Synthesis of CD-ring modified 1α,25-dihydroxy vitamin D analogues: E-ring analogues

Bioorganic and Medicinal Chemistry Letters

Volumn 6, Issue 14, 1996, Pages 1697-1702

  Sabbe, K ^a   D'Hallewyn, C ^a   De Clercq, P ^a   Vandewalle, M ^a   Bouillon, R ^b   Verstuyf, A ^b  

^a GHENT UNIVERSITY   (Belgium)

^b UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

CALCITRIOL; COLECALCIFEROL DERIVATIVE; VITAMIN D BINDING PROTEIN;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; CELL DIFFERENTIATION; CELL LINE; CHICKEN; CONTROLLED STUDY; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; REACTION ANALYSIS; STRUCTURE ACTIVITY RELATION; VITAMIN D DEFICIENCY;

ANIMALIA; GALLUS GALLUS;

EID: 0030598674     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/0960-894X(96)00300-9     Document Type: Article

References (19)

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19. 14. Eliminations using non-nucleophilic voluminous bases failed. Seemingly the steric congestion around C-20 allows only attack of F-.