Improvement of metabolic disorders and visceral rat obesity by the β3-adrenoceptor agonist (R*,R*)-(±)-methyl-4-[2-[2-hydroxy-2-(3-chlorophenyl)ethylamino]pro pyl]-phenoxyacetate hydrobromide (BRL35135A) in genetically obese rodents

Biochemical Pharmacology

Volumn 52, Issue 10, 1996, Pages 1529-1535

  Hashimoto, Koji ^a   Nagao, Yuji ^a   Ida, Keiichi ^a   Takeda, Mitsuhiro ^a   Murakami, Nobuya ^a   Kato, Katsuaki ^a   Mizota, Masahiro ^a  

^a MOCHIDA PHARMACEUTICAL CO   (Japan)

Author keywords

3 adrenoceptor agonist; body weight; genetically obese rodents; insulin resistance; lipolysis; visceral fat

Indexed keywords

4 [2 [[2 (3 CHLOROPHENYL) 2 HYDROXYETHYL]AMINO]PROPYL]PHENOXYACETIC ACID METHYL ESTER; ANTIDIABETIC AGENT; BETA 3 ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR STIMULATING AGENT;

ADIPOCYTE; ADIPOSE TISSUE; ANIMAL CELL; ANIMAL MODEL; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; DIGESTIVE SYSTEM; FEMALE; IN VITRO STUDY; LIPOLYSIS; MALE; NONHUMAN; OBESITY; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RAT;

ADIPOSE TISSUE; ADRENERGIC BETA-AGONISTS; ANIMALS; BLOOD GLUCOSE; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; INSULIN; INSULIN RESISTANCE; LIPOLYSIS; MALE; MICE; MICE, INBRED C57BL; MICE, OBESE; OBESITY; ORGAN SIZE; PHENETHYLAMINES; RATS; RATS, SPRAGUE-DAWLEY; RATS, WISTAR; RATS, ZUCKER; STEREOISOMERISM; TISSUE DISTRIBUTION; WEIGHT GAIN;

EID: 0030598412     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(96)00552-7     Document Type: Article

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