Guided evolution of enzymes with new substrate specificities

Journal of Molecular Biology

Volumn 264, Issue 1, 1996, Pages 97-110

  El Hawrani, A S ^a   Sessions, R B ^a   Moreton, K M ^a   Holbrook, J J ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

Gene libraries; Guided evolution; NAD dependent dehydrogenases; Substrate specificity; Surface loops

Indexed keywords

ATROLACTIC ACID; BUTYRIC ACID; FRUCTOSE 1,6 BISPHOSPHATE; LACTATE DEHYDROGENASE; MALATE DEHYDROGENASE; MALIC ACID; OXALOACETIC ACID; PHENYLPYRUVIC ACID; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE; VALINE;

AMINO ACID SEQUENCE; ARTICLE; CONTROLLED STUDY; DNA SEQUENCE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME SPECIFICITY; ENZYME STABILITY; EVOLUTION; GENE LIBRARY; GEOBACILLUS STEAROTHERMOPHILUS; HYDRODYNAMICS; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN FOLDING;

FELIS CATUS; GEOBACILLUS STEAROTHERMOPHILUS;

EID: 0030598368     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1996.0626     Document Type: Article

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