.G. Thaete (1986) Effects of strain and age on prophylaxis and co-carcinogenesis of urethan-induced mouse lung adenomas by butylated hydroxytoluene, Cancer Res., 46, 1694-1697.
37. [37] Wahl, G.M. (1989) The importance of circular DNA in mammalian gene amplification, Cancer Res., 49, 1333-1340.
38. [38] Stark, G.R., M. Debatisse, E. Giulotto and G.M. Wahl (1989) Recent progress in understanding mechanisms of mammalian DNA amplification. Cell, 57, 901-908.