D3 receptor expression within the basal ganglia is not affected by Parkinson's disease

Neuroscience Letters

Volumn 214, Issue 2-3, 1996, Pages 75-78

  Hurley, Michael J ^a   Stubbs, Carole M ^b   Jenner, Peter ^a   Marsden, C David ^c  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

^c NATIONAL HOSPITAL FOR NEUROLOGY AND NEUROSURGERY   (United Kingdom)

Author keywords

Basal ganglia; Dopamine D3 receptor; In situ hybridization; Parkinson's disease; Receptor autoradiography

Indexed keywords

2 DIPROPYLAMINO 7 HYDROXYTETRALIN; DOPAMINE 3 RECEPTOR; MESSENGER RNA; QUINOLINIC ACID;

ADULT; AGED; ARTICLE; AUTORADIOGRAPHY; CLINICAL ARTICLE; CONTROLLED STUDY; CORPUS STRIATUM; FEMALE; HUMAN; HUMAN TISSUE; LIMBIC CORTEX; MALE; PARKINSON DISEASE; PRIORITY JOURNAL;

EID: 0030598973     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/0304-3940(96)12884-6     Document Type: Article

References (18)

1. [1] Alexander, G.M., Schwartzman, R.J., Grothusen, J.R., Brainard, L. and Gordon, S.W., Changes in brain dopamine receptors in MPTP parkinsonian monkeys following L-dopa treatment, Brain Res., 625 (1993) 276-282.
2. [2] Bédard, P.J., Gomez-Mancilla, B., Blanchette, P., Gagnon, C., Falardeau, P. and Di Paolo, T., Role of selective D1 and D2 agonists in inducing dyskinesia in drug-naive MPTP monkeys, Adv. Neurol., 60 (1993) 113-118.
3. [3] Bouthenet, M.-L., Souil, E., Martres, M.-P., Sokoloff, P., Giros, B. and Schwartz, J.-C., Localization of dopamine D3 receptor mRNA in the rat brain using in situ hybridization histochemistry: comparison with dopamine D2 receptor mRNA, Brain Res., 564 (1991) 203-219.
4. [4] Gagnon, C., Bédard, P.J. and Dipaolo, T., Effect of chronic treatment of MPTP monkeys with dopamine D1 and/or D2 receptor agonists, Eur. J. Pharmacol., 178 (1990) 115-120.
5. [5] Gnanalingham, K.K., Smith, L.A., Hunter, A.J., Jenner, P. and Marsden, C.D., Alterations in striatal and extrastriatal D1 and D2 dopamine receptors in the MPTP-treated common marmoset: an autoradiographic study, Synapse, 14 (1993) 184-194.
6. [6] Graham, W.C., Sambrook, M.A. and Crossman, A.R., Differential effect of chronic dopaminergic treatment on dopamine D1 and D2 receptors in the monkey brain in MPTP-induced parkinsonism, Brain Res., 602 (1993) 290-303.
7. 3H]7-hydroxy-N,N-di-N-propyl-2-aminotetralin, Brain Res., 648 (1994) 222-228.
8. [8] Hornykiewicz, O., Parkinson's disease and its chemotherapy, Biochem. Pharmacol., 24 (1975) 1061-1065.
9. [9] Hurley, M.J., Jenner, P. and Marsden, C.D., Differential effect of dopamine depletion on the level of D2 and D3 receptor expression in rat basal ganglia, Br. J. Pharmacol., 115 (1995) 29P.
10. [10] Hurley, M.J., Jolkkonen, J., Stubbs, C.M., Jenner, P. and Marsden, C.D., Dopamine D3 receptors in the basal ganglia of the common marmoset and following MPTP and L-DOPA treatment, Brain Res., 709 (1996) 259-264.
11. 3H]mazindol autoradiography, J. Neurosci., 5 (1985) 1513-1521.
12. [12] Landwehrmeyer, B., Mengod, G. and Palacios, J.M., Dopamine D3 receptor mRNA and binding sites in human brain, Mol. Brain Res., 18 (1993) 187-192.
13. [13] Large, C.H. and Stubbs, C.M., The dopamine D3 receptor: Chinese hamsters of Chinese whispers, Trends Pharmacol. Sci., 15 (1994) 46-47.
14. 3H]-hydroxy-N,N-di-N-propyl-2-aminotetralin, Proc. Natl. Acad. Sci. USA, 89 (1992) 8155-8159.
15. [15] Lévesque, D., Martres, M.-P., Diaz, J., Griffon, N., Lammerds, C.L., Sokoloff, P. and Schwartz, J.-C., A paradoxical regulation of the dopamine D3 receptor expression suggests the involvement of an anterograde factor from dopamine neurons, Proc. Natl. Acad. Sci. USA, 92 (1995) 1719-1723.
16. [16] Nunez, D.J., Davenport, A.P., Emson, P.C. and Brown, M.J., A quantitative 'in-situ' hybridization method using computer-assisted image analysis, Biochem. J., 263 (1989) 121-127.
17. [17] Sautel, F., Griffon, N., Lévesque, D., Pilon, C., Schwartz, J.-C. and Sokoloff, P., A functional test identifies dopamine agonists selective for D3 and D2 receptors, NeuroReport, 6 (1995) 329-332.
18. [18] Sibley, D.R. and Monsma, F.J., Molecular biology of dopamine receptors, Trends Pharmacol. Sci., 13 (1992) 61-69.