Blockade of isoproterenol-induced synaptic potentiation by tetra-9-aminoacridine in the rat amygdala

Neuroscience Letters

Volumn 214, Issue 2-3, 1996, Pages 87-90

  Wang, Su Jane ^a   Huang, Chiung Chun ^a   Hsu, Kuei Sen ^a   Tsai, Jing Jane ^a   Huang, Chao Ching ^b   Gean, Po Wu ^a  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^b NATIONAL CHENG KUNG UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Amygdala; Forskolin; Isoproterenol; Long term potentiation; Tetrahydro 9 aminoacridine

Indexed keywords

2 AMINO 5 PHOSPHONOVALERIC ACID; BETA ADRENERGIC RECEPTOR; CALCIUM CHANNEL; FORSKOLIN; ISOPRENALINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; TACRINE;

AMYGDALOID NUCLEUS; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; LONG TERM POTENTIATION; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0030599024     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/0304-3940(96)12892-5     Document Type: Article

References (18)

1. [1] Costa, A.C.S. and Albuquerque, E.X., Dynamics of the actions of tetrahydro-9-aminoacridine and 9-aminoacridine on glutamatergic currents: concentration-jump studies in cultured rat hippocampal neurons, J. Pharmacol. Exp. Ther., 268 (1994) 503-514.
2. [2] Drukarch, B., Kits, K.S., Van Der Meer, E.G., Lodder, J.C. and Stoof, J.C., 9-Amino-1,2,3,4-tetrahydroacridine (THA), an alleged drug for the treatment of Alzheimer's disease, inhibits acetylcholinesterase activity and slow outward K current, Eur. J. Pharmacol., 141 (1987) 153-157.
3. [3] Dutar, P., Bassant, M.H. and Lamour, Y., Effects of tetrahydro-9-aminoacridine on cortical and hippocampal neurons in the rat: an in vivo and in vitro study, Brain Res., 527 (1990) 32-40.
4. [4] Eagger, S.A., Levy, R. and Sahakian, B.J., Tacrine in Alzheimer's disease, Lancet, 337 (1991) 989-992.
5. [5] Freeman, S.E. and Dawson, R.M., Tacrine: a pharmacological review, Prog. Neurobiol., 36 (1991) 257-277.
6. [6] Gean, P.W., Huang, C.C., Lin, J.H. and Tsai, J.J., Sustained enhancement of NMDA receptor-mediated synaptic potential by isoproterenol in rat amygdalar slices, Brain Res., 594 (1992) 331-334.
7. [7] Halliwell, J.V. and Grover, E.A., 9-Amino-1,2,3,4-tetrahydroacridine (THA) blocks agonist-induced potassium conductance in rat hippocampal neurons, Eur. J. Pharmacol., 163 (1989) 369-372.
8. [8] Hershkowitz, N. and Rogawski, M.A., Tetrahydroaminoacridine block of N-methyl-D-aspartate activated cation channels in cultured hippocampal neurons, Mol. Pharmacol., 39 (1991) 592-598.
9. [9] Hodges, H., Ribeiro, A.M., Gray, J.A. and Marchbanks, R.M., Low dose tetrahydroaminoacridine (THA) improves cognitive function but does not affect brain acetylcholine in rats, Pharmacol., Biochem. Behav., 36 (1990) 291-298.
10. [10] Huang, C.C., Hsu, K.S. and Gean, P.W., Isoproterenol potentiates synaptic transmission primarily by enhancing presynaptic calcium influx via P-and/or Q-type calcium channels in the rat amygdala, J. Neurosci., 16 (1996) 1026-1033.
11. [11] Kelly, K.M., Gross, R.A. and Macdonald, T.L., Tetrahydroaminoacridine (THA) reduces voltage-dependent calcium currents in rat sensory neurons, Neurosci. Lett., 132 (1991) 247-250.
12. [12] LeDoux, J.E., Emotion and the amygdala. In J.P. Aggleton (Ed.), The Amygdala, Wiley-Liss, New York, 1992, pp. 339-351.
13. [13] McGaugh, J.L., Introini-Collison, I.B., Cahill, L., Kim, M. and Liang, K.C., Involvement of the amygdala in neuromodulatory influences on memory storage. In J.P. Aggleton (Ed.), The Amygdala, Wiley-Liss, New York, 1992, pp. 431-451.
14. [14] Rogawski, M.A., Tetrahydroaminoacridine blocks voltage-dependent ion channels in hippocampal neurons, Eur. J. Pharmacol., 142 (1987) 169-172.
15. [15] Stevens, D.R. and Cotman, C.W., Excitatory actions of tetrahydro-9-aminoacridine (THA) on hippocampal pyramidal neurons, Neurosci. Lett., 79 (1987) 301-305.
16. [16] Summers, W.K., Majovski, L.V., Marsh, G.M., Tachiki, K. and Kling, A., Oral tetrahydroaminoacridine in long-term treatment of senile dementia, Alzheimer's type, N. Engl. J. Med., 315 (1986) 1241-1245.
17. [17] Vivas, N.M., Marmol, F., Salles, J., Badia, A. and Dierssen, M., Action on noradrenergic transmission of an anticholinesterase: 9-amino-1,2,3,4-tetrahydroacridine, Neuropharmacology, 34 (1995) 367-375.
18. [18] Wang, S.J., Huang, C.C. and Gean, P.W., Investigation on the mechanism of tetrahydro-9-aminoacridine-induced presynaptic inhibition in the rat amygdala, Neuroscience, 70 (1996) 409-415.